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4 (0,063s)

Project

Heterodendralene-based approach to isocoumarins and isolycoricidine (GA22-19209S)

The project is focused on the application of the reactivity of heterodendralenes, constructed on the pyranone structural scaffold to practical syntheses of biologically interesting natural products. The limited flexibility of the heterodendr...

Organic chemistry

  • 2022 - 2024
  • 6 489 tis. Kč
  • 6 489 tis. Kč
  • GA ČR
Project

Novel Dissonantly Disposed Dendralenes Synthesis and Reactivity (GA18-17868S)

of pyranone-based heterodendralenes and application in natural product synthesis are also...

Organic chemistry

  • 2018 - 2021
  • 5 358 tis. Kč
  • 5 358 tis. Kč
  • GA ČR
Project

Application of Pd-mediated processes in drug synthesis development of novel antifungals and cytostatics based on natural lactones (GA203/04/2134)

moiety is the main structural feature of some antifungally active natural pyranones...

CC - Organická chemie

  • 2004 - 2006
  • 1 381 tis. Kč
  • 1 381 tis. Kč
  • GA ČR
Project

Natural Lactones and Lactams Towards Diverse Biological Activities through Purposeful Synthetic Manipulations (GA15-07332S)

Based on their ability to selectively inhibit or activate proteins with strategic functions in living organisms, natural products have again started to play a major role in drug development. The project is thus focused on the synthesis and screening ...

CC - Organická chemie

  • 2015 - 2017
  • 4 908 tis. Kč
  • 4 908 tis. Kč
  • GA ČR
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