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529 (0,103s)

Project

Thermodynamic and kinetic investigations of metal complexes of polydentate ligands for biomedical, analytical and industrial applications (LTC20044)

of medicinal interest. The ligands to be studied are macrocyclic polydentate ligands and ligands of industrial interest as polyamino-polyphosphonates. For these systems, both-ligand systems will be sought...

Inorganic and nuclear chemistry

  • 2020 - 2023
  • 4 890 tis. Kč
  • 4 890 tis. Kč
  • MŠMT
Project

Scandium complexes with polydentate ligands as potential radiopharmaceuticals (MEB021041)

the most basic ligands, in frame of the project, the most common polydentate aminocarboxylate ligands (linear ? EDTA, DTPA; macrocyclic ? NOTA, DOTA) will be investigated first. On basis of the results, analogous ligan...

CA - Anorganická chemie

  • 2010 - 2011
  • 106 tis. Kč
  • 106 tis. Kč
  • MŠMT
Project

Large polyaza macrocycles with coordinating pendant arms as ligands for large metal ions (GA25-17964S)

Chemistry of complexes of large metal ions with polydentate ligands have been overlooked until recently. The ions have become interested for nuclear medicine of studies dealing with design of new selective ligands. Thus, th...

Inorganic and nuclear chemistry

  • 2025 - 2027
  • 7 792 tis. Kč
  • 7 792 tis. Kč
  • GA ČR
Project

Catalysis by transition metal complexes with azine ligands (GA203/97/1157)

The project deals with a new type of polydentate ligands based on azines from the metal to the ligand backbone makes the ligands suitable for use in catalysis of those reactions in which hydride intermediates are i...

CA - Anorganická chemie

  • 1997 - 1999
  • 1 237 tis. Kč
  • 797 tis. Kč
  • GA ČR
Project

Electrochemically active calix[4]arenes and their use for preparation of new receptors and (bio)sensors (GA13-21704S)

, their abilities as polydentate ligands to form complexes; b) evaluation of their abilities...

CG - Elektrochemie

  • 2013 - 2016
  • 8 517 tis. Kč
  • 8 517 tis. Kč
  • GA ČR
Project

Selective Metal Complexation by Polytopic Lligands Towards Two-Metal Single-Molecule Probes for Biomedical Applications (GA19-17380S)

Polydentate ligands with high thermodynamic and/or kinetic selectivity. The research will be focused on relation between the structure of ligands and their selectivity for particular metal ion and stability of their complex...

Inorganic and nuclear chemistry

  • 2019 - 2021
  • 5 689 tis. Kč
  • 5 689 tis. Kč
  • GA ČR
Project

Novel electrochemically active thiacalix[4]arenes and their oxidized analogues as ligands and receptors (GA17-18108S)

The project is focused on "clasic" synthesis and electrosynthesis of novel electrochemically active calix[4]arenes as potential specific ligands and receptors for electroanalysis. In contrast to generally used calixarenes, electrochemically ...

CG - Elektrochemie

  • 2017 - 2019
  • 7 272 tis. Kč
  • 6 774 tis. Kč
  • GA ČR
Project

Multideprotonable, ambiphilic and hybrid ligands with appropriate shape and electron pool for formation of oligometallic complexes (GA17-10377S)

and ambiphilic ligands suitable for complexation of metal centres in generally low oxidation states. Suggested ligands are: amidinato/guanidinato ligands combined with N-heterocyclic carbenes, hybrid neutral ligands

CA - Anorganická chemie

  • 2017 - 2019
  • 7 464 tis. Kč
  • 7 050 tis. Kč
  • GA ČR
Project

Activation of the antitumor potential of lymphocytes through interaction with multivalent chitooligomer-based ligands (GA303/99/1382)

Within the frame of the project new glycosidic ligands will be prepared using a combination of chemical and enzymatic methods and the ligands will be tested of the ligand will be chitooligomers (containing beta-N-acetyl-glu...

EC - Imunologie

  • 1999 - 2001
  • 4 093 tis. Kč
  • 3 305 tis. Kč
  • GA ČR
Project

In-cell NMR spectroscopic studies of DNA–ligand interactions (8J18FR001)

i) Characterization of selectivity of macrocyclic ligands with respect of selectivity of macrocyclic ligands with respect to abasic DNA in complex intracellular Establishing the relationships between stability of DNA-ligand

Biochemical research methods

  • 2018 - 2019
  • 80 tis. Kč
  • 80 tis. Kč
  • MŠMT
  • 1 - 10 out of 529