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1 242 (0,123s) •

Project

Pathological expansion of microsatellites in the human genome. (NR9147)

to the pathological expansions.1, Identification of regions in the human genome most prone to expansion to expansion. 3, Biophysical analysis of the expanding fragments to identify DNA secondary structures partici...

EB - Genetika a molekulární biologie

  • 2007 - 2009
    • •
  • 2 336 tis. Kč
    • •
  • 2 336 tis. Kč
    • •
  • MZ
Project

Development of a method for prediction of pathological expansions of trinucleotide repeats in the human genome (NM7634)

that the common PCR in vitro simulates the pathological microsatellite expansions in the human pathologically expanding human genome regions. Generalize the results into rules precting propensity to the expansion ...

EB - Genetika a molekulární biologie

  • 2003 - 2005
    • •
  • 4 688 tis. Kč
    • •
  • 2 063 tis. Kč
    • •
  • MZ
Project

Structural properties and expansion of mononucleotide and dinucleotide microsatellites of the human genome (GA301/01/0590)

We propose to test a hypothesis that pathological expansions of microsatellites in genomes can be simulated by PCR of short DNA fragments. For this purpose: (i) We will do PCR experiments with a set of DNA fragments containing dinuc...

EB - Genetika a molekulární biologie

  • 2001 - 2003
    • •
  • 4 249 tis. Kč
    • •
  • 2 149 tis. Kč
    • •
  • GA ČR
Project

Computer analysis of microsatellite expansion in the human genome. (GA302/97/0313)

Eucaryotic genomes contain hundreds of thousands of microsatellite sequences whose expansion above a critical lenght,cause serious diseases in some cases.In and mechanisms of the microsatellite expansion and, maybe, of the circumsta...

EB - Genetika a molekulární biologie

  • 1997 - 1998
    • •
  • 1 046 tis. Kč
    • •
  • 821 tis. Kč
    • •
  • GA ČR
Project

Research and development of medical devices at Contipro a.s. for the treatment and prevention of pathological conditions associated with tooth extraction (EI24_063/0006634)

and prevention of pathological conditions in dentistry. Within the project, three functional of these pathologies. The applicant is a small company with medium market capitalization, Contipro for these pathologies, offerin...

Biomaterials (as related to medical implants, devices, sensors)

  • 2025 - 2028
    • •
  • 39 005 tis. Kč
    • •
  • 0 tis. Kč
    • •
  • MPO
Project

Cardiac pathology. Pathology of infectious endocarditis. Pathology of coronary veins in ischemic heart disease. Pathology of cardiac surgery. (IZ1179)

9F - 9

  • 1992 - 1994
    • •
  • 0 tis. Kč
    • •
  • 0 tis. Kč
    • •
  • MZ
Project

Exploring the impact of somatic expansion rates on quantitative progression marker candidates (Voice) in early stages of Repeat Expansion Disorders (9F25002)

repeat expansion mutations at early disease stages/prodromal (within 5 years, and somatic expansion index and somatic expansion rate Aim 2: Study longitudinally and somatic expansion rate Aim 3: Analyze the cor...

Clinical neurology

  • 2025 - 2028
    • •
  • 6 206 tis. Kč
    • •
  • 6 206 tis. Kč
    • •
  • MŠMT
Project

Bronchoscopical evaluation of the risk of the damage to the respiratory system in children with perinatal pathology (NE4574)

Assesment of the value of endobronchial pathology monitored by the ultrathin fiberoptic bronchoscopy for guiding the therapy and evaluation of the prognosis of persisting respiratory pathology in children in the perinatal intensive ...

FG - Pediatrie

  • 1998 - 2000
    • •
  • 1 678 tis. Kč
    • •
  • 1 455 tis. Kč
    • •
  • MZ
Project

Conformational polymorphism and expansion fo the (CNG)n and related microsatellite DNA sequences (GA204/98/1027)

Conformational polymorphism is a likely cause of microsatellite expansions in genomes. In some cases the expansions result in serious, mainly neurodegenerative, and correlate the conformational properties with the oligonucleotide

EB - Genetika a molekulární biologie

  • 1998 - 2000
    • •
  • 2 404 tis. Kč
    • •
  • 1 775 tis. Kč
    • •
  • GA ČR
Project

*Research and development of application compress natural gas energy potential during expansion in control station for production of electric energy in expansion turbine. (FI-IM3/047)

*Research and development of regulation equipments, whose main part is the expansion turbine. These equipments exploit energy potential of compress natural gas during expansion in control station for production of eletric energy. Th...

JE - Nejaderná energetika, spotřeba a užití energie

  • 2006 - 2009
    • •
  • 9 979 tis. Kč
    • •
  • 5 429 tis. Kč
    • •
  • MPO
  • 1 - 10 out of 1 242