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5 (0,051s)

Project

Use of HTG gene score in diagnosis of primary hypertriglyceridemias and assessment of the risk of gastrointestinal and cardiovascular complications (NV15-28876A)

Hypertriglyceridemia (HTG) contributes to non-alcoholic fatty liver disease and can increase atherogenicity of some lipoprotein subclasses, which, together with remnant lipoprotein particles, accelerate progression of atherosclerosis. Primary HTG is ...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2015 - 2018
  • 5 666 tis. Kč
  • 5 666 tis. Kč
  • MZ
Project

Effect genetic polymorphism lipogenic enzymes on the milk fat,composition of the fatty acids in milk in small rumimants (goat, sheep). (QJ1310107)

The main objective of the project is the creation of functional foods with a positive effect on human health. Furthermore, to reveal the influence of genetic variants of candidate genes for milk fat content, fatty acids in milk of small ruminants and...

EB - Genetika a molekulární biologie

  • 2013 - 2017
  • 13 598 tis. Kč
  • 12 149 tis. Kč
  • MZe
Project

The role of CD36 gene in pathogenesis of Alzheimer´s disease (NV18-04-00455)

The project is focused on the role of CD36 gene in the pathogenesis of cognitive disorders. It is based on our recent discovery of a significant association between CD36 gene and Alzheimer’s disease (AD). CD36 is involved in the removal of amyloid ß ...

Clinical neurology

  • 2018 - 2021
  • 11 992 tis. Kč
  • 11 992 tis. Kč
  • MZ
Project

Advanced biotechnological and behavioral approaches in dental caries research and prevention strategies (NV17-30439A)

Dental caries, a chronic multifactorial disease, is a major oral health problem worldwide. Its etiology involves a complex interplay of microbial, genetic, biochemical, social, physical environmental, and health-influencing behavioral factors. The pr...

FF - ORL, oftalmologie, stomatologie

  • 2017 - 2020
  • 12 342 tis. Kč
  • 11 699 tis. Kč
  • MZ
Project

The role of genetic variations in microRNA genes and in microRNA binding sites in colorectal cancer in relation to personalized therapy (NV15-26535A)

MicroRNAs (miRNAs), involved in post-transcriptional gene regulation, play relevant role in human cancer. Their aberrant function and/or expression often occur in colorectal cancer (CRC). Single nucleotide polymorphisms (SNPs) in miRNA genes and in 3...

EB - Genetika a molekulární biologie

  • 2015 - 2018
  • 6 414 tis. Kč
  • 6 414 tis. Kč
  • MZ
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