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Differences in regulation of cell cycle checkpoints between zygote and 2-cell embryo (GA20-27742S)
During mouse preimplantation development G1 is long and G2 short in the zygote, whereas G1 is extremely short and G2 very long in the 2-cell embryo. In somatic cells but preimplantation development is normal, likely driven...
Cell biology
- 2020 - 2023 •
- 7 114 tis. Kč •
- 7 114 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2020 - 30. 6. 2023
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Examination of DNA instability in gametes, embryos and somatic cells following oncological therapy for improvement of reproductive success in treated patients. (NT13770)
in chromosomal aberrations of somatic cells, gametes, embryos, disturbances of preimplantation and embryonal development associated with dysfertility. Utilised methods therapy in IVF, risks of gamete / embryo / gonad cryop...
FD - Onkologie a hematologie
- 2012 - 2015 •
- 9 783 tis. Kč •
- 9 783 tis. Kč •
- MZ
Řešení projektu: 1. 4. 2012 - 31. 12. 2015
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Maternal protein degradation and its impact on the development quality of mammalian preimplantation embryo (GA23-05108S)
). Further, we will determine the expression profiles in bovine embryos of proteins...
Developmental biology
- 2023 - 2025 •
- 8 123 tis. Kč •
- 8 123 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2023 - 31. 12. 2025
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Embryonic gene expression and posttranscriptional gene silencing during bovine preimplantation development (GA523/09/1035)
, preimplantation bovines embryo is much more humanlike and alike to other mammals. There have embryo depending on different cultivation conditions. Especially when microarrays of silenced andcontrol embryos on mic...
EB - Genetika a molekulární biologie
- 2009 - 2011 •
- 3 342 tis. Kč •
- 3 342 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2009 - 31. 12. 2011
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
The Role of Skp1-Cullin1-F-box Complex in Protein Ubiquitination and Degradation during Bovine Preimplantation Development (GP13-24730P)
At the beginning of preimplantation development all the mRNAs and proteins are of maternal origin. The development starts to be controlled by the embryo own only after of the most important processes of preimplantation deve...
EB - Genetika a molekulární biologie
- 2013 - 2018 •
- 2 709 tis. Kč •
- 2 709 tis. Kč •
- GA ČR
Řešení projektu: 1. 2. 2013 - 5. 12. 2018
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
From meiosis to mitosis - is starting a new life under in vitro conditions equivalent to that in vivo? (GA22-27301S)
as for preimplantation embryos to produce new proteins in the spatial and temporal patterns that drive gamete and embryo development. With the increasing use of assisted the physiology of the “in vitro” produced embryo...
Reproductive biology (medical aspects to be 3)
- 2022 - 2024 •
- 13 443 tis. Kč •
- 12 855 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2022 - 31. 12. 2024
Uznané náklady
Podpora ze státního rozpočtu (96%)
Poskytovatel: Grantová agentura České republiky
Non-coding RNAs matters role in mammalian oocyte and embryo (GA18-19395S)
foundation to embryo development. Importantly, fully-grown oocyte becomes development. In addition to protein-coding messenger RNAs, oocytes and embryos produce for oocyte and early embryo biology and pathophysiology is st...
Reproductive biology (medical aspects to be 3)
- 2018 - 2021 •
- 6 033 tis. Kč •
- 5 640 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2018 - 31. 12. 2021
Uznané náklady
Podpora ze státního rozpočtu (93%)
Poskytovatel: Grantová agentura České republiky
Improvement of the prevention of the most common chromosomal abberations and cystic fibrosis in the preimplantation phase of development. (NR7962)
The aim is improvement of prevetion of the most common chromosomal aberrations and cystic fibrosis in the preimplantation phase of development for the improvement of IVF success rates and prevention of these severe errors of prenatal and pos...
EB - Genetika a molekulární biologie
- 2004 - 2006 •
- 999 tis. Kč •
- 998 tis. Kč •
- MZ
Řešení projektu: 1. 1. 2004 - 1. 1. 2006
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
In vitro oocyte culture vs in vivo oocyte development - is their physiology really comparable? (GA19-13491S)
Regulated mRNA translation is vital for germ cells, as well as for preimplantation embryos to produce new proteins in the spatial and temporal patterns that drive gamete and embryo development. With the increasing use of as...
Reproductive biology (medical aspects to be 3)
- 2019 - 2022 •
- 8 748 tis. Kč •
- 8 235 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2019 - 30. 6. 2022
Uznané náklady
Podpora ze státního rozpočtu (94%)
Poskytovatel: Grantová agentura České republiky
Cellular and molecular basis of oogenesis fertilization and embryonic development in mammals (GV524/96/K162)
preimplantation development of bovine embryos. The precise comparison with zygotic gene growingoocytes in embryo transfer program. Moreover, the role of cell surface proteins. The mesoderm specification in the mouse em...
EB - Genetika a molekulární biologie
- 1996 - 2001 •
- 33 038 tis. Kč •
- 25 187 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 1996 - 1. 1. 2001
Uznané náklady
Podpora ze státního rozpočtu (76%)
Poskytovatel: Grantová agentura České republiky
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