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5 (0,105s)

Project

Polyomaviruses Cellular responses to virion components (GA16-07977S)

The proposed project continues complex studies of molecular mechanisms of individual steps of infection by polyomaviruses (PyV). Unknown aspects of cellular responses to PyV components will be addressed: i) The hypothesis that the virus is s...

EE - Mikrobiologie, virologie

  • 2016 - 2020
  • 7 254 tis. Kč
  • 7 254 tis. Kč
  • GA ČR
Project

Delivery of Polyomavirus genomes into the cell nucleus and interactions of their structural proteins in host cells (GA13-26115S)

Polyomaviruses, small tumorogenic DNA viruses replicate in the cell nucleus. Although intensively studied, their interactions with host cells structures and mechanism of uncoating and delivery of viral genomes into the cell nucleus are still...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2013 - 2017
  • 7 539 tis. Kč
  • 7 539 tis. Kč
  • GA ČR
Project

Immune activation during polyoma BK virus infection after renal transplantation (NS9714)

To monitor the levels of BK viral DNA in the serum and urine in renal transplant recipients. To demonstrate, using molecular biology methods - analysis of expression of selected proinflammatory genes, that monitoring of the level of expression of sel...

FE - Ostatní obory vnitřního lékařství

  • 2008 - 2011
  • 4 360 tis. Kč
  • 4 360 tis. Kč
  • MZ
Project

New materials and technologies for diagnostics od polyomaviruses in immunodeficient patients. (TH01010548)

To prepare type-specific recombinant antigens of polyomavirus BK (BKV) and Merkel cell polyomavirus (MCV) in a form of virus ? like particles (VLP) and to elaborate technologies for their binding to solid surfaces. To use these tools for development ...

EE - Mikrobiologie, virologie

  • 2015 - 2017
  • 9 951 tis. Kč
  • 5 970 tis. Kč
  • TA ČR
Project

Functional Organisation of the Cell (LC545)

electrospray on ionic cyclotron. To identify the endocytotic pathway used by polyomaviruses...

EA - Morfologické obory a cytologie

  • 2005 - 2011
  • 131 084 tis. Kč
  • 96 589 tis. Kč
  • MŠMT
  • 1 - 5 out of 5