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1 859 (0,269s) •

Project

Vector-free transmission of Lyme borreliosis spirochetes (GA25-17301S)

Transmission of tick-borne pathogens is, clearly, via ticks. Lyme borreliosis vectors or other routs of spirochete transmission. Even a minor component of the pathogen transmission managed without involvem...

Zoology

  • 2025 - 2027
    • •
  • 9 159 tis. Kč
    • •
  • 9 159 tis. Kč
    • •
  • GA ČR
Project

Investigating the role of tick salivary protease inhibitors at the interface between ticks, pathogens and the vertebrate host (GAP502/12/2409)

hemisphere. Upon pathogen transmission, tick salivary protease inhibitors play a role the transmission of tick-borne pathogens, however, remains elusive. Our interdisciplinary inhibitors during pathogen <...

EB - Genetika a molekulární biologie

  • 2012 - 2015
    • •
  • 11 756 tis. Kč
    • •
  • 8 956 tis. Kč
    • •
  • GA ČR
Project

Tick saliva-activated transmission of important pathogens (GA524/05/0811)

Tick saliva has been proven to facilitate transmission of important human pathogens via the actions of bioactive molecules on the vertebrate host. Although several candidate molecules for this saliva-activated transmission ...

EC - Imunologie

  • 2005 - 2007
    • •
  • 2 850 tis. Kč
    • •
  • 2 850 tis. Kč
    • •
  • GA ČR
Project

Revision of Borrelia afzelii transmission cycle essential step for Lyme disease interventions (GA17-27393S)

transmission is the development of a vaccine affecting molecular interactions between tick and transmitted spirochetes. Till very recently, there were no reliable transmission models for tick-borne pathogens from naturally...

EE - Mikrobiologie, virologie

  • 2017 - 2019
    • •
  • 5 809 tis. Kč
    • •
  • 5 647 tis. Kč
    • •
  • GA ČR
Project

Effect of tick saliva on the transmission of Borrelia burgdorferi (GA524/02/0901)

against tick-transmitted pathogens. The aim of the project is to demonstrate the promotion of the transmission of an important human pathogen Borrelia burgdorferi effects, facilitate not only tick feeding on the host, but ...

EC - Imunologie

  • 2002 - 2004
    • •
  • 3 340 tis. Kč
    • •
  • 2 540 tis. Kč
    • •
  • GA ČR
Project

Serpins from the salivary glands of Lyme disease vector, the tick Ixodes ricinus, and their role in the tick-host-pathogen interaction (GJ16-07117Y)

host defense mechanisms and can facilitate pathogen transmission. In this project interaction and pathogen transmission. To this end, recombinant serpins, including tick......

EB - Genetika a molekulární biologie

  • 2016 - 2020
    • •
  • 5 616 tis. Kč
    • •
  • 5 616 tis. Kč
    • •
  • GA ČR
Project

The effect of tick saliva on the transmission of the Lyme disease causative agent Borrelia burgdorferi (GA524/99/D035)

effects, facilitates both tick feeding on and transmission of pathogens the effect of saliva on immunity to tick-transmitted pathogens. The aim of the project is to demonstrate the impact of tick saliva on the transmis...

EC - Imunologie

  • 1999 - 2002
    • •
  • 298 tis. Kč
    • •
  • 298 tis. Kč
    • •
  • GA ČR
Project

Molecular epidemiology of emerging infectious diseases. (MEB021130)

The aim of the project is to analyse the relationships between the genetic variation of innate immunity genes and sensitivity to pathogens of wild rodents. Studied pathogens are transmissible among animals and human and may...

EC - Imunologie

  • 2011 - 2011
    • •
  • 66 tis. Kč
    • •
  • 66 tis. Kč
    • •
  • MŠMT
Project

Identification and characterization of the tick salivary glands and midgut molecules involved in the interaction with pathogens (GA17-27386S)

. Balancing of the mutual interactions between the pathogens and ticks is crucial for the pathogen acquisition and transmission. However, molecules involved in the crosstalk to assess their involvement in the tick feeding a...

ED - Fyziologie

  • 2017 - 2019
    • •
  • 5 728 tis. Kč
    • •
  • 5 566 tis. Kč
    • •
  • GA ČR
Project

The role of tick organs in the transmission of Borrelia afzelii spirochetes (GA22-30920S)

the salivary route of Borrelia transmission had rather a weak effect. Our recent study. afzelii transmission. The next goal is to identify novel vaccination targets that are indispensable for B. afzelii survival and transmissio...

Microbiology

  • 2022 - 2025
    • •
  • 9 049 tis. Kč
    • •
  • 9 049 tis. Kč
    • •
  • GA ČR
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