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Project

*Research of technologies and methods of removing heavy metals from the platinum group of biological waste and their recycling options (FR-TI1/494)

*A project proposes a solution for minimization of the content of platinum of this drugs. A regenerated platinum will be a parallel output. A project further proposes a detailed study of platinum drugs fate in environmental...

CE - Biochemie

  • 2009 - 2012
    • •
  • 16 332 tis. Kč
    • •
  • 10 453 tis. Kč
    • •
  • MPO
Project

DNA reactions of aminophoshine platinum(II) compounds. Relations to the development of new platinum antitumor drugs (GA301/98/P231)

This project is aimed at the study of some aspects of molecular mechanism of antitumor activity of selected platinum complexes. For this study, new platinum complexes with amino- phosphine ligands were chosen. These new platinum...

CE - Biochemie

  • 1998 - 2001
    • •
  • 810 tis. Kč
    • •
  • 750 tis. Kč
    • •
  • GA ČR
Project

DNA interactions of the second generation platinum anticancer drugs (IAA7004805)

activity of platinum compounds and is based on recent prograss reached in this field in a fundamental way to development of theoretical background for the synthesis of platinum of cellular resistence to cisplatin (cisplatin is the ...

FR - Farmakologie a lékárnická chemie

  • 1998 - 2001
    • •
  • 4 219 tis. Kč
    • •
  • 2 481 tis. Kč
    • •
  • AV ČR
Project

Interaction of Platinum Pharmacs and Nucleotic Acids and Molecular Identification of Linkage Points (OC D20.005)

Interaction of Platinum Pharmacs and Nucleotic Acids and Molecular Identification of Linkage Points...

FR - Farmakologie a lékárnická chemie

  • 2003 - 2004
    • •
  • 609 tis. Kč
    • •
  • 469 tis. Kč
    • •
  • MŠMT
Project

Platinum Metal Complexes as DNA-Protein Cross-Linking Agents (ME08017)

This project is aimed to find out data on covalent interactions of DNA modified by platinum complexes with proteins....

BO - Biofyzika

  • 2008 - 2010
    • •
  • 2 226 tis. Kč
    • •
  • 2 226 tis. Kč
    • •
  • MŠMT
Project

Platinum complexes of biorelevant sulphur ligands (ME 439)

The study of platinum complexes with sulphur containing ligans is of considerable interest in the contex of the tumor chemotheraphy and certain catalytic processes. Therefore new types of platinum complexes with sulpur containing ch...

CF - Fyzikální chemie a teoretická chemie

  • 2001 - 2002
    • •
  • 440 tis. Kč
    • •
  • 210 tis. Kč
    • •
  • MŠMT
Project

DNA interactions of polynuclear platinum (ME 152)

Dinuclear and trinuclear platinum complexes represent a novel class of antitumor compounds. The development of polynuclear platinum complexes is based platinum complexes. This joint project has been proposed on the basis of...

FR - Farmakologie a lékárnická chemie

  • 1998 - 2000
    • •
  • 5 344 tis. Kč
    • •
  • 2 127 tis. Kč
    • •
  • MŠMT
Project

Platinum modified conductiong polymers as an alternative anode material for the low temperature fuel cells (GA104/02/0664)

. Platinum will be used as a catalyst. The main advantage of CP as a support is enhanced supposed that CP as a catalyst support enhances platinum utilization. This is because the platinum catalyst. Nowadays three fundamenta...

JE - Nejaderná energetika, spotřeba a užití energie

  • 2002 - 2004
    • •
  • 3 854 tis. Kč
    • •
  • 1 804 tis. Kč
    • •
  • GA ČR
Project

Structure, recognition and biochemistry of DNA modified by antitumor platinum drugs (IAA5004101)

activity of platinum-based compounds. The goal of these studies is to develop a systematic and complex theoretical background to the synthesis of novel platinum of cellular resistance to platinum drugs already used in the ...

EB - Genetika a molekulární biologie

  • 2001 - 2005
    • •
  • 4 464 tis. Kč
    • •
  • 2 629 tis. Kč
    • •
  • AV ČR
Project

The study of the thermodynamic stability of DNA modified by new anticancer platinum complexes (LZ1K03010)

The project is focused on studies of the mechanism underlying anticancer effects of platinum complexes. The activity of platinum compounds is generally associated with their ability to bind covalently to DNA. The effect of plati...

BO - Biofyzika

  • 2003 - 2004
    • •
  • 1 066 tis. Kč
    • •
  • 799 tis. Kč
    • •
  • MŠMT
  • 1 - 10 out of 128