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77 (0,1s) •

Project

Plasmid innovation - the interaction of resistance and virulence plasmids (GAP502/12/1467)

to multidrug resistance encoded by R-plasmids. Furthermore, a new next step in bacterial plasmid evolution is the recombination of R-plasmids with plasmids increasing with the following main objectives i) to test ...

EB - Genetika a molekulární biologie

  • 2012 - 2016
    • •
  • 3 526 tis. Kč
    • •
  • 3 526 tis. Kč
    • •
  • GA ČR
Project

Evolutionary trade-offs of plasmid-carried antibiotic resistance in clinically relevant pathogens (GA24-12527S)

Plasmids play a key role in the evolution of antimicrobial resistant bacteria). Although plasmids provide bacteria with antimicrobial resistance (AMR) and many other, some AMR plasmid-bacterium associations became particula...

Microbiology

  • 2024 - 2026
    • •
  • 11 985 tis. Kč
    • •
  • 11 985 tis. Kč
    • •
  • GA ČR
Project

Treatment of experimental neuropathies by VEGF and NGF gene transfer (ME 831)

preparation of plasmids wuth VEGF 165 and beta-NGF C DNA, optimal dosage of plasmids, monitoring of regenerative capability...

FH - Neurologie, neurochirurgie, neurovědy

  • 2006 - 2009
    • •
  • 4 743 tis. Kč
    • •
  • 2 421 tis. Kč
    • •
  • MŠMT
Project

Sentinel testing survey of plasmid-mediated (transferable) colistin resistance among Enterobacteriaceae in the Czech Republic (NV18-09-00254)

The proposed one health approach project is the sentinel testing survey of the occurrence of Enterobacteriaceae with plasmid-mediated transferable resistance to colistin ( a reserve antibiotic used in human medicine but also in the veterinar...

Epidemiology

  • 2018 - 2021
    • •
  • 10 491 tis. Kč
    • •
  • 10 491 tis. Kč
    • •
  • MZ
Project

Epidemic antibiotic resistance plasmids - evolution, plasticity and fitness (GJ15-14683Y)

of epidemic plasmids associated with resistance to clinically important cephalosporins. Structure, plasticity and evolution of the epidemic plasmids as well as their potential will be studied. The role of additional accessory mecha...

EB - Genetika a molekulární biologie

  • 2015 - 2017
    • •
  • 7 621 tis. Kč
    • •
  • 7 621 tis. Kč
    • •
  • GA ČR
Project

Multiresistant high-risk Escherichia coli lineages a success story of the chromosome and plasmid interplays (GA18-23532S)

of antibiotic resistance, virulence and specific plasmids will be evaluated. The role of plasmids, their stability, transfer and relationships with bacterial genome will be studied. Interplays between plasmid and genome of...

Microbiology

  • 2018 - 2020
    • •
  • 10 660 tis. Kč
    • •
  • 10 660 tis. Kč
    • •
  • GA ČR
Project

Molecular mechanism of regulation of expression of the chromosomal and plasmid genes from coryneform bacteria (GA204/97/0528)

studied. In the part of the project focused on regulation of plasmid pGA1genes we, the key role will be played by the positively acting regulator of plasmid copy number named Per, which is a completely novel element in plasmid<...

EB - Genetika a molekulární biologie

  • 1997 - 1999
    • •
  • 3 681 tis. Kč
    • •
  • 2 260 tis. Kč
    • •
  • GA ČR
Project

Transformation system for rumen anaerobic bacterium Butyrivibrio fibrisolvens (IBS5045112)

The project proposal is based on a construction of a plasmid transformation system for anaerobic microorganisms present in the digestive tract of ruminants. We have selected for this purpose rumen bacterium Butyrivibrio fibrisolvens which we...

GJ - Choroby a škůdci zvířat, veterinární medicina

  • 2001 - 2005
    • •
  • 2 364 tis. Kč
    • •
  • 1 125 tis. Kč
    • •
  • AV ČR
Project

Construction of a Plasmid Vector for Anaerobic Bacteria (GA508/93/2485)

9C - 9

  • 1993 - 1995
    • •
  • 183 tis. Kč
    • •
  • 366 tis. Kč
    • •
  • GA ČR
Project

Yeast cytoplasmic viruses and plasmids as models for investigation of cell functions and viruses of higher eukaryotes (GA204/98/1195)

In the course of the suggested project 'Yeast cytoplasmic viruses and plasmids as models for investigation of cell functions and viruses of higher eukaryotes' we Saccharomyces cerevisiae and Endomyces magnusii and cytoplasmic linear dsDNA

EB - Genetika a molekulární biologie

  • 1998 - 2000
    • •
  • 3 491 tis. Kč
    • •
  • 3 037 tis. Kč
    • •
  • GA ČR
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