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12 (0,08s)

Project

Localization diagnostics of pancreatic islet-cell tumors. (IZ2949)

FJ - Chirurgie včetně transplantologie

  • 1995 - 1997
  • 330 tis. Kč
  • 330 tis. Kč
  • MZ
Project

Differential diagnostics of the pancreatic diseases.Clinical and pathomorphological study (IZ3777)

FJ - Chirurgie včetně transplantologie

  • 1996 - 1998
  • 838 tis. Kč
  • 752 tis. Kč
  • MZ
Project

Deltins - a population of new proteins and peptides of the GEP-endocrine system and of the CNS. Deltanoma - anew type of the islet cell tumor of the pancreas wi (IZ3695)

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 1996 - 1998
  • 1 392 tis. Kč
  • 1 170 tis. Kč
  • MZ
Project

Pancreas transplantation with enteric drainage (ND6806)

The history of pancreas transplantation is characterized by search for optimal surgical technique of external pancreatic secretion draining. The re-discovered technique if duodenal segment anastomosed to the recipient intestine eliminates some drawba...

FJ - Chirurgie včetně transplantologie

  • 2001 - 2003
  • 1 124 tis. Kč
  • 1 050 tis. Kč
  • MZ
Project

Early antibiotic treatment of acute pancreatitis modulating the course and infectious complications (NL5307)

The main of the study is to establish,in a prospective randomized study, the importance of preventive antibiotic treatment in modulating the course of severe acute pancreatitis. The main criterion of the efficacy of antibiotic therapy will be, in add...

FJ - Chirurgie včetně transplantologie

  • 1999 - 2001
  • 1 164 tis. Kč
  • 1 164 tis. Kč
  • MZ
Project

Indication and need of pancreas transplantation from the point of view of its impact on organ complications of diabetes and quality of life (ND5295)

The effect of normal glucose metabolism following pancreas transplantation on microvascular complications of diabetes will be observed with the aim to establish indications for isolated pancreas transplantation in hyperlabile type-1 diabetic patienst...

FJ - Chirurgie včetně transplantologie

  • 1999 - 2001
  • 3 177 tis. Kč
  • 3 177 tis. Kč
  • MZ
Project

Pancreatic islets transplantation into the subcutaneous pouch - a preclinical study (NV16-28249A)

Transplantation of isolated pancreatic islets is limited by low efficiency of islet isolation from cadaveric pancreases as well as by an insufficient islet engraftment after its infusion into the portal vein of diabetic recipient. It is therefore nec...

FJ - Chirurgie včetně transplantologie

  • 2016 - 2020
  • 7 610 tis. Kč
  • 7 550 tis. Kč
  • MZ
Project

Prediction of gestational diabetes on the basis of steroid metabolism (NV17-30528A)

Gestational diabetes mellitus (GDM) is a frequent complication. We have previously investigated the role of candidate genes and their genetic variability in the pathophysiology of GDM. The obtained data and current knowledge showing an expression of ...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2017 - 2021
  • 11 201 tis. Kč
  • 11 154 tis. Kč
  • MZ
Project

The use of pancreatic islet extracellular matrix for propagation and controlled differentiation of insulin producing cells (GA19-07661S)

Pancreatic islet transplantation into the liver represents an established treatment for patients with type 1 diabetes suffering from hypoglycemia unawareness syndrome. Several important factors hamper its wider use including unsatisfactory local cond...

Endocrinology and metabolism (including diabetes, hormones)

  • 2019 - 2022
  • 9 458 tis. Kč
  • 9 458 tis. Kč
  • GA ČR
Project

Development of ex-vivo cellular models for pancreatic adenocarcinoma markers and targets for precision medicine (NU23-08-00241)

Pancreatic ductal carcinoma (PDAC) is a malignancy with dismal prognosis and limited therapeutic options. Overall survival is significantly limited by the late diagnosis, high metastatic rate of cancer cells and resistance to cytostatic therapy. The ...

Cell biology

  • 2023 - 2026
  • 9 912 tis. Kč
  • 9 912 tis. Kč
  • MZ
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