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4 927 (0,126s) •

Project

Induction of chimerism by transplantation of germ stem cells in critically endangered sturgeons as a tool of their conservation (GA13-26952S)

sturgeon germ stem cells (GSCs) such as primordial germ cells or subsequently oogonial/spermatogonial stem cells and ability of their cryopreservation and xenogeneic transplantation. The main goa...

EB - Genetika a molekulární biologie

  • 2013 - 2017
    • •
  • 10 730 tis. Kč
    • •
  • 10 730 tis. Kč
    • •
  • GA ČR
Project

Biotechnological approaches in reproduction of freshwater fish (LH13246)

) using manipulation with germ cells (PGCs/spermatogonia/oogonia). We will transplant isolated germ celss into closely related species characteristic by small body size on cryopreserved germ cells for reco...

GL - Rybářství

  • 2013 - 2014
    • •
  • 1 284 tis. Kč
    • •
  • 1 284 tis. Kč
    • •
  • MŠMT
Project

Identification of epigenetic biomarkers of male germ cell disorders linked to adverse environmental factors (GAP503/12/1834)

and the transfer of epigenetic defects in the gonads and germ cells in future generations posttranslational modification. Analysis of changes in the level of molecules and cells will be carried out on spermatozoa and sper...

DN - Vliv životního prostředí na zdraví

  • 2012 - 2015
    • •
  • 10 588 tis. Kč
    • •
  • 10 588 tis. Kč
    • •
  • GA ČR
Project

Gene targeting in chicken and the resistance to newly emerging retroviruses (GA15-23993S)

genome editing technique will be applied in chicken primordial germ cells into the cells of susceptible species (chicken and turkey) and deletions or substitutions and other galliforms). We suggest derivation of p...

EB - Genetika a molekulární biologie

  • 2015 - 2019
    • •
  • 7 303 tis. Kč
    • •
  • 7 010 tis. Kč
    • •
  • GA ČR
Project

Genetic sources of antiviral resistance in the domestic chicken (QL24010315)

and primordial germ cell transplantation techniques in poultry will also be developed...

Husbandry

  • 2024 - 2028
    • •
  • 38 737 tis. Kč
    • •
  • 28 295 tis. Kč
    • •
  • MZe
Project

Creation of isogenic lines and in vitro conservation of genetic resources of common carp using transplantation of germ cells (QK1910428)

aim of this project is to set-up isolation and cryoconservation of germ cells, sterilization of common carp and goldfish, transplantation of germ cells of carp into bodyThe aim of the project is to implement alter...

Fishery

  • 2019 - 2023
    • •
  • 11 866 tis. Kč
    • •
  • 11 866 tis. Kč
    • •
  • MZe
Project

Mature fast, die young, but what about germ cells? Germline development and aging in the turquoise killifish - naturally short-lived vertebrate. (GN22-01781O)

is known on how germ stem cells age in non-mammalian vertebrates despite their significance. Germ stem cells are precursors of the gametes, which makes them irreplicable fish model – the turquoise killifish. The c...

Fishery

  • 2022 - 2025
    • •
  • 4 561 tis. Kč
    • •
  • 4 561 tis. Kč
    • •
  • GA ČR
Project

Sturgeon as a unique model for evolutionary transition from holoblastic to meroblastic cleavage pattern, and for endoderm development in vertebrates (GA20-23836S)

The first cell divisions after egg fertilization are crucial steps of newly formed organism. Unfortunately understanding about early cleavages and their impact cells contain yolk platelets, which are digested intracellularly. Sturge...

Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology

  • 2020 - 2022
    • •
  • 8 220 tis. Kč
    • •
  • 8 220 tis. Kč
    • •
  • GA ČR
Project

Chicken pluripotent cells as source for production of transgenic poultry (ME 288)

The object of this project is to isolate Czech and Chinese chicken pluripotent cells (blastodermal,primordial gonocytes) for production of transgenic birds. These cells will be either immediately, or after incubation transf...

GI - Šlechtění a plemenářství hospodářských zvířat

  • 1998 - 2000
    • •
  • 1 980 tis. Kč
    • •
  • 960 tis. Kč
    • •
  • MŠMT
Project

Syncytins as markers of germ line tumors (NT14601)

in tumors of the male germ line, particularly seminomas, mixed germinal carcinomas with the representation of of multinuclear giant cells. Expression of syncytins will be assessed methylation of syncytin promoters and LTRs in afore...

FD - Onkologie a hematologie

  • 2013 - 2015
    • •
  • 5 340 tis. Kč
    • •
  • 5 340 tis. Kč
    • •
  • MZ
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