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17 (0,142s) •

Project

Application of proline rich sequences in biologically active peptides (GA203/00/0955)

We suggest to study peptide sequences rich of proline and of its derivative of glycine which exhibit this activity at N-terminal part of the molecule, proline or even cummulated presence of the proline (and of its above der...

CC - Organická chemie

  • 2000 - 2002
    • •
  • 2 082 tis. Kč
    • •
  • 1 570 tis. Kč
    • •
  • GA ČR
Project

Effects of drought and heat stress on polyamine metabolism in wild type and transgenic tobacco plants. (OC08013)

The aim of this project is to elucidate the role of proline and polyamines, metabolites with the crucial protective functions, in the stress response of tobacco plants to high temperature and drought. Characterization of defense response in ...

ED - Fyziologie

  • 2008 - 2011
    • •
  • 2 527 tis. Kč
    • •
  • 1 707 tis. Kč
    • •
  • MŠMT
Project

Development of Novel Ribosome-Targeting Antibiotics (8F19006)

The overall objective is to identify, characterize and optimize molecules as novel lead compounds for the development of novel antimicrobial agents targeting translation.......

Microbiology

  • 2019 - 2022
    • •
  • 5 836 tis. Kč
    • •
  • 5 836 tis. Kč
    • •
  • MŠMT
Project

Studies of mutant mice with a lack of anchoring protein cholinesterase, PRIMA (MEB0810127)

To find out which receptor systems are involved in the adaptive mechanisms responsible for the survival of mice with zero activity of acetylcholinestrasis. The outcomes of research will broaden our knowledge of neurodegenerative diseases and their tr...

ED - Fyziologie

  • 2010 - 2011
    • •
  • 60 tis. Kč
    • •
  • 60 tis. Kč
    • •
  • MŠMT
Project

Proteomic phenotyping of wheat and barley under abiotic stresses (LD15167)

, proline, abscisic acid) will be performed to obtain the detailed information about...

GE - Šlechtění rostlin

  • 2015 - 2017
    • •
  • 1 688 tis. Kč
    • •
  • 1 688 tis. Kč
    • •
  • MŠMT
Project

Immobilized Enantioselective Catalysts (GA14-00925S)

of proline, quinine, cyclohexan1,2-diamine,1,2-diphenylethan-1,2-diamine), which...

CI - Průmyslová chemie a chemické inženýrství

  • 2014 - 2016
    • •
  • 4 997 tis. Kč
    • •
  • 4 997 tis. Kč
    • •
  • GA ČR
Project

Metabolic adaptations of cancer cells The role of amino acid metabolism in cancer resistance and treatment (GA25-18052S)

Abstract The application aims to delineate the role of amino acids, in particular proline and aspartate in the context of cancer resistance and treatment. The obtained results will provide novel targets and molecular mechanisms that are re...

Biochemistry and molecular biology

  • 2025 - 2027
    • •
  • 9 804 tis. Kč
    • •
  • 9 804 tis. Kč
    • •
  • GA ČR
Project

SNW Proteins in signal transduction (GA204/98/0406)

The SNW proteins are being found in diverse types of eukaryotic cells (including yeast, plant, Dictyostelium, worm, insect and man) and contain highly conserved regions implicated in protein-protein interactions (SH2-like, proline rich, amfi...

EB - Genetika a molekulární biologie

  • 1998 - 2000
    • •
  • 3 586 tis. Kč
    • •
  • 2 686 tis. Kč
    • •
  • GA ČR
Project

Response of plants to abiotic stress by selected heavy metals (GA525/02/0301)

and proline contents will also be followed. Biosynthesis of metallothioneins (MTs...

ED - Fyziologie

  • 2002 - 2004
    • •
  • 3 927 tis. Kč
    • •
  • 1 893 tis. Kč
    • •
  • GA ČR
Project

Genes determining critical steps in designing the producers of hybrid lincosamide antibiotics (IAA500200810)

The project aims to resolve the following findings: 1. High variability of homologous genes of proline building unit synthesis was observed between lincomycin and anthramycin antibiotic producers as well as inside the anthramycin group. To e...

EE - Mikrobiologie, virologie

  • 2008 - 2011
    • •
  • 4 465 tis. Kč
    • •
  • 4 465 tis. Kč
    • •
  • AV ČR
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