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62 (0,119s) •

Project

The effect of tick saliva on the transmission of the Lyme disease causative agent Borrelia burgdorferi (GA524/99/D035)

Tick saliva, due to its antihaemostatic, vasodilatory and immunosuppressive to a vertebrate host. The effect of tick saliva on mechanisms of nonspecific resistance the effect of saliva on immunity to tick-transmitted pathog...

EC - Imunologie

  • 1999 - 2002
    • •
  • 298 tis. Kč
    • •
  • 298 tis. Kč
    • •
  • GA ČR
Project

Effect of tick saliva on the transmission of Borrelia burgdorferi (GA524/02/0901)

Tick saliva, due to its anti-haemostatic, vasodilatory and immunomodulatory-borne pathogens. The general effect of tick saliva on host immune mechanisms has by tick saliva.The effect of tick saliva on the proliferation of B...

EC - Imunologie

  • 2002 - 2004
    • •
  • 3 340 tis. Kč
    • •
  • 2 540 tis. Kč
    • •
  • GA ČR
Project

Effect of tick saliva on signalling pathways activated by Borrelia pathogen in dendritic cells (GAP302/12/2208)

Tick saliva contains immunomodulatory molecules which facilitate both, blood of tick saliva and derived recombinant proteins on dendritic cell signalling pathways polarization of host immune response, the events related to saliv...

EC - Imunologie

  • 2012 - 2015
    • •
  • 7 315 tis. Kč
    • •
  • 5 843 tis. Kč
    • •
  • GA ČR
Project

IMMUNOMODULATORY EFFECTS OF TICK CYSTATINS (KJB500960702)

Tick saliva has been proven to facilitate transmission of important human the general effect of tick saliva on host immune mechanisms was characterised, little is known aboutimmunomodulatory functions of particular components in tic...

EC - Imunologie

  • 2007 - 2009
    • •
  • 1 350 tis. Kč
    • •
  • 1 350 tis. Kč
    • •
  • AV ČR
Project

Tick saliva-activated transmission of important pathogens (GA524/05/0811)

Tick saliva has been proven to facilitate transmission of important human several candidate molecules for this saliva-activated transmission (SAT) were proposed, none havebeen identified. Whereas the general effect of tick saliv...

EC - Imunologie

  • 2005 - 2007
    • •
  • 2 850 tis. Kč
    • •
  • 2 850 tis. Kč
    • •
  • GA ČR
Project

The effect of tick saliva and salivary sialostatins on cellular stres responses and its implication to tick-borne enecephalitis virus transmission (GA19-15678S)

showed that vector saliva support transmission of tick-borne pathogens, including flaviviruses. Proposed research brings a novel insight into the role that saliva plays in this process. We suggest that saliva from the tick...

Virology

  • 2019 - 2022
    • •
  • 6 516 tis. Kč
    • •
  • 6 395 tis. Kč
    • •
  • GA ČR
Project

Functional characterization of cytokine binding molecules from tick saliva (GN23-07242I)

. Ticks secrete saliva containing hundreds of proteins that interfere with all types and data obtained with I. ricinus saliva is, that I. ricinus ticks secrete cytokine binding proteins in their saliva. These molecules can ...

Biochemistry and molecular biology

  • 2023 - 2026
    • •
  • 5 916 tis. Kč
    • •
  • 5 916 tis. Kč
    • •
  • GA ČR
Project

The Role of Genetic Factors of the Vertebrate Host and the Phlebotomine Vector in the Susceptibility to Leishmania major (IZ4122)

Recombinant congenic strains will be used to map the genes controlling susceptibility to Leishmania major. We will study their interaction with the Phlebotomus saliva. The active component of the saliva will be isolated.......

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 1997 - 1999
    • •
  • 2 204 tis. Kč
    • •
  • 1 604 tis. Kč
    • •
  • MZ
Project

Effect of tick saliva cystatins on Th9 cells and the development of experimental asthma (GCP302/11/J029)

facilitating both blood feeding and tick-borne pathogen transmission. Tick saliva contains. In our pilot experiments we have shown that Ixodes ricinus tick saliva and cystatin from saliva of the related tick I. scapularis ...

EC - Imunologie

  • 2011 - 2015
    • •
  • 4 824 tis. Kč
    • •
  • 4 824 tis. Kč
    • •
  • GA ČR
Project

Immunomodulation activity in sand fly saliva (Diptera Phlebotominae) (GP206/06/P015)

In this project I would like to obtain the basic data about the host immunity in response to sand fly saliva. Sand flies are the vectors of Leishmania parasites - and their saliva plays an important role during the first steps of in...

EC - Imunologie

  • 2006 - 2008
    • •
  • 1 084 tis. Kč
    • •
  • 1 084 tis. Kč
    • •
  • GA ČR
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