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22 950 (0,13s) •

Project

Preclinical development of new highly selective CK1 inhibitors for the treatment of selected oncological diseases (FW06010481)

diseases. The technology is currently in the preclinical phase of CLL research). Project activities: - Identification of lead candidates for advanced preclinical experiments - Initiation of GLP preclinical experiments - Co...

Pharmacology and pharmacy

  • 2023 - 2025
    • •
  • 20 862 tis. Kč
    • •
  • 14 275 tis. Kč
    • •
  • TA ČR
Project

The design and synthesis of novel ergopeptides with migraine-prophylactic properties (1P04OE159)

development of novel pharmaceutical preparations, migraine prevention, preclinical tests, novel ergopeptines...

FR - Farmakologie a lékárnická chemie

  • 2004 - 2006
    • •
  • 9 600 tis. Kč
    • •
  • 4 800 tis. Kč
    • •
  • MŠMT
Project

*Development of new technologies of preclinical testing of drugs. (FF-P2/025)

*The main aim of the project "Development of new technologies of pre-clinical testing of medical drugs" is development and introduction of new methods of long-term studies on higher mammal models such as dogs and monkeys.......

EG - Zoologie

  • 2003 - 2005
    • •
  • 11 297 tis. Kč
    • •
  • 2 199 tis. Kč
    • •
  • MPO
Project

The Developement of Radiopharmaceuticals and their Preclinic and Clinic Testing (IZ2706)

FR - Farmakologie a lékárnická chemie

  • 1995 - 1997
    • •
  • 3 843 tis. Kč
    • •
  • 2 793 tis. Kč
    • •
  • MZ
Project

The development of VUFB-19 363, the original antiastmatic with multiple mechanism of action. (FB-C3/09)

The project is dealing with the development of original antiastmatic VÚFB-19 363. The preclinical evaluation and clinical testing including the pilot study of the 2nd phase will be performed. The offering documentation as the additi...

CC - Organická chemie

  • 2000 - 2001
    • •
  • 9 637 tis. Kč
    • •
  • 4 664 tis. Kč
    • •
  • MPO
Project

DIANA panel for testing of selectivity of inhibitors of clinically relevant protein kinases and its application in the drug discovery market. Preclinical development of new inhibitors of CDK11 - key (FW03010138)

to pharma companies for preclinical and clinical development.The project has two main goals: 1) To develop DIANA-based assay panel for measuring potency and selectivity of inhibitors of CDK and other medicinally relevant p...

Pharmacology and pharmacy

  • 2021 - 2024
    • •
  • 46 407 tis. Kč
    • •
  • 33 138 tis. Kč
    • •
  • TA ČR
Project

Personalized Medicine – Diagnostics and Therapy (TN01000013)

chemistry, biological chemistry and preclinical development, biomarkers and DNA analysesCenter PerMedT is focused on applied research in diagnostics and therapy of rare and genetically determined diseases. The aim is to develo...

Pharmacology and pharmacy

  • 2019 - 2022
    • •
  • 223 884 tis. Kč
    • •
  • 178 916 tis. Kč
    • •
  • TA ČR
Project

Influencing of an oxidative stress, risk of impaired glucose tolerance, type 2 diabetes mellitus and preclinical atherosclerosis by treatment of hyperlipidemias. (NB7377)

Possibilities of favourable influencing of mechanisms leading to impaired glucose tolerance and DM 2 development will be observed in yet untreated patients with primary hypercholesterolemia and/or hypertriglyceridemia by using the statins or...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2003 - 2005
    • •
  • 2 633 tis. Kč
    • •
  • 2 545 tis. Kč
    • •
  • MZ
Project

New generation of the products for photodynamic therapy of cancer disease (LF14001)

Microcrystalisation of active compound and establishing the nanoparticle formulation. Preclinical trials of liposomal formulation and determination of photophysical properties of nanoparticles. Advanced studies of liposomal formulation and <...

FD - Onkologie a hematologie

  • 2014 - 2017
    • •
  • 23 000 tis. Kč
    • •
  • 11 500 tis. Kč
    • •
  • MŠMT
Project

Portable Small Animal Particle Irradiation and Imaging Unit (7D19002)

We will make a novel robotic platform for radiation research on preclinical animal models for various diseases. The platform will combine several imaging modalities with precision irradiation with photon and ion beams. This is a novel way wi...

Health-related biotechnology

  • 2019 - 2022
    • •
  • 12 426 tis. Kč
    • •
  • 6 214 tis. Kč
    • •
  • MŠMT
  • 1 - 10 out of 22 950