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106 (0,085s) •

Project

High precision quantification of rodent and human pancreatic islets for transplantation (NU22-01-00141)

islets and pseudo-islets in vitro. We will test the proposed methods in vitro pseudo-islets in vitro and in clinical studies.Clinical outcome of pancreatic islet transplantation depends on the nu...

Transplantation

  • 2022 - 2025
    • •
  • 11 544 tis. Kč
    • •
  • 11 544 tis. Kč
    • •
  • MZ
Project

Research and development of complex technology of special tungsten pseudo alloys based on powder metallurgy (EG15_019/0004339)

Research and development of complex technology of special tungsten pseudo alloys based on powder metallurgy...

JK - Koroze a povrchové úpravy materiálu

  • 2015 - 2020
    • •
  • 36 642 tis. Kč
    • •
  • 13 384 tis. Kč
    • •
  • MPO
Project

In vitro and in vivo function of isolated animal and human pancreatic iskets and the possibility of its modification in allogenic transplantation (ND6362)

pancreatic islet isolation and the study of potential induction of immunologic islet tolerance with bone marrow co-transplantation. Islet function will be tested a time-limited immunosuppression. Islets from the s...

FJ - Chirurgie včetně transplantologie

  • 2000 - 2002
    • •
  • 3 029 tis. Kč
    • •
  • 2 914 tis. Kč
    • •
  • MZ
Project

Optimalization of the culture conditions of the isolated Langerhans islets for transplantation (NT13099)

We will test new methods of protection and cultivation of isolated pancreatic islets designed for transplant therapy of diabetes using the following modifications inhibitors and the use of mesenchymal stem cells conditioned medium for is...

FJ - Chirurgie včetně transplantologie

  • 2012 - 2015
    • •
  • 7 019 tis. Kč
    • •
  • 6 936 tis. Kč
    • •
  • MZ
Project

Automatic analysis of microscopy images of Langerhans islets (GA14-10440S)

Transplantation of isolated islets of Langerhans is an experimental treatment evaluation of the quantity and shape of the isolated islets, in order to assess consuming and inaccurate because of unsubstantiated assumptions of the

JD - Využití počítačů, robotika a její aplikace

  • 2014 - 2018
    • •
  • 3 865 tis. Kč
    • •
  • 3 865 tis. Kč
    • •
  • GA ČR
Project

Butyrylcholinesterase reactivators for preparation of pseudo-catalytic scavengers applicable for organophosphorus intoxications (GA18-01734S)

Organophosphorus compounds are produced as chemical warfare agents or used as insecticides and cause life endangering intoxications. The concept of pseudo-catalytic with specific sorbent. However for pseudo-catalytic concept, there ...

Pharmacology and pharmacy

  • 2018 - 2020
    • •
  • 10 288 tis. Kč
    • •
  • 9 283 tis. Kč
    • •
  • GA ČR
Project

Novel method of pancreatic islet transplantation into the omentum (NV17-29009A)

hypoglycemia unawareness in which transplantation of pancreatic islets would be indicated according to current criteria. In contrast to present routine the islet preparation gel matrix for islet adherence and to compare t...

FJ - Chirurgie včetně transplantologie

  • 2017 - 2021
    • •
  • 13 100 tis. Kč
    • •
  • 13 013 tis. Kč
    • •
  • MZ
Project

Epigenetic intervention as a tool improving the outcomes of pancreatic islet transplantation (GA14-03305S)

The transplantation of pancreatic islets is a clinically relevant therapeutic by an insufficient sources and a substantial islet loss during isolation, preservation) as a promising tool for better islet preservation during ...

FJ - Chirurgie včetně transplantologie

  • 2014 - 2018
    • •
  • 5 475 tis. Kč
    • •
  • 5 475 tis. Kč
    • •
  • GA ČR
Project

The use of pancreatic islet extracellular matrix for propagation and controlled differentiation of insulin producing cells (GA19-07661S)

Pancreatic islet transplantation into the liver represents an established plan to use the native extracellular pancreatic or single islet matrix (ECM) as the skeletons for seeding with 1) native pancreatic islets and 2) bio...

Endocrinology and metabolism (including diabetes, hormones)

  • 2019 - 2022
    • •
  • 9 458 tis. Kč
    • •
  • 9 458 tis. Kč
    • •
  • GA ČR
Project

Pancreatic islets transplantation into the subcutaneous pouch - a preclinical study (NV16-28249A)

Transplantation of isolated pancreatic islets is limited by low efficiency of islet isolation from cadaveric pancreases as well as by an insufficient islet the short-term survival of islet cells and subsequent long...

FJ - Chirurgie včetně transplantologie

  • 2016 - 2020
    • •
  • 7 610 tis. Kč
    • •
  • 7 550 tis. Kč
    • •
  • MZ
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