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6 (0,102s)

Project

Screening of mutations in the PKD2 gene from families with autosomal dominant polycystic kidney disease. (NE5996)

Analysis of mutations in PKD2 gene in selected families with ADPKD by screening methods (SSCP,HA,DGGE) and following sequenation of positive fragments. Analysis of mutations in PKD2 gene is the only temporary available method in diferentiald...

FE - Ostatní obory vnitřního lékařství

  • 2000 - 2002
  • 3 422 tis. Kč
  • 3 420 tis. Kč
  • MZ
Project

Utilisation of genetical analysis to the diagnostics of human cytomegalovirus infection in immunodeficient patients (NR9418)

A) Genotyping of CMV strains identified in clustered cases of CMV infection in hematopoietic stem cell transplant recipients treated in Inst.Hematol. Blood Transfussion during the period 2004-5 using methods of RFLP analysis of gB gene UL55 and s...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2007 - 2009
  • 2 867 tis. Kč
  • 2 599 tis. Kč
  • MZ
Project

Primary ciliary dyskinesia new approaches to diagnostics and epidemiology (NT11469)

on RNA sequenation should became a part of the diagnostic protocol....

FG - Pediatrie

  • 2010 - 2014
  • 6 588 tis. Kč
  • 6 588 tis. Kč
  • MZ
Project

Study of the HNF-1 beta expression, epigenetic changes and mutations in tumors and non-tumorous lesions of the female genital tract (NT14001)

islands. Detection of mutation HNF-1 beta gene will be performed by sequenation...

FP - Ostatní lékařské obory

  • 2013 - 2015
  • 3 953 tis. Kč
  • 3 953 tis. Kč
  • MZ
Project

Origin and evolution of sex chromosomes in spiders (GA16-10298S)

Our project is focused on the evolution of spider sex chromosomes (i.e. gonosomes). A notable feature of spiders is the predominance of unusual multiple X chromosomes. Origin of these elements is unclear. Our data show considerable complexity of spid...

EB - Genetika a molekulární biologie

  • 2016 - 2020
  • 12 778 tis. Kč
  • 12 475 tis. Kč
  • GA ČR
Project

Explaining metastatic potential of colorectal cancer through whole-exome sequening and immune cell and telomere landscape (GA23-05609S)

The project uses an internationally unique set of colorectal cancer (CRC) samples (N=100) with liver metasta-ses from the same patients to carry out whole exome sequencing (WES). We search for critical mutations and mutation signatures that are assoc...

Oncology

  • 2023 - 2025
  • 12 109 tis. Kč
  • 12 109 tis. Kč
  • GA ČR
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