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*Investigation of novel formulations of gels containing liposomes fused wiht hydrophobic microparticles of phtalocyanine for photodynamic therapy of tumors (2A-1TP1/026)
*Investigate formulations; means of stabilization of gel containing liposomes and hydrophobic phtalocyanine; preclinically test its efficiency on various tumor types and till stage 2B clinically test this new drug form for photodynamic
FR - Farmakologie a lékárnická chemie
- 2006 - 2011 •
- 19 703 tis. Kč •
- 13 598 tis. Kč •
- MPO
Řešení projektu: 15. 11. 2006 - 31. 12. 2011
Uznané náklady
Podpora ze státního rozpočtu (69%)
Poskytovatel: Ministerstvo průmyslu a obchodu
Liposomal photodynamic therapy of tumors (NC4810)
Utilization of liposomal preparations for selective distribution of hydrophobic photosensitiers to tumor cell membranes will enhance efficiency of photodynamic therapy of tumor diseases and simultaneously will elim...
FD - Onkologie a hematologie
- 1998 - 2000 •
- 1 469 tis. Kč •
- 1 243 tis. Kč •
- MZ
Řešení projektu: 1. 1. 1998 - 1. 1. 2000
Uznané náklady
Podpora ze státního rozpočtu (85%)
Poskytovatel: Ministerstvo zdravotnictví
Experimental photodynamic therapy of tumore with employment of liposomal forms of novel photosenzitizers (NC6564)
Development and testing of liposomal forms of various photosenzitizers, eg.meso-tetrakis/phenylporphine (TPP), in order to obtain the highly efficient form for photodynamic therapy of tumors. The basic test will lie in the ...
FD - Onkologie a hematologie
- 2001 - 2003 •
- 4 389 tis. Kč •
- 2 021 tis. Kč •
- MZ
Řešení projektu: 1. 1. 2001 - 1. 1. 2003
Uznané náklady
Podpora ze státního rozpočtu (46%)
Poskytovatel: Ministerstvo zdravotnictví
Technology for photodynamic therapy of tumors (OE09026)
for photodynamic therapy (PDT) of tumors based on hyhobic derivatives of phtalocyanines of photosensitizers and new light sources for the photodynamic therapy of tumours. AIMS A) We for the photodynam...
FR - Farmakologie a lékárnická chemie
- 2009 - 2012 •
- 25 545 tis. Kč •
- 12 000 tis. Kč •
- MŠMT
Řešení projektu: 1. 4. 2009 - 31. 12. 2012
Uznané náklady
Podpora ze státního rozpočtu (47%)
Poskytovatel: Ministerstvo školství, mládeže a tělovýchovy
Complex liposomal forms of photosentitizers for experimental photodynamic therapy of tumors (NR7778)
We propose to develop and test, by experimental photodynamic therapy (PDT) of human tumors, the liposomal gel forms containing various hydrophobic, in order to reach approval for clinical testing. Depth profile of healing <...
FD - Onkologie a hematologie
- 2004 - 2009 •
- 8 383 tis. Kč •
- 4 651 tis. Kč •
- MZ
Řešení projektu: 1. 1. 2004 - 31. 12. 2009
Uznané náklady
Podpora ze státního rozpočtu (55%)
Poskytovatel: Ministerstvo zdravotnictví
Synthetic probes for recognition of tumor markers applications for cell directed apoptosis and targeted photodynamic therapy (GA203/09/1311)
and targeted photodynamic therapy (PDT). The proposed concept is based on several binding motifs for tumor markers, specifically porphyrins, calixphyrins, bicyclic guanidines and elimination of tumors by means of ...
CC - Organická chemie
- 2009 - 2012 •
- 4 776 tis. Kč •
- 4 744 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2009 - 31. 12. 2012
Uznané náklady
Podpora ze státního rozpočtu (99%)
Poskytovatel: Grantová agentura České republiky
Novel photosensitizers for vascular targeted photodynamic therapy (GJ19-14758Y)
Tumorous diseases are among leading causes of death in developed countries. Research in the field of novel approaches and compounds with potential to be efficient drug is therefore eligible. Vascular targeted photodynamic therap...
Medicinal chemistry
- 2019 - 2022 •
- 5 215 tis. Kč •
- 5 209 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2019 - 30. 6. 2022
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Industrial microfluidization of liposomal and hydrophobic drug formulations (TA01010781)
-aluminum phthalocyanine, already patented in its laboratory form for photodynamic therapy of tumors in dermatology, head and neck cancer and for colorectal carcinoma will be developed and resulting preparations will be tes...
FR - Farmakologie a lékárnická chemie
- 2011 - 2016 •
- 44 950 tis. Kč •
- 33 513 tis. Kč •
- TA ČR
Řešení projektu: 1. 1. 2011 - 31. 12. 2016
Uznané náklady
Podpora ze státního rozpočtu (75%)
Poskytovatel: Technologická agentura ČR
Combination of High Power Lasers and Photodynamic Therapy in Head and Neck Oncology (NR8390)
, hyperthermy and photodynamic therapy. This combination can be used as tool for complete with results of conventional therapy. The planned result can be a new algoritmus for complex oncologic therapy than conventi...
FD - Onkologie a hematologie
- 2005 - 2007 •
- 3 508 tis. Kč •
- 3 507 tis. Kč •
- MZ
Řešení projektu: 1. 1. 2005 - 31. 12. 2007
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Photodynamic therapy of tumors (GA312/96/0518)
Photodynamic therapy (PDT) is a new method to cure tumors which is based upon activation of photosensitizer selectively accumulated in the tumour tissue. Activation by a suitable light source is causing necrosis of the tumo...
BO - Biofyzika
- 1996 - 1998 •
- 4 355 tis. Kč •
- 4 247 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 1996 - 1. 1. 1998
Uznané náklady
Podpora ze státního rozpočtu (98%)
Poskytovatel: Grantová agentura České republiky
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