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5 (0,082s)

Project

Primary progressive aphasia – clinical, MRI and structural correlations. A prospective multicenter study (NV18-04-00346)

Primary progressive aphasias (PPA) are neurodegenerative disorders with an initial isolated language impairment progressing into dementia. Data about individual progression of PPA patients are sparse, as most large studies are retrospective. The proj...

Clinical neurology

  • 2018 - 2022
  • 14 247 tis. Kč
  • 13 667 tis. Kč
  • MZ
Project

Diagnostic markers and pathophysiological mechanisms of atypical parkinsonian syndromes (NT12288)

The project is designed to study clinical and paraclinical markers with a high positive predictive diagnostic value for atypical parkinsonian syndromes and to investigate the contribution of the inhibitory GABA-ergic system in the disorders of gait, ...

FH - Neurologie, neurochirurgie, neurovědy

  • 2011 - 2015
  • 8 122 tis. Kč
  • 8 122 tis. Kč
  • MZ
Project

A NEUROPALLIATIVE REHABILITATION APPROACH TO PRESERVE THE QUALITY OF LIFE IN PATIENTS WITH AN ADVANCED STAGE OF SELECTED NEUROLOGICAL DISEASES (NV17-29447A)

The main aim of the project is to create and verify a concept of neuropalliative and rehabilitative care for patients with selected neurological diseases in an advanced stage of the disease. Further, to evaluate bio-psychosocial and spiritual needs o...

FQ - Veřejné zdravotnictví, sociální lékařství

  • 2017 - 2020
  • 5 960 tis. Kč
  • 5 113 tis. Kč
  • MZ
Project

Genetic factors of progressive hearing loss of cochlear implantation candidates a potential for stratification of their therapy (NV19-06-00189)

Hearing impairment (HI) affects 15% to 50% of population, depending on age, up to 75% having genetic origin. Yet, no studies have been carried out on genetic causes of progressive post-lingual HI (PPHI) in larger cohorts. In this study, we use the ne...

Human genetics

  • 2019 - 2022
  • 10 064 tis. Kč
  • 10 064 tis. Kč
  • MZ
Project

Analysis of the genetic etiology of progressive hearing loss using WGS and innovative bioinformatics approaches (NW24J-06-00119)

Genetic causes of progressive or postlingual hearing loss (PHL) has been long underestimated worldwide, in favour of environmental causes. Our pilot study have proven importance of genetic causes of PHL (46.8 % of PHL had genetic background). During ...

Human genetics

  • 2024 - 2027
  • 6 961 tis. Kč
  • 6 961 tis. Kč
  • MZ
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