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Projects

689 projects (0,223s) •

Project

Effects of ligands on DNA damage induced by free radicals. (OC09012)

DNA attack by radical species produced by water radiolysis is the most and proteins. The main tool will be the theoretical simulation of radical attack to DNA. The existing stochastic model of DNA damage caused by ...

BO - Biofyzika

  • 2009 - 2011
    • •
  • 465 tis. Kč
    • •
  • 465 tis. Kč
    • •
  • MŠMT
Project

Effects of drugs on radiation induced damages of DNA (IAB1048901)

minimization of studied complexes (software SYBYL). Probabilities of radical attack totheThe project includes simulation of radiation attack on DNA complexes of free radicals produced by the radioation in DNA surr...

BO - Biofyzika

  • 1999 - 2000
    • •
  • 282 tis. Kč
    • •
  • 226 tis. Kč
    • •
  • AV ČR
Project

Radiation induced damage of DNA - protein complexes (IAA1048103)

The project includes theoretical simulation of radiation attack to DNA-protein complexes. Our model allows predicting the effectsof OH radicals produced by radiation radical diffusion) and Smoluchowski theory (radical

BO - Biofyzika

  • 2001 - 2003
    • •
  • 1 543 tis. Kč
    • •
  • 738 tis. Kč
    • •
  • AV ČR
Project

Radical catalysis of enzymatic and biomimetic polynuclear transition-metal active sites (GA18-13093S)

spectroscopic and electrochemical data, key radical SAM intermediates responsible for radical-mediated attack of diverse substrates will be investigated alongRadicals generated by redox-active transition metal cen...

Physical chemistry

  • 2018 - 2020
    • •
  • 4 437 tis. Kč
    • •
  • 4 161 tis. Kč
    • •
  • GA ČR
Project

Radiolytic damage of DNA bases (KJB4048401)

, nucleosides and short DNA oligomers. The diffusion of radicals produced by water radiolysis will be simulated by Monte Carlo technique, radical reactions with particular......

CE - Biochemie

  • 2004 - 2005
    • •
  • 278 tis. Kč
    • •
  • 278 tis. Kč
    • •
  • AV ČR
Project

Detection of Radicalisation in the context of population and soft targets protection from violent incidents (VI20192022117)

Project identifies and evaluates security threat of radicalisation and processes the sophisticated methods and measures for detection and prevention of this phenomena in the context of population and soft target protection. Further, the project ensur...

Sociology

  • 2019 - 2022
    • •
  • 6 355 tis. Kč
    • •
  • 6 355 tis. Kč
    • •
  • MV
Project

Eukaryotic cell membrane as a target site for environmental stress factors (ME 315)

Environmental stress factors cause primarily changes in the plasma membrane OF live cells. These cause secondarily pathological changes in plant, animal and human cells. These changes are largely due to oxygen radicals induced by stress subs...

EE - Mikrobiologie, virologie

  • 1999 - 2001
    • •
  • 1 136 tis. Kč
    • •
  • 500 tis. Kč
    • •
  • MŠMT
Project

Selective enzymatic oxidations and deracemizations of natural products and biomolecules (OC09045)

exposed to the oxidative/radical attack in the organism for elucidationof...

CC - Organická chemie

  • 2009 - 2012
    • •
  • 1 760 tis. Kč
    • •
  • 1 760 tis. Kč
    • •
  • MŠMT
Project

Mechanisms of antiradical activity of flavonolignan silybin and preparation of hybrid antioxidant compounds for potential application in medicine (KJB400200701)

to the final biological response. Radical oxidations of selectively protected derivatives on the most probable sites of the oxidative attack in a flavonolignan skeleton......

CC - Organická chemie

  • 2007 - 2009
    • •
  • 993 tis. Kč
    • •
  • 993 tis. Kč
    • •
  • AV ČR
Project

Adaptive protection against DDoS attacks (VI20192022137)

The project undertakes research into advanced protection against distributed denial of service attacks. Rapid adaptation to an evolving vector of attack, automation of user tasks, exploitation of external information resources are k...

Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)

  • 2019 - 2022
    • •
  • 19 846 tis. Kč
    • •
  • 19 846 tis. Kč
    • •
  • MV
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