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283 (0,465s) •

Project

The relationship between nutrition and secretion of adipocytokines and other proteins in adipose tissue (NR9161)

In group of 20 obese women it will be observed secretion of adipocytokines and secretion of proposed proteins contributed to the pathogenesis of metabolicsyndrome. 2. to what degree is it possible to effect alternative secretion...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2007 - 2009
    • •
  • 3 958 tis. Kč
    • •
  • 3 629 tis. Kč
    • •
  • MZ
Project

Pathogenic Candida strains typing and characterization of secreted proteinases (NI6485)

Candida isolates from routine clinical screening will be identified, typed by RAPD and screened for secreted proteinase production. Odds method will be modified for rapid monitoring of proteinase secretion by Candida cultures. Inhib...

EE - Mikrobiologie, virologie

  • 2001 - 2003
    • •
  • 1 765 tis. Kč
    • •
  • 1 297 tis. Kč
    • •
  • MZ
Project

Induction and inhibition of isoenzymes of the aspartic proteinases secreted by the yeast belonging to the genus Candida (GA303/98/P252)

proteinases secreted by the Candida yeast are believed to act as one of the virulence proteins and immunoglobulins. Therefore, the secreted aspartic proteinases to design and synthesis of efficient and selective inhibitors of Candi...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 1998 - 2001
    • •
  • 762 tis. Kč
    • •
  • 720 tis. Kč
    • •
  • GA ČR
Project

Regulation of the insulin secretion in polycystic ovary syndrome (NR8759)

Polycystic ovary syndrome (PCOS) is connected with insulin resistance and with disturbed insulin secretion , but the literary data are discrepant. Complex evaluation) arginine test (secretion of insulin and glucagone) and oGTT (...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2006 - 2008
    • •
  • 4 918 tis. Kč
    • •
  • 4 565 tis. Kč
    • •
  • MZ
Project

The role of adipocytokines and fatty acids in the disorders of insulin sensitivity and insulin secretion in metabolic syndrome (NR9387)

This project is designed to assess the role of secretion products of adipose tissue, nonesterified fatty acids and adipocytokines, in the development of peripheral tissue insulin resistance and insulin secretion and to establish new...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2007 - 2009
    • •
  • 5 133 tis. Kč
    • •
  • 5 119 tis. Kč
    • •
  • MZ
Project

Signalling during Pollen-Pistil interaction preceding fertilization; the role of short- and long-distance secreted signals of fertilization (GA15-22720S)

gametophyte conveyed by secreted ligand molecules. We have reconstructed tobacco pollen groups representing secreted ligands and receptor of the pollen tubes. Their analysis pathways including small GTPase-mediated signal transduct...

ED - Fyziologie

  • 2015 - 2017
    • •
  • 7 968 tis. Kč
    • •
  • 7 968 tis. Kč
    • •
  • GA ČR
Project

Callose synthases - dynamics and mechanisms of secretion. (GA18-12579S)

the fact that specific localization and rapid secretion are essential for their function. In our previous project, we showed that callose synthase secretion to focus in detail on secretion of callose synthases during mecha...

Plant sciences, botany

  • 2018 - 2023
    • •
  • 4 949 tis. Kč
    • •
  • 4 949 tis. Kč
    • •
  • GA ČR
Project

Uncovering the role of diacylglycerols in regulation of insulin secretion from β-cells (GA19-21318S)

β-Cell failure leading to insufficient secretion of insulin is central secretion regulation by these lipids are still poorly understood. In this project we aim to elucidate the role of DAGs in regulation of insulin secretion

Endocrinology and metabolism (including diabetes, hormones)

  • 2019 - 2020
    • •
  • 2 671 tis. Kč
    • •
  • 2 497 tis. Kč
    • •
  • GA ČR
Project

Proteomic characterization of cell membrane surface proteins, secretome and exosomes in human cell based Huntington’s disease model. (LTC18079)

and secreted proteins of neural stem cells (NSCs) in the presence of mutant huntingtin secreted by these cells. This will bring new knowledge about developmental changes technology combined with LC-MS analysis. Specific Aim 2: Ana...

Neurosciences (including psychophysiology)

  • 2018 - 2021
    • •
  • 5 309 tis. Kč
    • •
  • 4 525 tis. Kč
    • •
  • MŠMT
Project

Molecular mechanism of protein translocation through the bacterial Type I secretion system (GA15-11851S)

Type I secretion system (T1SS) of Gram-negative bacteria allows secretion in secretion of RTX toxins across the bacterial cell envelope. Three-dimensional structures of the RTX repeats concomitantly to its export through th...

EE - Mikrobiologie, virologie

  • 2015 - 2017
    • •
  • 7 053 tis. Kč
    • •
  • 7 053 tis. Kč
    • •
  • GA ČR
  • 1 - 10 out of 283