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9 (0,049s) •

Project

Regulation of translation initiation during meiotic maturation of pig oocytes by protein factors associated with mRNA 3'-end (GA524/07/1087)

in the proposed project on the study of the role of polyadenylation and the factors associated with the mRNA 3'-end - cytoplasmic polyadenylation element binding protein (CPEB) and poly as a repressor and an activator of cytoplasmi...

ED - Fyziologie

  • 2007 - 2009
    • •
  • 2 335 tis. Kč
    • •
  • 2 335 tis. Kč
    • •
  • GA ČR
Project

Molecular mechanisms and evolution of RNA polyadenylation in euglenophyte plastids (GA21-19664S)

, we propose to illuminate a poorly understood phenomenon of RNA polyadenylation polyadenylation in different euglenophyte groups, characterize candidates for plastid proteins involved in poly-/deadenylation, and put the plastid RNA...

Genetics and heredity (medical genetics to be 3)

  • 2021 - 2023
    • •
  • 10 396 tis. Kč
    • •
  • 10 119 tis. Kč
    • •
  • GA ČR
Project

Role of the regulatory factors acting at 3’end of mRNA in correct progression of mammalian oocyte meiotic maturation. (GA15-22765S)

pattern of translation of specific transcripts and its regulation by polyadenylation...

EB - Genetika a molekulární biologie

  • 2015 - 2019
    • •
  • 6 781 tis. Kč
    • •
  • 6 781 tis. Kč
    • •
  • GA ČR
Project

The function of the TRAMP4 complex in the formation of 3'-ends of mRNAs in Saccharomyces cerevisiae (GA17-20388S)

) termination complex. The ncRNA transcripts are subsequently polyadenylated by the Trf4p/Air1p/Air2p/Mtr4p Polyadenylating (TRAMP4) complex, which is followed by 3'-end......

EB - Genetika a molekulární biologie

  • 2017 - 2021
    • •
  • 8 435 tis. Kč
    • •
  • 8 240 tis. Kč
    • •
  • GA ČR
Project

Modified nucleosides, nucleotides and oligonucleotides and their application in biomedicine (TA03010598)

Modified nucleosides, nucleotides and oligonucleotides are intensively used in medicine mainly as drugs or as components of diagnostic kits. The project is focused on the development of new tools for the detection of proliferating cells and on the sy...

EB - Genetika a molekulární biologie

  • 2013 - 2016
    • •
  • 15 280 tis. Kč
    • •
  • 9 880 tis. Kč
    • •
  • TA ČR
Project

Topography of nuclear architecture associated with the RNA synthesis,processing and transport. (GV304/96/K002)

steps (presence and number of introns, polyadenylation). Therefore, by means...

EB - Genetika a molekulární biologie

  • 1996 - 1998
    • •
  • 4 209 tis. Kč
    • •
  • 4 209 tis. Kč
    • •
  • GA ČR
Project

Structural studies of protein-RNA complexes involved in RNA quality control (GA204/08/1212)

-control pathways involves the exosome and the Trf4/Air2/Mtr4 polyadenylation (TRAMP...

EB - Genetika a molekulární biologie

  • 2008 - 2010
    • •
  • 6 990 tis. Kč
    • •
  • 2 490 tis. Kč
    • •
  • GA ČR
Project

Structural studies of protein-RNA complexes involved in RNA quality control (LA08008)

complexrecognizes and polyadenylates the aberrant RNAs, whereas the exosome is responsible...

CE - Biochemie

  • 2008 - 2010
    • •
  • 1 833 tis. Kč
    • •
  • 1 833 tis. Kč
    • •
  • MŠMT
Project

The molecular mechanisms of noncanonical 3' terminal RNA tailing and its role in the metabolism of coding and noncoding RNAs (GA20-19617S)

Eukaryotic RNAs undergo a wide variety of posttranscriptional modifications, such as base modifications or nontemplated 3'-end tailing. The 3' terminal RNA uridylation plays diverse roles in RNA metabolism acting in both, production of functional RNA...

Biochemistry and molecular biology

  • 2020 - 2022
    • •
  • 10 824 tis. Kč
    • •
  • 10 806 tis. Kč
    • •
  • GA ČR
  • 1 - 9 out of 9