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4 (0,073s)

Project

Familial aggregation of neurodegenerative parkinsonism with dementia in Czech Republic-clinical, molecular - genetic and morphological study (HORPARK) (NV15-32715A)

An epidemiological study conducted over the last four years revealed an increased prevalence of neurodegenerative parkinsonism with dementia in a specific, isolated region in South-eastern Moravia. A detailed genealogical examination in all positive ...

FH - Neurologie, neurochirurgie, neurovědy

  • 2015 - 2018
  • 3 649 tis. Kč
  • 3 649 tis. Kč
  • MZ
Project

Smart Speech Biomarkers for Parkinson’s Disease and Other Synucleinopathies (NU20-08-00445)

The early recognition of Parkinson’s disease (PD) and other synucleinopathies in prodromal stages has crucial implications for the future development of neuroprotective therapy. With no validated diagnostic biomarker, there is no way to identify peop...

Clinical neurology

  • 2020 - 2024
  • 15 479 tis. Kč
  • 15 467 tis. Kč
  • MZ
Project

NEURODEGENERATIVE PROCESSES IN PATIENTS EXPOSED TO METHANOL PROSPECTIVE STUDY AFTER CZECH MASS METHANOL POISONING OUTBREAK IN 2012 (NV16-27075A)

Certain evidence exists about the role of environmental exposures in neurodegenerative diseases. Methanol is widely spread toxic alcohol with high rate of mortality and nervous system damage. Because it is not toxic for lab animals, human studies are...

FH - Neurologie, neurochirurgie, neurovědy

  • 2016 - 2019
  • 8 386 tis. Kč
  • 8 386 tis. Kč
  • MZ
Project

Endemic parkinsonism in South-eastern Moravia and its pathophysiology epidemiological, genetical and environmental comparative study (NW25-04-00194)

The proposed project will focus on research of the mutual relationship between genetic and environmental risk factors; their joint impact is presumed to be the principal risk factor of the high prevalence of neurodegenerative parkinsonism in one of t...

Clinical neurology

  • 2025 - 2028
  • 17 143 tis. Kč
  • 17 143 tis. Kč
  • MZ
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