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4 (0,105s)

Project

Effect and pharmacokinetics of methotrexate in the treatment of psoriasis (IZ2960)

FR - Farmakologie a lékárnická chemie

  • 1995 - 1997
  • 1 473 tis. Kč
  • 1 373 tis. Kč
  • MZ
Project

Changes in the microbiome composition as a risk factor in the development of psoriasis (NV15-30782A)

Affecting 2-3% of population, psoriasis is a chronic, autoimmune skin disease that involves dysregulated interplay between immune cells, keratinocytes and environmental triggers. We hypothesize that skin microbiome composition is the crucial aspect f...

FO - Dermatovenerologie

  • 2015 - 2018
  • 6 426 tis. Kč
  • 6 426 tis. Kč
  • MZ
Project

Personalized medicine approach based on analysis of immunity and microbiota interactions as a tool to predict therapeutic response in patients with psoriasis (NW24-06-00509)

Psoriasis is a chronic, systemic immune-mediated disease with complex pathogenesis and multiple comorbidities. Current evidence suggests that a combination of genetic and environmental factors, such as obesity, stress, and microbiota composition, can...

Dermatology and venereal diseases

  • 2024 - 2027
  • 11 273 tis. Kč
  • 11 273 tis. Kč
  • MZ
Project

The effect of anti IL-17 therapy on skin and gut microbiota and intestinal barrier function in psoriasis patients (NU22J-05-00056)

IL-17 inhibitors have recently emerged as effective and safe therapy for the treatment of severe psoriasis with a very rapid onset of action. Although IL-17 inhibitor therapy is considered safe, its use in psoriasis treatment has been occasionally as...

Immunology

  • 2022 - 2025
  • 6 524 tis. Kč
  • 6 524 tis. Kč
  • MZ
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