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63 (0,122s) •

Project

The evaluation of the sensitivity of different score systems used for the assessment of rheumatoid arthritis progression (NR8454)

Using two imaging algorithms - classical skiagraphy and magnetic resonance imaging, - the progression of morphological changes will be evaluated in early rheumatoid arthritis. Also, prognostic indicators of these changes will be defined. The...

FE - Ostatní obory vnitřního lékařství

  • 2005 - 2007
    • •
  • 4 227 tis. Kč
    • •
  • 3 958 tis. Kč
    • •
  • MZ
Project

Prolactin and rheumatoid arthritis (NR9292)

I: Prolactin participates in the etiopathogenesis of autoimmune disorders. II: Prolactin is producted by inflammation-activated peripheral blood cells. III: Several works are available which evidence its presence in the synovial fluid and correlation...

FE - Ostatní obory vnitřního lékařství

  • 2007 - 2009
    • •
  • 3 616 tis. Kč
    • •
  • 3 459 tis. Kč
    • •
  • MZ
Project

Study on association between intestinal microbiome and increased risk of chronic inflammatory diseases of locomotor system, osteoporosis and rheumatoid arthritis. (NV18-05-00394)

for osteoporosis and rheumatoid arthritis. The aim of this study is to test our hypothesis consequences, increased risk of osteoporosis and rheumatoid arthritis. Hormone therapy of bone loss, but also progression of rheumatoid<...

General and internal medicine

  • 2018 - 2022
    • •
  • 13 802 tis. Kč
    • •
  • 13 776 tis. Kč
    • •
  • MZ
Project

The role of selected chemokine receptors and interferone-beta in the pathogenesis of rheumatoid arthritis (NI6459)

Identification of the role for CXCR3 and CCR5 and their ligands in the synovial tissue of patients with early rheumatoid arthritis. Exploration of the role of interferon beta in the synovial inflammation and assessment of its suppresive effe...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2001 - 2003
    • •
  • 3 146 tis. Kč
    • •
  • 3 120 tis. Kč
    • •
  • MZ
Project

Dipeptidyl peptidase IV activity and/or structure homologues (DASH) in rheumatoid and psoriatic arthritides. Pathogenetic and diagnostic relevance of new group of regulatory molecules? (NK7746)

Studies of selected "dipeptidyl peptidase IV activity and/or structure homologues (DASH)" in blood plasma and mononuclear cells during the developement of rheumatoid and psoriatic arthritides.......

FE - Ostatní obory vnitřního lékařství

  • 2003 - 2005
    • •
  • 3 113 tis. Kč
    • •
  • 3 113 tis. Kč
    • •
  • MZ
Project

Evaluation of function, quality of life and therapy cost in most frequent rheumatoid diseases (NK6802)

Validization of functional questionaires into czech language will be carry out as follows: HAQ for rheumatoid arthritis; WOMAC for osteoarthritis; BAS-G ankylosing spondylitis; SF36 and EQ-5D.......

FE - Ostatní obory vnitřního lékařství

  • 2001 - 2003
    • •
  • 1 965 tis. Kč
    • •
  • 1 953 tis. Kč
    • •
  • MZ
Project

Local and systemic pathogenetic role of "DASH system" molecules in rheumatoid arthritis (NR9273)

The project is designed to analyze relationships among Dipeptidyl peptidase-IV activity and/or structure homologous molecules, their biologically active substrates and related receptors, relevant for development, progression, diagnostics and therapy ...

FE - Ostatní obory vnitřního lékařství

  • 2007 - 2009
    • •
  • 3 538 tis. Kč
    • •
  • 3 489 tis. Kč
    • •
  • MZ
Project

Diagnostic and prognostic role of micro RNA (miR) expression profile in rheumatoid arthritis (NT14498)

Monitoring of circulating miR represents a potential diagnostic and prognostic marker of several cancers. Circulating miR in peripheral blood and synovial fluid in patients with rheumatoid arthritis has been discovered recently, and therefor...

FP - Ostatní lékařské obory

  • 2013 - 2015
    • •
  • 5 778 tis. Kč
    • •
  • 5 778 tis. Kč
    • •
  • MZ
Project

Comparison of efficacy of cemented and non cemented and non cemented knee arthroplasty by patients with rheumatoid arthritis and juvenile rheumatoid arthritis. (IZ2916)

FJ - Chirurgie včetně transplantologie

  • 1995 - 1997
    • •
  • 1 540 tis. Kč
    • •
  • 1 540 tis. Kč
    • •
  • MZ
Project

The molecules regulating osteoclast differentiation and their contribudion in rheumatoid arthritis bone resorption (NK7293)

The relation of local and systemic expression of RANKL on T lymphocytes and the RANK and RANKL ewpression on synovial tissue cells will be studied by immunohistochemisty and flow cytometry in patients with active rheumatoid arthritis and ost...

FE - Ostatní obory vnitřního lékařství

  • 2002 - 2004
    • •
  • 3 260 tis. Kč
    • •
  • 3 246 tis. Kč
    • •
  • MZ
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