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Projects

4 projects (0,151s) •

Project

Polydendrocyte function in regeneration after ischemic brain injury - the role of Wnt signaling pathway (GAP303/12/0855)

Polydendrocytes act as oligodendrocyte precursors both during and after neural of this project is to clarify the role of polydendrocytes in neurogenesis/gliogenesis after in polydendrocyte proliferation/differentiation duri...

FH - Neurologie, neurochirurgie, neurovědy

  • 2012 - 2015
    • •
  • 11 600 tis. Kč
    • •
  • 11 600 tis. Kč
    • •
  • GA ČR
Project

Age-related changes in brain diffusivity, extracellular matrix composition and glial physiology - impact on pathogenesis of ischemia (GA16-10214S)

Despite the fact that disorders resulting in the ischemic damage of the brain tissue, such as heart attack, stroke or embolia prevail in aged population, most of the experimental studies concerning pathogenesis of ischemia were done in young adult an...

FH - Neurologie, neurochirurgie, neurovědy

  • 2016 - 2019
    • •
  • 14 121 tis. Kč
    • •
  • 13 887 tis. Kč
    • •
  • GA ČR
Project

Principal signaling pathways regulating NG2 glia proliferation and differentiation following brain injuries (GA17-04034S)

In the adult brain NG2-glia represent an important cell type in relation to their proliferative capacity and ability to give rise to other types of neural cells following CNS injuries. Recent findings suggest that Sonic hedgehog (Shh) and Wnt ligands...

FH - Neurologie, neurochirurgie, neurovědy

  • 2017 - 2019
    • •
  • 12 507 tis. Kč
    • •
  • 11 937 tis. Kč
    • •
  • GA ČR
Project

Involvement of Wnt/β-catenin signaling in neurogenesis and gliogenesis following brain ischemic injury - analysis at the single cell level (GA21-24674S)

Ischemic injury of the brain is a pathological situation leading to death or permanent impairment of the cognitive, sensory, and motor functions. Recent studies indicate that the Wnt signaling pathway promotes cell proliferation and neurogenesis in t...

Neurosciences (including psychophysiology)

  • 2021 - 2023
    • •
  • 12 173 tis. Kč
    • •
  • 12 173 tis. Kč
    • •
  • GA ČR
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