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57 (0,09s)

Project

The impact of pancreas transplantation on the course of diabetic autonomic neuropathy. (NB6394)

The aim of the current project is an evaluation of the impact of a successful pancreas transplantation on the course of diabetic autonomic neuropathy. Methods used for the follow-up include a battery of cardiovascular function tests, spectra...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2000 - 2002
  • 911 tis. Kč
  • 906 tis. Kč
  • MZ
Project

Radiofrequency ablation of pancreas (NS10239)

The purpose of this project is during two-phase ( first phase ex-vivo, second phase in-vivo) experimental study on porcine model, to work up methodics for safe radiofrequency ablation of pancreas, which could be used in human medicine subseq...

FJ - Chirurgie včetně transplantologie

  • 2009 - 2011
  • 4 796 tis. Kč
  • 4 796 tis. Kč
  • MZ
Project

The role of chronic inflammatory changes in pancreas in cancerogenesis (NR9295)

Tissue ischemia in chronic pancreatitis is one of the factors influencing oxidative stress; this stress is an important factor of changes leading towards carcinogenesis of the pancreas, in this case. The goal of this study is to predict chan...

FE - Ostatní obory vnitřního lékařství

  • 2007 - 2009
  • 5 129 tis. Kč
  • 5 129 tis. Kč
  • MZ
Project

Examination of antioxidant status and some polymorphisms of paraoxonase1 in patients with different diseases of pancreas (NS9769)

The investigation of influences of different diseases of pancreas (acute and chronic pancreatitis, carcinoma of pancreas) on the antioxidant state of patients with the diseases of pancreas and examination of the possibiliti...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2008 - 2011
  • 6 081 tis. Kč
  • 6 081 tis. Kč
  • MZ
Project

Indication and need of pancreas transplantation from the point of view of its impact on organ complications of diabetes and quality of life (ND5295)

The effect of normal glucose metabolism following pancreas transplantation on microvascular complications of diabetes will be observed with the aim to establish indications for isolated pancreas transplantation in hyperlabile type-1...

FJ - Chirurgie včetně transplantologie

  • 1999 - 2001
  • 3 177 tis. Kč
  • 3 177 tis. Kč
  • MZ
Project

Posttransplant function of ischemically impaired organs (pancreas, kidney, islets) preserved by oxygenated perfluorocarbon (PFC). (NR9383)

The aim of this project is to improve the function of transplanted ischemically impaired organs (kidney, pancreas, islets) by storage in oxygenated perfluorocarbon in a rat model using so called two-layer method for cold storage.......

FJ - Chirurgie včetně transplantologie

  • 2007 - 2009
  • 3 306 tis. Kč
  • 3 289 tis. Kč
  • MZ
Project

Pancreas transplantation with enteric drainage (ND6806)

The history of pancreas transplantation is characterized by search for optimal surgical technique of external pancreatic secretion draining. The re-discovered technique if duodenal segment anastomosed to the recipient intestine eliminates so...

FJ - Chirurgie včetně transplantologie

  • 2001 - 2003
  • 1 124 tis. Kč
  • 1 050 tis. Kč
  • MZ
Project

Interplay between ISLET1 and NEUROD1 in pancreatic development and disease (GA19-07378S)

or dysfunction of the insulin-secreting β cells of the pancreas. The most critical step is the identification of molecular cues that specify cellular phenotype in the pancreas and can in the adult pancreas.......

Physiology (including cytology)

  • 2019 - 2022
  • 9 516 tis. Kč
  • 9 516 tis. Kč
  • GA ČR
Project

The effect of simultaneous pancreas and kidney transplantation with long term normoglycemia on small fibre diabetic neuropathy (NR7929)

Diabetic neuropathy is caused by long-term hyperglycemia and affects nerve fibres of various types. Small fibre neuropathy may be assessed by epidermal nerve fibre counts in skin biopsies. The aim of the project is the longitudinal follow-up of the e...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2004 - 2007
  • 2 229 tis. Kč
  • 1 944 tis. Kč
  • MZ
Project

Transplantation of insulin producing tissue generated from adult pancreatic stem cells (NS9712)

The aim of the project is a stem or progenitor cells isolation from adult pancreas tissue and the characterization of these cells, which are able to create an insulin producing tissue. Their features will be tested in vitro as well as after ...

FJ - Chirurgie včetně transplantologie

  • 2008 - 2011
  • 4 676 tis. Kč
  • 4 492 tis. Kč
  • MZ
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