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1 167 (0,117s) •

Project

The possible role of stable analogs of prolactin-releasing peptide in experimental models of obesity and hypertension (GA15-08679S)

effect. Prolactin-releasing peptide (PrPR) is a new anorexigenic neuropeptide; bothAnorexigenic neuropeptides are potential anti-obesitics but their peptide peptides involved in food intake regulation wil...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2015 - 2017
    • •
  • 9 867 tis. Kč
    • •
  • 9 867 tis. Kč
    • •
  • GA ČR
Project

Obesity, diabetes and neurodegeneration crosstalk New therapeutic potential of prolactin-releasing peptide analogs (GA20-00546S)

analogs of anorexigenic prolactin-releasing peptide as a complex therapy...

Physiology (including cytology)

  • 2020 - 2022
    • •
  • 14 571 tis. Kč
    • •
  • 13 281 tis. Kč
    • •
  • GA ČR
Project

Lipidized analogs of prolactin-releasing peptide as potential agents for obesity therapy search for mechanism of action (GA18-10591S)

Anorexigenic neuropeptides such as prolactin-releasing peptide (PrRP) are potential anti-obesitics but they are unable to exert their exclusively central effect after peripheral administration. In our recent studies, we dem...

Endocrinology and metabolism (including diabetes, hormones)

  • 2018 - 2020
    • •
  • 10 641 tis. Kč
    • •
  • 9 249 tis. Kč
    • •
  • GA ČR
Project

New pharmacological interventions influencing energy homeostasis and development of insulin resistance/ type 2 diabetes mellitus (GAP303/10/1368)

intake such as prolactin-releasing peptide (PrRP) and cocaine- and amphetamine-regulated transcript (CART) peptide represent new possibilities in development of future for minimal biologically active structures of...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2010 - 2013
    • •
  • 9 715 tis. Kč
    • •
  • 9 715 tis. Kč
    • •
  • GA ČR
Project

Neuroprotective effects of novel analogs of anorexigenic prolactin-releasing peptide (PrRP) in mouse models of neurodegeneration and obesity (GA16-00918S)

anorexigenic peripherally administered and centrally acting analogs of prolactin-releasing peptide (PrRP) have similar beneficial effect on the mentioned neurodegenerative-like peptide-1 agonists showing anorexige...

FH - Neurologie, neurochirurgie, neurovědy

  • 2016 - 2018
    • •
  • 8 583 tis. Kč
    • •
  • 7 815 tis. Kč
    • •
  • GA ČR
Project

Neuropeptide FF-2 receptor as a potential anti-obesity target Impact of new analogs of RF-amide peptides (GA21-03691S)

and energy expenditure. This project deals with two RF-amide peptides, prolactin-releasing peptide (PrRP) and neuropeptide FF (NPFF), and their receptors GPR10 and NPFF administration. In this project we would lik...

Physiology (including cytology)

  • 2021 - 2023
    • •
  • 11 297 tis. Kč
    • •
  • 10 676 tis. Kč
    • •
  • GA ČR
Project

The dopamine and prolactin role during tumor progression and immunomodulatory effect of dopaminergic ergot alkaloids. (GA310/98/0347)

, in correlation to the important multifunctional hormone, prolactin ( PRL ), and its with their antagonistic counterparts. These stidies wil be orientated to the modulationof PRL release and lymphocytes. The project involves molecu...

FD - Onkologie a hematologie

  • 1998 - 2000
    • •
  • 2 607 tis. Kč
    • •
  • 2 489 tis. Kč
    • •
  • GA ČR
Project

'Thyrotropin Releasing Hormone' Related Peptides ('TRH-Like' Peptides) (GA311/93/0994)

ED - Fyziologie

  • 1993 - 1995
    • •
  • 390 tis. Kč
    • •
  • 780 tis. Kč
    • •
  • GA ČR
Project

Thyrotropin releasing hormone - TRH-like peptides (IZ849)

ED - Fyziologie

  • 1992 - 1994
    • •
  • 0 tis. Kč
    • •
  • 0 tis. Kč
    • •
  • MZ
Project

Prolactin and rheumatoid arthritis (NR9292)

I: Prolactin participates in the etiopathogenesis of autoimmune disorders. II: Prolactin is producted by inflammation-activated peripheral blood cells. III: Several works are available which evidence its presence in the synovial flu...

FE - Ostatní obory vnitřního lékařství

  • 2007 - 2009
    • •
  • 3 616 tis. Kč
    • •
  • 3 459 tis. Kč
    • •
  • MZ
  • 1 - 10 out of 1 167