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4 508 (0,094s)

Project

Mechanism(s) controlling sensitivity and/or resistance of cancer cell lines to anticancer analogues of vitamin E (GP204/09/P632)

cancer cell lines with acquired resistance to anticancer derivatives of vitamin E of acquired resistance or sensitivity of certain cell lines to ?-TOS or another toxic to cancercell lines than to normal c...

CE - Biochemie

  • 2009 - 2010
  • 624 tis. Kč
  • 624 tis. Kč
  • GA ČR
Project

Tunnel lining reinforced with composite materials with increased durability and resistance (CK04000283)

intended for tunnel lining fully reinforced with GFRP reinf. This segment. The solution is resistant to the effects of stray currents, or suitable for their interruption. Important aspect will be also the development of the tunnel ...

Construction engineering, Municipal and structural engineering

  • 2023 - 2026
  • 18 213 tis. Kč
  • 12 045 tis. Kč
  • TA ČR
Project

In-vitro study of molecular-genetic cuase of cell resistance against selected drugs (1A8696)

resistance (among the known as MDR1, MRP1 or BCRP) and possible genetic predisposing factors. By comparing the gene expression profile of both the parental and resistant cell-line, the specific role of ABC transporters in ...

EB - Genetika a molekulární biologie

  • 2005 - 2008
  • 7 196 tis. Kč
  • 6 751 tis. Kč
  • MZ
Project

Application of conventional and molecular genetic approaches for the development of grain legumes resistant to viral and fungal pathogens and insect pests. (QI91A229)

The objective of the proposal is the development of pea and faba bean lines resistant to viral and fungal pathogens and insect pests (pyramiding of several resistance genes). For the production of lines utilizable ...

GE - Šlechtění rostlin

  • 2009 - 2013
  • 17 544 tis. Kč
  • 15 567 tis. Kč
  • MZe
Project

Mechanisms of resistance of tumor cells lines and breast cancer to chemotherapy by taxanes and possibilities of intervention (NL6715)

Therole role P-glycoprotein, important factor of multidrug resistence, on therapy will be followed in resistant vs.sensitive tumor lines in connection with efflux of taxanes of taxanes will be studied in tumor lines

FD - Onkologie a hematologie

  • 2001 - 2003
  • 6 694 tis. Kč
  • 2 648 tis. Kč
  • MZ
Project

The analysis of rapeseed resistance to viral pathogens (TM01000044)

, with respect to changing climate and plant resistance to viral pathogens. The aim is also to identify resistant rapeseed genotypes, including the development of doubled haploid (DH) rapeseed lines resistant to th...

Agronomy, plant breeding and plant protection; (Agricultural biotechnology to be 4.4)

  • 2020 - 2022
  • 7 446 tis. Kč
  • 5 460 tis. Kč
  • TA ČR
Project

Winter crop breeding for resistance to stress temperatures and drought (EP9141)

are following: 1/ use of in vitro selection method of resistant wheat and barley lines, 2/ the effectiveness of gliadin signal genes of winter resistance in wheat, 3/ use of dihaploids for evaluation and selection of frost...

GE - Šlechtění rostlin

  • 1999 - 2002
  • 2 700 tis. Kč
  • 1 800 tis. Kč
  • MZe
Project

Biotechnology tools for improving disease resistance and seed quality in legumes (7D09001)

The object of this project is the progress of transgenetic line of peas with improved resistence toward fungi pathogenes, insect pest and inreased seed yield. Eventual transgenetic lines will have new signs, required by bre...

EB - Genetika a molekulární biologie

  • 2009 - 2011
  • 3 277 tis. Kč
  • 1 966 tis. Kč
  • MŠMT
Project

The protection of strawberry plants against plant pathogen of Phytophthora sp. (QK1710377)

Evaluation of the presence of particular P. cactorum genetic lines. cactorum lines sensitivity to fungicides. Evaluation of particular strawberry varieties resistance to P. cactorum. Evaluation of possibility to use biologi...

GF - Choroby, škůdci, plevely a ochrana rostlin

  • 2017 - 2021
  • 10 004 tis. Kč
  • 10 004 tis. Kč
  • MZe
Project

Analysis and suppression of mechanisms leading to the resistance of cancer cells to TRAIL. (LH12202)

1. Characterization and targeting of main resistance mechanism(s) to TRAIL-induced apoptosis in model cancer-derived cell lines of breast, colon and pancreatic of the recombinant ligand TRAIL analysis of their signaling in the model...

EB - Genetika a molekulární biologie

  • 2012 - 2014
  • 4 800 tis. Kč
  • 4 800 tis. Kč
  • MŠMT
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