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3 529 (0,114s) •

Project

Vaccines for induction of mucosal and systemic immunity (IBS5020311)

pathogens. Towards this goal we will use a preclinically established antigen vector targeting antigen presenting cells, the adenylate cyclase toxoid (ACT), that can mediate intestines, it is expected that it will allow sustained de...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2003 - 2005
    • •
  • 6 070 tis. Kč
    • •
  • 5 365 tis. Kč
    • •
  • AV ČR
Project

Development of a new vaccine against Staphylococcus aureus (EI22_002/0000585)

. The prepared vaccine does not use either cell antigens or cell wall proteins or a live attenuated microorganism, i.e. the usually preferred antigenic bases present in other vaccines developed against staphylococci, as antigeni...

Pharmacology and pharmacy

  • 2023 - 2026
    • •
  • 34 033 tis. Kč
    • •
  • 0 tis. Kč
    • •
  • MPO
Project

Synthesis and characterization of synthetic antigens (GA203/03/1362)

usedpreviously with succes as antigenic carrier in the preparation of antibodies agains for the subsequent studies of coupling to antigens, immunological response andphysico-chemical properties. We will use differential protect...

CC - Organická chemie

  • 2003 - 2005
    • •
  • 2 148 tis. Kč
    • •
  • 1 218 tis. Kč
    • •
  • GA ČR
Project

Synthetic multiepitopic vaccine agains boreliosis intended for veterinary applications (TA01011165)

vaccines with recombinant antigens and testing their efficacy, safety and protectivityDevelopment of technology for production, purification and stabilisation of subtypes of recombinant chimeric multiepitopic antigens OspC...

FP - Ostatní lékařské obory

  • 2011 - 2014
    • •
  • 30 472 tis. Kč
    • •
  • 23 463 tis. Kč
    • •
  • TA ČR
Project

CMV specific mRNA vaccine for ex vivo stimulation of T cells in patiens after hematopoietic stem cell transplantation (NT13898)

Here, we propose to prepare mRNA vaccine against a number of candidate immunogenic CMV proteins. The vaccine will include antigen presenting cells electroporated mRNA coding for viral protective antigens and immunostimulato...

FD - Onkologie a hematologie

  • 2012 - 2015
    • •
  • 9 717 tis. Kč
    • •
  • 9 717 tis. Kč
    • •
  • MZ
Project

Comparison of a Recombinant hsp90 Protein Vaccine and DNA Vaccine Protectivity in Mouse Vaginal and Systemic Candidiasis Model (NI7538)

Candida albicans hsp90 protein is considered as an immunodominant potentially protective antigen suitable to induce specific T cells and specific antibodies protective against mucosal and disseminated candidiasis. Induction...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2003 - 2005
    • •
  • 2 141 tis. Kč
    • •
  • 2 101 tis. Kč
    • •
  • MZ
Project

*Industrial research of the most complex (11 antigens per 1 vaccination dose) vaccine Biocan Max DHPPi+L5CR protecting dogs worldwide against serious infectious diseases which can be used by vets (FR-TI1/161)

*Research and development of an original vaccine for immunoprophylaxis of canine infectious diseases. New composition of a vaccine corresponding to the world situation in canine infection occurence. By protection of dogs in ensured also ...

GJ - Choroby a škůdci zvířat, veterinární medicina

  • 2009 - 2012
    • •
  • 53 175 tis. Kč
    • •
  • 24 000 tis. Kč
    • •
  • MPO
Project

Strategy of oral immunization significance for systemic and mucosal immunity and use for prevention and therapy (VS96149)

on induction of protective immunity or oral tolerance will be tested. Bacillus firmus has strong immunomodulatory activities and will be used as adjuvant and antigen carrier epitopes will be exploited in the study of antigen

EA - Morfologické obory a cytologie

  • 1996 - 2000
    • •
  • 16 931 tis. Kč
    • •
  • 14 895 tis. Kč
    • •
  • MŠMT
Project

Growing field Advancing understanding of fish mucosal immunology through molecular farming (GA24-13026S)

, resulting in the low protective efficacy of oral vaccines. Combining the complementary antigens produced in plants to elucidate all major stages of the immune response, including antigen uptake, presentation, and activati...

Anatomy and morphology (plant science to be 1.6)

  • 2024 - 2026
    • •
  • 10 883 tis. Kč
    • •
  • 10 883 tis. Kč
    • •
  • GA ČR
Project

Innate-glycan-mediated and specific IgA-dependent protection in bacterial intestinal infection of experimental animals (GA17-11275S)

Gut mucosa is colonized by diverse commensal bacteria coated with IgA antibodies. In addition to the antigen-specific interaction, the binding of IgA to the bacteria is also mediated by glycans linked to the heavy chain (H) and secretory ant...

EC - Imunologie

  • 2017 - 2021
    • •
  • 9 518 tis. Kč
    • •
  • 9 352 tis. Kč
    • •
  • GA ČR
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