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3 614 (0,214s) •

Project

Transcriptional regulation of Eya1 gene (IAC5052011)

gene Eya1, which codes for the human homologue of the eyes absent (eya) gene be a target gene of transcription factor Pax6. To confirm this hypothesis we will isolate promoter/enhancer of Eya1 gene and its fragmen...

EB - Genetika a molekulární biologie

  • 2000 - 2000
    • •
  • 181 tis. Kč
    • •
  • 151 tis. Kč
    • •
  • AV ČR
Project

Regulation of posttranscriptional gene silencing in transgene plants (GP521/01/P042)

The aim of the proposed project is to study posttrancriptional gene silencing in transgenic plants. Tobacco lines containing a neomycin phosphotransferase II reporter gene (nptll) and showing variable degree of its silencin...

EB - Genetika a molekulární biologie

  • 2001 - 2003
    • •
  • 1 319 tis. Kč
    • •
  • 700 tis. Kč
    • •
  • GA ČR
Project

Molecular analysis of a gene trap insertion in mice (IAA5052802)

of the reporter lacZ or beta-geo genes can be monitored in ES cell-derived chimaeric embryos- and stage-specific expression of the beta-geo reporter gene in ES cell-derived chimaericGene trapping in mouse...

EB - Genetika a molekulární biologie

  • 1998 - 2000
    • •
  • 1 592 tis. Kč
    • •
  • 847 tis. Kč
    • •
  • AV ČR
Project

Regulation of the gene for muscarinic acetylcholine receptors of the M2 subtype (IAA5011306)

of the regulatory regions of the M2RG. Secondly, we will use reporter genes to identifyThe aim of the project is to identify the genomic regulatory elements responsible for directing cell specific expression of the mammalian M2 mus...

EB - Genetika a molekulární biologie

  • 2003 - 2005
    • •
  • 3 484 tis. Kč
    • •
  • 2 413 tis. Kč
    • •
  • AV ČR
Project

Development and validation of a suite of imaging reporters for plant hormones based on genetically encoded bioluminescence (GC21-20936J)

-dependent, influencing both gene expression and post-transcriptional events promotor elements that drive the expression of the marker gene, which is typically tracking the plant hormone-driven gene expression in the growth...

GM technology (crops and livestock), livestock cloning, marker assisted selection, diagnostics (DNA chips and biosensing devices for the early/accurate detection of diseases) biomass feedstock production technologies, biopharming

  • 2021 - 2023
    • •
  • 4 737 tis. Kč
    • •
  • 4 737 tis. Kč
    • •
  • GA ČR
Project

Investigating the developmental function of the BnaTAA1 gene family in Brassica napus (GA23-06140S)

to functionally study the BnaTAA1 gene family in B. napus, an allotetraploid species. We. This research will combine bioinformatics, expression analysis, reporter development transgenic plants. The same methodology will generate au...

Developmental biology

  • 2023 - 2025
    • •
  • 9 995 tis. Kč
    • •
  • 9 995 tis. Kč
    • •
  • GA ČR
Project

A-204C polymorphism and regulation of cholesterol 7alpha-hydroxylase activity (NR8987)

gene promoter. Circadian variation in CYP7A1 activity will be studied under basal conditions and after stimulation and inhibition of CYP7A1 gene expression using drugs (colestipol and chenodeoxycholic acid, respectively). The activ...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2006 - 2008
    • •
  • 3 917 tis. Kč
    • •
  • 3 599 tis. Kč
    • •
  • MZ
Project

Properties of horizontal mitochondrial transfer in cancer (GJ18-24753Y)

in the form of mitochondrial DNA (mtDNA). Cell type mtDNA heteroplasmy was reported before in healthy individuals. In parallel reports show that mitochondria move between mammalian model for in vivo and in vitro studies on mitochod...

Cell biology

  • 2018 - 2022
    • •
  • 5 898 tis. Kč
    • •
  • 5 898 tis. Kč
    • •
  • GA ČR
Project

Immune response genes in the horse (GA523/99/1152)

Genes known to be involved in immune responses in other species will be studied in the horse. Primers specific for different parts of such genes (exons, introns, promoters) will be done. Three types of genes are supposed to...

GI - Šlechtění a plemenářství hospodářských zvířat

  • 1999 - 2001
    • •
  • 3 132 tis. Kč
    • •
  • 3 132 tis. Kč
    • •
  • GA ČR
Project

Mechanisms of transcriptional pulsing (GA16-12611S)

mechanisms that are responsible for the pulsatile nature of gene activity remain transgenic nascent transcripts that can be detected by a PP7-GFP reporter of gene regulation.......

EB - Genetika a molekulární biologie

  • 2016 - 2017
    • •
  • 3 289 tis. Kč
    • •
  • 3 289 tis. Kč
    • •
  • GA ČR
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