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Projects

1 496 projects (0,152s)

Project

Analysis of genetic of hypertension and malformation syndrome in recombinant inbred rat-strains model. (PL548)

9F - 9

  • 1993 - 1995
  • 323 tis. Kč
  • 646 tis. Kč
  • MZ
Project

Pathogenesis of spontaneous hypertension integrated analysis of intermediary phenotypes of autonomic/sympathetic system and gene expression profiles in rat recombinant inbred strains (IAA500110604)

The metabolic syndrome is a very common precursor of cardiovascular disease. In the current project, we will analyze the role of autonomic intermediate phenotypes in the pathogenesis of metabolic syndrome using recombinant inbred (R...

EB - Genetika a molekulární biologie

  • 2006 - 2009
  • 2 872 tis. Kč
  • 2 872 tis. Kč
  • AV ČR
Project

Mapping of genetic determinants of spontaneous hypertension in recombinant inbred and congenic strains. (OK 210)

9H - 9

  • 1996 - 1996
  • 0 tis. Kč
  • 0 tis. Kč
  • MŠMT
Project

Genetic determinants of interstitial fibrosis and coronary microvascular remodelation (LH11049)

We will use histomorphometric analyses to determine the presence and extent of coronary microvascular remodeling and myocardial fibrosis in the BXH/HXB recombinant inbred strains derived from the spontaneously hypertensive ...

EB - Genetika a molekulární biologie

  • 2011 - 2014
  • 3 564 tis. Kč
  • 3 564 tis. Kč
  • MŠMT
Project

Mapping of genetic determinants of spontaneous hypertension in recombinant inbred and congenic strains of the rat (GA302/96/1282)

blood pressure, we have developed a unique set of recombinant inbred ( RI ) and congenic strains. These strains were derived from the spontaneously hypertensive rat, we have constructed a detailed map in RI st...

EB - Genetika a molekulární biologie

  • 1996 - 1998
  • 796 tis. Kč
  • 660 tis. Kč
  • GA ČR
Project

Systematic deconstruction of metabolic syndrome's genetic architecture by gene-expression profiling in a new set of recombinant inbred rat strains (GP303/05/P026)

to exploit the newly established set of recombinant inbred rat strains PXO in order of metabolicsyndrome. After the metabolic characterization of the PXO strains and their progenitors......

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2005 - 2007
  • 1 200 tis. Kč
  • 1 200 tis. Kč
  • GA ČR
Project

Genetic and correlation analysis of learning and memory processies in the art. (NF4795)

In rat recombinant inbred (RI) strains, we will perform a genetic and correlation analysis of phenotypes that encompass distinct types of the memory: we scans with more than 550 gene markers that are currently available in ...

FH - Neurologie, neurochirurgie, neurovědy

  • 1998 - 2000
  • 1 814 tis. Kč
  • 1 462 tis. Kč
  • MZ
Project

Genetic determinants of cardiac mass and response to infarction in recombinant inbred rats (GA301/06/0028)

Many cardiovascular (CV) phenotypes are quantitative traits determined by genetic and environmental factors. This project will characterize the genetic determinants of clinically important CV phenotypes in recombinant inbred (RI) ra...

EB - Genetika a molekulární biologie

  • 2006 - 2008
  • 3 582 tis. Kč
  • 3 582 tis. Kč
  • GA ČR
Project

Integrated microRNA, mRNA expression profiling, linkage and correlation analyses for identification of genes underlying complex traits (GAP301/10/0290)

BXH/HXB rat recombinant inbred strains to test the hypothesis that variability...

EB - Genetika a molekulární biologie

  • 2010 - 2014
  • 6 393 tis. Kč
  • 6 393 tis. Kč
  • GA ČR
Project

Genetic and correlation analyses of ectopic fat accumulation and adipose tissue oxidative/inflammatory processes and their role in the pathogenesis of insulin resistance (ME08006)

/inflammatory processes in the pathogenesis of insulin resistance in the BXH/HXB recombinant inbred strains derived from spontaneously hypertensive (SHR) and Brown Norway (BN......

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2008 - 2012
  • 2 500 tis. Kč
  • 2 500 tis. Kč
  • MŠMT
  • 1 - 10 out of 1 496