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3 191 (0,153s) •

Project

The relationship between nutrition and secretion of adipocytokines and other proteins in adipose tissue (NR9161)

and secretion of proposed proteins contributed to the pathogenesis of metabolicsyndrome. 2. to what degree is it possible to effect alternative secretion of these proteins, it will be established new methods for o...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2007 - 2009
    • •
  • 3 958 tis. Kč
    • •
  • 3 629 tis. Kč
    • •
  • MZ
Project

Signalling during Pollen-Pistil interaction preceding fertilization; the role of short- and long-distance secreted signals of fertilization (GA15-22720S)

among the identified pollen tube secreted proteins. Their secretion was largely the signaling role undertaken by identified secreted proteins during pollen tube-ovule gametophyte conveyed by secreted<...

ED - Fyziologie

  • 2015 - 2017
    • •
  • 7 968 tis. Kč
    • •
  • 7 968 tis. Kč
    • •
  • GA ČR
Project

Proteomic characterization of cell membrane surface proteins, secretome and exosomes in human cell based Huntington’s disease model. (LTC18079)

and secreted proteins of neural stem cells (NSCs) in the presence of mutant huntingtin (mHTT) protein and also changes in proteome and miRNA composition of exosomes secreted by these cells. This will bring new kno...

Neurosciences (including psychophysiology)

  • 2018 - 2021
    • •
  • 5 309 tis. Kč
    • •
  • 4 525 tis. Kč
    • •
  • MŠMT
Project

Regulation of adipocytokines and other proteins production in adipose tissue of health and obese subjects in vivo (GA303/07/0840)

intermediary mechanisms is the altered secretion of proteins produced in adipose tissue-coagulation factors ect. The increased secretion of adipocytokines creates the view of proinflammatory state of the organism. Up to da...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2007 - 2009
    • •
  • 2 864 tis. Kč
    • •
  • 2 864 tis. Kč
    • •
  • GA ČR
Project

Uncovering the role of diacylglycerols in regulation of insulin secretion from β-cells (GA19-21318S)

DAG-binding proteins involved in regulation of insulin secretion. To addressβ-Cell failure leading to insufficient secretion of insulin is central secretion regulation by these lipids are still poorly understood. ...

Endocrinology and metabolism (including diabetes, hormones)

  • 2019 - 2020
    • •
  • 2 671 tis. Kč
    • •
  • 2 497 tis. Kč
    • •
  • GA ČR
Project

Molecular mechanism of protein translocation through the bacterial Type I secretion system (GA15-11851S)

that improves the kinetics of ATP-energized secretion of RTX proteins. The proposed researchType I secretion system (T1SS) of Gram-negative bacteria allows secretion) proteins characterized by the C-termi...

EE - Mikrobiologie, virologie

  • 2015 - 2017
    • •
  • 7 053 tis. Kč
    • •
  • 7 053 tis. Kč
    • •
  • GA ČR
Project

Improvement of the diagnostics of disorders of growth hormone secretion with the follow- up of growth hormone binding protein and IGF-binding protein 3 (IZ2344)

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 1994 - 1997
    • •
  • 589 tis. Kč
    • •
  • 706 tis. Kč
    • •
  • MZ
Project

Interplay of MLO and exocyst complex proteins in localized secretion in plant cells (GC19-02242J)

Mechanisms of the targeted secretion as a part of cell polarity processes the molecular mechanism of MLO protein activity in the context of exocyst function to uncover new functional aspects of MLO proteins. As MLO prot...

Cell biology

  • 2019 - 2023
    • •
  • 5 579 tis. Kč
    • •
  • 5 579 tis. Kč
    • •
  • GA ČR
Project

Induction and inhibition of isoenzymes of the aspartic proteinases secreted by the yeast belonging to the genus Candida (GA303/98/P252)

proteins and immunoglobulins. Therefore, the secreted aspartic proteinases proteinases secreted by the Candida yeast are believed to act as one of the virulence to design and synthesis of efficient and selective inhibitors...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 1998 - 2001
    • •
  • 762 tis. Kč
    • •
  • 720 tis. Kč
    • •
  • GA ČR
Project

Exploring the structure function relationship of membrane-pore-forming FGF2 oligomers - a single molecule approach (GC20-01401J)

-induced angiogenesis. As opposed to the majority of extracellularly localized proteins, FGF2 is secreted from cells by direct protein translocation across the plasma of a protein ATP1A1 in initiating oligomerizati...

Biophysics

  • 2020 - 2022
    • •
  • 4 953 tis. Kč
    • •
  • 4 616 tis. Kč
    • •
  • GA ČR
  • 1 - 10 out of 3 191