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39 (0,074s) •

Project

Pseudomonas aeruginosa in patients with cystic fibrosis an impact of early PCR-indicated therapy, identification of routes of the infection spread (NR7974)

The effective treatment of infection with Pseudomonas aeruginosa in patients with cystic fibrosis requires early pathogen detection. Highly sensitive detection of the P.aeruginosa using nested PCR will be the indication to start an ...

FG - Pediatrie

  • 2004 - 2006
    • •
  • 3 282 tis. Kč
    • •
  • 2 931 tis. Kč
    • •
  • MZ
Project

The status and nature of resistance to antimicrobial agents in Pseudomonas aeruginosa isolates from invasive infections. (NR9428)

Detailed genetic population analysis with the aim to obtain comprehensive information on the status, nature and modes of spread of resistance to antimicrobial agents in clinically most relevant P. aeruginosa strains in the Czech Republic. A ...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2007 - 2009
    • •
  • 2 237 tis. Kč
    • •
  • 2 209 tis. Kč
    • •
  • MZ
Project

Profylactic vaccination with vaccina psaeva in prostatectomized patients. (IZ2146)

9F - 9

  • 1994 - 1995
    • •
  • 30 tis. Kč
    • •
  • 60 tis. Kč
    • •
  • MZ
Project

Characterization of the Fur phenotype of mutants of Pseudomonas aeruginosa over-production of components of iron transport system. (KJB500200703)

Project deals with characterization of FeIII transport system, a factor of virulence, in Fur mutants of P. aeruginosa regarding application of knowledge in biotechnologies. Study is aimed at 1. relationship between overproduction of pyoverdi...

EE - Mikrobiologie, virologie

  • 2007 - 2009
    • •
  • 1 258 tis. Kč
    • •
  • 1 258 tis. Kč
    • •
  • AV ČR
Project

Combined phage therapy for supporting the treatment of chronic respiratory diseases. (FW10010112)

A mixture of antibiotics suitable for inhalation and lytic bacteriophages active against the species S. aureus and P. aeruginosa will be prepared and tested. Testing of the product will be provided together with Masaryk University (MU. a...

Infectious Diseases

  • 2024 - 2026
    • •
  • 9 755 tis. Kč
    • •
  • 6 821 tis. Kč
    • •
  • TA ČR
Project

Secondary metabolism in intracellular pathogens (LUAUS24214)

(i) Polymycovirus in a filamentous fungal cell (ii) Mycobacterium tuberculosis in a mammalian cell (iii) Bacteriophage Pf4 and its role in iron acquisition by a Pseudomonas aeruginosa cell (iv) Metal metabolism in the fungus Coc...

Analytical chemistry

  • 2024 - 2028
    • •
  • 9 631 tis. Kč
    • •
  • 9 631 tis. Kč
    • •
  • MŠMT
Project

Molecular identification of bacterial strains which cause severe epidemics in Czech patients with cystic fibrosis and prevention of their spread within this population (NS10543)

Over the project period, approximately 1000 clinical isolates of Pseudomonas aeruginosa recovered from 110 patients with cystic fibrosis (CF) and ca 700 isolates of Burkholderia cepacia complex from 80 CF patients will be genotyped ...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2009 - 2011
    • •
  • 4 687 tis. Kč
    • •
  • 4 687 tis. Kč
    • •
  • MZ
Project

Genetic characterization of chlorobenzoate degrading bacteria (GA204/99/D050)

This project deals with genetic characterization of chlorobenzoate strains isolated from the contaminated soil. First, new chlorobenzoate strains will be isolated, characterized and studied their degradation pathways. Ocbd genes responsible for degra...

EB - Genetika a molekulární biologie

  • 1999 - 2002
    • •
  • 894 tis. Kč
    • •
  • 651 tis. Kč
    • •
  • GA ČR
Project

Mass spectrometric quantification of volatile metabolites in breath for noninvasive diagnosis and monitoring of bacterial infection in cystic fibrosis (GA14-14534S)

Research of non-invasive methods for diagnosis and monitoring of bacterial infection in cystic fibrosis is currently a topic of great interest. Hydrogen cyanide has been identified as a breath biomarker of Pseudomonas aeruginosa (PA...

CB - Analytická chemie, separace

  • 2014 - 2016
    • •
  • 7 575 tis. Kč
    • •
  • 7 575 tis. Kč
    • •
  • GA ČR
Project

Structure-function studies on lectins and adhesins from microbial patogens (GA303/06/0570)

Oligosaccharide-mediated recognition and adhesion are key points in the early steps of infection of many pathogens. The project is focused mainly to structure-function studies of carbohydrate-binding proteins from Pseudomonas aeruginosa<...

CE - Biochemie

  • 2006 - 2008
    • •
  • 2 176 tis. Kč
    • •
  • 2 176 tis. Kč
    • •
  • GA ČR
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