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7 (0,045s) •

Project

Humulus Lupulus L. - source of substances with antimicrobial effect (GA14-10233S)

, especially prenylflavonoids. For this reason, a profiling method for highly detailed...

FR - Farmakologie a lékárnická chemie

  • 2014 - 2016
    • •
  • 7 641 tis. Kč
    • •
  • 7 641 tis. Kč
    • •
  • GA ČR
Project

Mechanisms of propagation and crossprotection among viroids infecting hop and apple and their influence on regulation of metabolite pathways of medicinal prenylflavonoids and lupulin. (LH14255)

The main purpose of the project is to analyze combinatorial infections of hop and fruit trees caused by group of viroids from family Pospiviroidae; the aim is to characterize their concurrent propagation, compatibility, variation and possible synergi...

EB - Genetika a molekulární biologie

  • 2014 - 2016
    • •
  • 1 454 tis. Kč
    • •
  • 1 454 tis. Kč
    • •
  • MŠMT
Project

Research of bioactive substances from hops body scrap and their utilization in food supplement products. (FT-TA2/014)

Research of bioactive substances from hops body scrap and their utilization in food supplement products. The rest after extraction has not been bythat time fully exploited, although it is a rich source of polyphenols, especially prenylated flavonoids...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2005 - 2008
    • •
  • 26 501 tis. Kč
    • •
  • 14 650 tis. Kč
    • •
  • MPO
Project

Aspects of proteomics of chalcone synthases and chalcone synthase-like proteins in hop important for lupulin biosynthesis (GP521/06/P323)

Hop (Humulus lupulus L.) is a source of +-acids and aromatic compounds for beer industry. Nowadays many compounds isolated from hop are intensively investigated, especially compounds of the group of prenylated flavonoids, particularly xanthohumol for...

EB - Genetika a molekulární biologie

  • 2006 - 2008
    • •
  • 1 200 tis. Kč
    • •
  • 1 200 tis. Kč
    • •
  • GA ČR
Project

Molecular analysis of lupulin glands initiation in hop with regard to transcription factors identified by genome-wide transcriptome profiling. (GA19-19629S)

Hop is cultivated for female cones containing in their glandular trichomes secondary metabolites, such as bitter acids or prenylflavonoids valuable for brewing industry and for pharmaceutical and medicinal applications. Amount and compositi...

Plant sciences, botany

  • 2019 - 2021
    • •
  • 10 737 tis. Kč
    • •
  • 10 737 tis. Kč
    • •
  • GA ČR
Project

Molecular analysis of transcription factors of hop (H. lupulus L.) in relation to lupulin biosynthesis (GA521/08/0740)

Previously we characterized an oligofamily chalconsynthase genes chs_H1 from hop, expressed in glandular tissue and  involved in production of "medicinal" prenylflavonoids and bitter acids important in brewing idustry. We also initialized an...

EB - Genetika a molekulární biologie

  • 2008 - 2011
    • •
  • 4 453 tis. Kč
    • •
  • 4 453 tis. Kč
    • •
  • GA ČR
Project

Combinatorial regulation and network of transcription factors involved in the biosynthesis of medicinal prenylflavonoids in hop (Humulus lupulus L.). (GA13-03037S)

Hop is source of bitter acids and medicinal prenylchalcones, including xanthohumol. During last years we have characterized lupulin-specific chalcone synthase chs_H1 and transcription factors from Myb, bHLH and WDR families that act in a transcriptio...

EB - Genetika a molekulární biologie

  • 2013 - 2017
    • •
  • 14 323 tis. Kč
    • •
  • 14 323 tis. Kč
    • •
  • GA ČR
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