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Effect of various methods of white blood cell reduction on platelet function and the pro-coagulant activity of platelet concentrates (NC7557)
A white blood cell (WBC) reduction of platelet concentrates and its influence on platelet function and activation of coagulation. A comparison of platelet concentrates prepared by a three commonly used techniques for WBC-re...
FD - Onkologie a hematologie
- 2003 - 2005 •
- 4 258 tis. Kč •
- 4 137 tis. Kč •
- MZ
Řešení projektu: 1. 1. 2003 - 1. 1. 2005
Uznané náklady
Podpora ze státního rozpočtu (97%)
Poskytovatel: Ministerstvo zdravotnictví
PLATELETS - use of cryopreserved platelets for treatment of massive bleeding in combat casualties (OWUVN20170002)
To determine the optimal manufacturing process of cryopreserved platelets, reconstitution and use of cryopreserved platelets in clinical use and in the field, based the quality parameters of cryopreserved platelets after th...
KA - Vojenství
- 2017 - 2019 •
- 8 833 tis. Kč •
- 8 833 tis. Kč •
- MO
Řešení projektu: 2. 1. 2017 - 31. 12. 2019
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo obrany
The effect of oxidation stress on the properties of human blood platelets (NK4809)
The study of oxidative stress effect on human blood platelets in platelet concentrates stored at various conditions and on platelets of patients overloaded with iron. The effect of oxido-reduction state of latelet concentra...
FP - Ostatní lékařské obory
- 1998 - 2000 •
- 4 021 tis. Kč •
- 3 267 tis. Kč •
- MZ
Řešení projektu: 1. 1. 1998 - 1. 1. 2000
Uznané náklady
Podpora ze státního rozpočtu (81%)
Poskytovatel: Ministerstvo zdravotnictví
Platelet activity after on-pump versus off-pump coronary artery bypass surgery. Is there a platelet hyperaggregation after off-pump procedures? (NR8526)
early andlate platelet activity in on-pump and off-pump patients. Platelet activity will be measured by the aggregability test and flow cytometry. Hypothesis of platelet higher......
FA - Kardiovaskulární nemoci včetně kardiochirurgie
- 2005 - 2007 •
- 1 276 tis. Kč •
- 1 276 tis. Kč •
- MZ
Řešení projektu: 1. 1. 2005 - 31. 12. 2007
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Influence of oxidative modification of proteins on activation of human blood platelets (NK6841)
mediate platelet function in vitro. The modification of proteins by oxidant species generated during activation of platelets will be detected. LDL from normal donors LDLand Fbg on platelets will be studied using aggregomet...
FP - Ostatní lékařské obory
- 2001 - 2003 •
- 2 178 tis. Kč •
- 2 100 tis. Kč •
- MZ
Řešení projektu: 1. 1. 2001 - 1. 1. 2003
Uznané náklady
Podpora ze státního rozpočtu (96%)
Poskytovatel: Ministerstvo zdravotnictví
Gingival Recession Coverage using Collagen Matrix in Combination with Platelet-Rich Plasma, Platelet-Rich Fibrin, or Enamel Matrix Derivate (NT14321)
The project aims to validate the effect of Platelet-Rich Plasma (PRP), Platelet-Rich Fibrin (PRF) and Enamel Matrix Derivate (Emdogain, EMD) with collagen matrix to increase the formation of keratinized gingiva in an animal model. A...
FF - ORL, oftalmologie, stomatologie
- 2013 - 2015 •
- 7 840 tis. Kč •
- 7 840 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2013 - 31. 12. 2015
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Differences in parameters of platelets aggregation and blood coagulation between healthy individuals and patients with metabolic diseases (NU21J-02-00021)
that these diseases affect also directly platelet aggregation and blood coagulation. In particular sensitivity of platelets from familial hypercholesterolemic patients are already known phenomena. In this study, we aim to analyze <...
Pharmacology and pharmacy
- 2021 - 2024 •
- 6 741 tis. Kč •
- 6 705 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2021 - 31. 12. 2024
Uznané náklady
Podpora ze státního rozpočtu (99%)
Poskytovatel: Ministerstvo zdravotnictví
Posttranslation protein modifications in activated blood platelets (NS10633)
The aim of the project is identication of posttranslation modifications (PTM) in proteins of both activated and non activated platelets with a special fokus on redox-dependent protein modifications. The platelets will be activated b...
FA - Kardiovaskulární nemoci včetně kardiochirurgie
- 2009 - 2011 •
- 6 990 tis. Kč •
- 6 990 tis. Kč •
- MZ
Řešení projektu: 1. 1. 2009 - 31. 12. 2011
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Interactions among collagen, platelets and phagocytes in modulation of reactive oxygen and nitrogen species production (OC10044)
Major hypothesis Platelets, collagen and neutrophils tightly cooperate. Mainobjectives to provide new information on the effects of platelet-derived mediators like and oxidatively modified), platelets and phagocytes under p...
EC - Imunologie
- 2010 - 2011 •
- 742 tis. Kč •
- 742 tis. Kč •
- MŠMT
Řešení projektu: 1. 5. 2010 - 30. 6. 2011
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo školství, mládeže a tělovýchovy
Aspirin resistance in patients with cardiovascular diseasae and changes of thrombocyte function in aspirin non responders, bioindicators of therapy and prognosis of non responders (NR8036)
of two independent methods (platelet aggregation after induction by propyl gallate and assessment of platelet function by PFA 100 method). The second aim of thestudy is to find and acquired platelet dysfunction (examinatio...
FA - Kardiovaskulární nemoci včetně kardiochirurgie
- 2004 - 2006 •
- 1 769 tis. Kč •
- 1 717 tis. Kč •
- MZ
Řešení projektu: 1. 1. 2004 - 1. 1. 2006
Uznané náklady
Podpora ze státního rozpočtu (97%)
Poskytovatel: Ministerstvo zdravotnictví
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