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58 (0,07s) •

Project

Study of phosphonate behavior to reduce losses in plant products (TJ04000245)

The project is focused on the occurrence of phosphonates in pome fruits in real samples and monitoring of phosphonates (Fosetyl-Al - sum of fosetyl, phosphonic acid and their salts, expressed as fosetyl) in various parts of...

Analytical chemistry

  • 2020 - 2022
    • •
  • 9 174 tis. Kč
    • •
  • 6 485 tis. Kč
    • •
  • TA ČR
Project

Preparation of inorganic-organic hybrid materials based on layered phosphonates (GP203/06/P127)

will serve as starting compounds for the synthesis of layered metal phosphonates and chemical properties of the layered materials prepared from the phosphonic acids. The work will focus on a synthesis of phosphonic acids w...

CA - Anorganická chemie

  • 2006 - 2008
    • •
  • 360 tis. Kč
    • •
  • 360 tis. Kč
    • •
  • GA ČR
Project

Phosphonate biosynthesis and degradation – a novel mitochondrial pathway involved in global phosphorus turnover? (GM21-19798M)

as phosphonates, whose metabolism has only been thoroughly studied in bacteria. We identified unexpectedly widespread phosphonate enzymes in eukaryotic genomes and predict phosphonate enzyme distribution, expression, and c...

Microbiology

  • 2021 - 2025
    • •
  • 21 111 tis. Kč
    • •
  • 21 111 tis. Kč
    • •
  • GA ČR
Project

Reactions of Phosphates and Phosphonates with Organotitanium(IV) Fluorides and Alkoxides (MEB091018)

Metallophosphates and -phosphonates attracted considerable interest in the area, photochemistry, and materials chemistry. Most of the metal phosphonates possess two- or three will concentrate on titanium phosphates and phosphona...

CA - Anorganická chemie

  • 2010 - 2011
    • •
  • 112 tis. Kč
    • •
  • 112 tis. Kč
    • •
  • MŠMT
Project

Phosphonate-based 2'-5' oligoadenylate analogs a novel metabolically stable potential activators of RNase L. (IAA4055101)

The project is aimed towards the synthesis of a unique set of structurally diverse phosphonate 2',5'-oligoadenylate (2-5A) analogs as potential activators oligomerzation of activated phosphonate monomers in solution leading to the p...

CC - Organická chemie

  • 2001 - 2005
    • •
  • 15 202 tis. Kč
    • •
  • 4 405 tis. Kč
    • •
  • AV ČR
Project

Nucleophilic introduction of fluorinated groups using organo-phosphorus compounds (GP203/08/P310)

The grant proposal is focused on the investigation of fluorinated phosphonates such as diethyl trifluoromethyl phosphonate, diethyl difluoromethyl phosphonate and tetraethyl fluoromethylenediphosphonate for the nucleophilic...

CC - Organická chemie

  • 2008 - 2010
    • •
  • 1 188 tis. Kč
    • •
  • 1 188 tis. Kč
    • •
  • GA ČR
Project

Properties of α-D- and α-L-Oligodeoxynucleotides with Isopolar Phosphonate Internucleotide Linkages (GA17-12703S)

The project is focused on the synthesis of new types of nuclease stable antisense compounds based on structurally diverse phosphonate alpha-D- and alpha-L-oligodeoxynucleotides with preorganized modified sugar-phosphate backbone, targeted to...

CC - Organická chemie

  • 2017 - 2021
    • •
  • 7 824 tis. Kč
    • •
  • 5 325 tis. Kč
    • •
  • GA ČR
Project

Modified oligonucleotides derived from 5´-substituted nucleoside 5´-C-phosphonates synthesis and hybridization properties (GP203/04/P273)

Modified oligonucleotides containing the 3´-O-P-CH(R)-5´´ internucleotide linkages derived from 5´-substituted nucleoside 5´-C-phosphonates in the project´- and 5´-substituted 5´-C-phosphonate analogues which will be tested, as a sm...

CC - Organická chemie

  • 2004 - 2006
    • •
  • 806 tis. Kč
    • •
  • 806 tis. Kč
    • •
  • GA ČR
Project

Anomeric D- and L-oligonucleotides with isopolar, isosteric internucleotide linkage Synthesis, hybridization properties and spectroscopy (IAA4055902)

Project is directed towards synthesis of isopolar, isosteric phosphonate analogs of nucleotides and oligonucleotides based on them which contain enzyme-stable internucleotice bond, attention being paid to some specific properties of oligonuc...

CC - Organická chemie

  • 1999 - 2001
    • •
  • 5 127 tis. Kč
    • •
  • 2 445 tis. Kč
    • •
  • AV ČR
Project

Novel oligonucleotides containing nonisosteric, enzyme-stable phosphonate linkages systematic physico-chemical study on structure variants (GA203/01/1166)

The project is directed towards a thorough study on the synthesis and physico-chemical investigation of isopolar, nonisosteric, adenine-containing dinucleoside monophosphate and oligothymidylate analogs with the enzymatically stable phosphonate

CC - Organická chemie

  • 2001 - 2003
    • •
  • 8 501 tis. Kč
    • •
  • 4 537 tis. Kč
    • •
  • GA ČR
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