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673 (0,102s) •

Project

Supramolecular approach to saccharide-mediated cell surface recognition (GA203/06/1038)

Proposal concerns with design, synthesis and binding study of novel saccharide porhyrins and calixphyrins. Saccharide binding site rely on phosphate, phosphonate important saccharides will be tested and the most promising s...

CC - Organická chemie

  • 2006 - 2008
    • •
  • 3 990 tis. Kč
    • •
  • 3 990 tis. Kč
    • •
  • GA ČR
Project

Specific ligands for saccharide tumor markers from recognition to diagnoses and therapy (LH14008)

Preparation and study of specific ligands (polymethinium salts, porphyrin and lanthanide complexes) for tumor saccharide markers (glycoproteins, glycolipids and others) and their diagnostic and therapeutic applications.......

FR - Farmakologie a lékárnická chemie

  • 2014 - 2016
    • •
  • 1 678 tis. Kč
    • •
  • 1 678 tis. Kč
    • •
  • MŠMT
Project

Calixarene-based multivalent glyco-druge - design, structure, biological (antitumor and antiviral) activity (IAA400200503)

New water soluble ligands will be designed. The calix[n]arene scaffold in different (semi)rigid conformations, and saccharides, glycopeptides, glykosaminoacids and glycodendrons will be used as biomolecules. Computation methods (mol. dynamic...

CC - Organická chemie

  • 2005 - 2009
    • •
  • 5 028 tis. Kč
    • •
  • 5 028 tis. Kč
    • •
  • AV ČR
Project

The importance of lectin-saccharide interactions of Eisenia foetida cytolytic factor CCF with ion channels for tumorilytic activity (GA310/02/1437)

We have identified, characterized, and cloned a defense antimicrobial lectin CCF, which is present in the coelomic fluid and on the surface of immunocytes of Eisenia foetida earthworms (Annelida), This lectin acts as a "pattern recognition t...

EC - Imunologie

  • 2002 - 2004
    • •
  • 3 254 tis. Kč
    • •
  • 1 575 tis. Kč
    • •
  • GA ČR
Project

Comparative structural and saccharide content analyses of conifer somatic and zygotic embryogeneses (1P05OC038)

study of dynamics of the content of saccharides, lipides, proteines, anatomic and morfological analysis...

EB - Genetika a molekulární biologie

  • 2005 - 2005
    • •
  • 227 tis. Kč
    • •
  • 122 tis. Kč
    • •
  • MŠMT
Project

Biological role of lectins in symbiosis and pathogenicity (GA21-29622S)

Protein-saccharide recognition plays a crucial role in many biological processes, like cell adhesion, receptor activation, signal transduction, differentiation or recognition of host tissues by pathogens. The proposed proje...

Biochemistry and molecular biology

  • 2021 - 2023
    • •
  • 8 846 tis. Kč
    • •
  • 8 846 tis. Kč
    • •
  • GA ČR
Project

Saccharide based hydrophilic polymers for medical applications (IAA4050301)

Preparation of hydrophilic polymer systems based on polymerizable saccharide derivatives. Saccharide derivatives will be prepared, beside standard laboratory protocols, newly formulated transacetalization reaction. Both soluble and ...

CD - Makromolekulární chemie

  • 2003 - 2005
    • •
  • 3 106 tis. Kč
    • •
  • 2 196 tis. Kč
    • •
  • AV ČR
Project

The development of screening micromethods and the development of a device for specific determination of carbohydrates in food with the aim to prove the quality and originality of used raw materials. (EP9410)

quality evaluation of the saccharide compositionand for proofs of suspected falsity such as using of unexpensive sweeteners instead of native saccharides in fruit juices. The aim of this project is to develop a method for determina...

GM - Potravinářství

  • 1999 - 2002
    • •
  • 1 400 tis. Kč
    • •
  • 700 tis. Kč
    • •
  • MZe
Project

Determination of structural saccharides digestibility of individual feeds in mixed rations of high-yielding cows. (EP0960996555)

The aim of this project is digestibility of structural saccharides of individual feeds, when mixed ration is fed to high-yielding cows. For this purpose nylon capsule method will be used. This method is original, this one was developed in VÚ...

GH - Výživa hospodářských zvířat

  • 1996 - 1999
    • •
  • 7 040 tis. Kč
    • •
  • 7 040 tis. Kč
    • •
  • MZe
Project

Comparative structural and saccharide content analyses of conifer somatic and zygotic embryogeneses (OC 843.40)

embryogenesis of both species will be studied for comparison. Endogenous saccharide contents cultivation conditions, histochemical localisation of saccharide-metabolism enzymes......

EI - Biotechnologie a bionika

  • 2000 - 2005
    • •
  • 5 741 tis. Kč
    • •
  • 2 260 tis. Kč
    • •
  • MŠMT
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