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Projects

67 projects (0,111s) •

Project

Pituitary adenomas in tissue culture The influence of somastotatin analogs and inductors of apoptosis. (NB6172)

The study of the influence of somatostatin analoques various somatostatin receptor subtypes on the secretion of pituitary adenoma explants in vitro. The induction of apoptosis of pituitary cell lines by these analoques, hyp...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2000 - 2002
    • •
  • 4 139 tis. Kč
    • •
  • 1 661 tis. Kč
    • •
  • MZ
Project

Quantitative analysis of somatostatin receptors in pituitary adenomas. (NT11344)

The aim of the study is quantitative analysis of somatostatin receptors expression in pituitary tumours and correlation of receptors expression profile with clinical and laboratory data. The second goal is to introduce PCR analysis for medic...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2010 - 2013
    • •
  • 2 704 tis. Kč
    • •
  • 2 704 tis. Kč
    • •
  • MZ
Project

MRI diagnostic markers in Cushing´s disease (NT13631)

Strategy and clinical results of ACTH pituitary adenoma resection are influenced by preoperative magnetic resonance imaging (MRI).Conventional MRI, however and optimized sequence to determine the localization of pituitary <...

FH - Neurologie, neurochirurgie, neurovědy

  • 2012 - 2015
    • •
  • 3 243 tis. Kč
    • •
  • 3 075 tis. Kč
    • •
  • MZ
Project

Immunohistochemistry of pituitary adenomas (IZ2974)

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 1995 - 1998
    • •
  • 633 tis. Kč
    • •
  • 633 tis. Kč
    • •
  • MZ
Project

Morphological and functional analysis of pituitary adenomas structure prediction and postoperative changes in nasal airflow and olfactory function (NW24-08-00324)

Pituitary adenoma surgery was recently subject to a major transformation due to the advent of endoscopic techniques bringing new challenges in surgical planning and complications management. First section of this project focuses on ...

Neurosciences (including psychophysiology)

  • 2024 - 2027
    • •
  • 11 705 tis. Kč
    • •
  • 11 705 tis. Kč
    • •
  • MZ
Project

Internexin-alpha in aggressive/fast- and slow growing clinically non-functioning pituitary adenomas (NV19-01-00435)

Neurosurgical procedure often does not lead to complete removal of non-functioning pituitary macroadenoma (NFPA). However, a persuasive marker for assessing relapse / growth risk of residuum has not yet been discovered. Internexin-alpha (INA...

Endocrinology and metabolism (including diabetes, hormones)

  • 2019 - 2022
    • •
  • 8 907 tis. Kč
    • •
  • 8 907 tis. Kč
    • •
  • MZ
Project

Increase of extent pituitary adenomas endoscopic endonasal resection by application of intraoperative MRI and the risk of development of postoperative hypopituitarism (NT14256)

Sellar region tumors represent app. 20% of intracranial tumors. These tumors are benign in the majority of cases. Transsphenoidal surgery is indicated in the vast majority of these cases. Transcranial surgeries are performed rarely. The goal of the s...

FH - Neurologie, neurochirurgie, neurovědy

  • 2013 - 2015
    • •
  • 2 606 tis. Kč
    • •
  • 2 606 tis. Kč
    • •
  • MZ
Project

Comparation study of the serum and tissue cytokines level before and after parathyroidectomy for parathyroid adenoma and hyperplastic parathyroid glands (NK6023)

Comparasion serum and tissue TGF alpha,bFGF,IGF,IGF-I and TNF alpha and IL-6 before and after parathyroidectomy for parathyroid adenoma and hyperplastic parathyroid gland.......

FF - ORL, oftalmologie, stomatologie

  • 2000 - 2002
    • •
  • 2 597 tis. Kč
    • •
  • 2 597 tis. Kč
    • •
  • MZ
Project

Evo-devo of the vertebrate pituitary on trial pharyngeal and secretory proto-pituitary gland in basal fish embryos (GA25-17860S)

The pituitary is a master endocrine gland of vertebrates with many long revives classic theories that pituitary evolved through interactions with pharyngeal-derived proto-pituitary, with possibly exocrine functions as in am...

Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology

  • 2025 - 2027
    • •
  • 8 397 tis. Kč
    • •
  • 8 397 tis. Kč
    • •
  • GA ČR
Project

Detection of mutation in MLH1, MSH2 and APC genes in the sporadic colorectal adenomas (NK7270)

Immunohistochemistry is a new method for detection of the loss of expression of MLH1, MSH2 and APC genes. The aim of the study is to determine the frequency of mutations in the genes mentioned above in soradic colorectal adenomas using this ...

FE - Ostatní obory vnitřního lékařství

  • 2002 - 2004
    • •
  • 1 445 tis. Kč
    • •
  • 1 426 tis. Kč
    • •
  • MZ
  • 1 - 10 out of 67