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6 103 (0,11s) •

Project

Spectroscopy of Single-Molecule Magnets Using Graphene-Based Bolometers (LTAUSA19060)

The goal of this project is to study nanostructured single-molecule magnets. These single-molecule magnets will be deposited directly onto graphene quantum dots and irradiated by terahertz radiation. This approach ...

Atomic, molecular and chemical physics (physics of atoms and molecules including collision, interaction with radiation, magnetic resonances, Mössbauer effect)

  • 2020 - 2022
    • •
  • 5 508 tis. Kč
    • •
  • 5 508 tis. Kč
    • •
  • MŠMT
Project

Photon-upconversion labeling for microfluidic single-molecule immunoassays of protein biomarkers (GA21-03156S)

The project proposes a new development of single-molecule immunoassays using, the counting of the single analyte molecules is possible. The innovation is based on using consumption, detection limits, and f...

Analytical chemistry

  • 2021 - 2024
    • •
  • 7 360 tis. Kč
    • •
  • 7 360 tis. Kč
    • •
  • GA ČR
Project

Observing single-molecule pirouettes (GA25-16414S)

The ability to measure the dynamics of biological processes at the single-molecule level is essential to unraveling complex living systems. In processes such as enzymatic unwinding of DNA, the displacements of the involved molec...

Optics (including laser optics and quantum optics)

  • 2025 - 2028
    • •
  • 5 994 tis. Kč
    • •
  • 5 994 tis. Kč
    • •
  • GA ČR
Project

Super resolution (single molecule fluorescent) microscopy for detecting interactions between membrane proteins present at low level (8J22AT012)

1) Develop a method allowing to detect interactions of membrane proteins at the single molecule level. 2) To analyse the multimeric state of S. cerevisiae membrane proteins Trk1/2 and Kch1/2 which are involved in cation ho...

Cell biology

  • 2022 - 2023
    • •
  • 144 tis. Kč
    • •
  • 144 tis. Kč
    • •
  • MŠMT
Project

Novel anti-Stokes lanthanide nanoparticles and multicolor FRET mechanisms for single-molecule DNA sequencing (GF23-06199K)

) that have a genetic component. Although a few DNA sequencing methods exist, detecting the activity of a single DNA polymerase molecule by fluorescence microscopy) system in combination with single DNA polymerase ...

Technologies involving identifying the functioning of DNA, proteins and enzymes and how they influence the onset of disease and maintenance of well-being (gene-based diagnostics and therapeutic interventions [pharmacogenomics, gene-based therapeutics])

  • 2023 - 2025
    • •
  • 6 525 tis. Kč
    • •
  • 6 525 tis. Kč
    • •
  • GA ČR
Project

Surpassing the Diffraction Limit in Label-Free Microscopy (LL2409)

. The proposed method is based on the detection and three-dimensional localization of all (resolvable) fluctuations associated with interacting single biomolecules. I leverage interferometric scattering microscopy (iSCAT) to det...

Optics (including laser optics and quantum optics)

  • 2024 - 2026
    • •
  • 24 416 tis. Kč
    • •
  • 24 416 tis. Kč
    • •
  • MŠMT
Project

Analysis of molecular signaling in individual cells of tissue structures (GA17-01995S)

detection of distributions of specific molecules in complex intracellular structures and immunofluorescence probes for sensitive and selective detection of signaling molecules culture and simultaneous single

CB - Analytická chemie, separace

  • 2017 - 2019
    • •
  • 3 820 tis. Kč
    • •
  • 3 529 tis. Kč
    • •
  • GA ČR
Project

Preparation of discrete photon-upconversion nanoparticle bioconjugates (LD15023)

for the single molecule detection of protein markers (prostate specifc antigen). Such single molecule experiments are only feasible if no nanoparticle aggregation occurs and well-defined bioconjugates are...

CB - Analytická chemie, separace

  • 2016 - 2017
    • •
  • 1 263 tis. Kč
    • •
  • 1 263 tis. Kč
    • •
  • MŠMT
Project

Sensors and Detectors for Future Information Society (EH22_008/0004596)

The aim of the project is to implement planned research projects that will achieve international excellence in quality and originality. Within the framework of capacity development of research teams, a team will be assembled to focus on research acti...

Optics (including laser optics and quantum optics)

  • 2024 - 2028
    • •
  • 499 689 tis. Kč
    • •
  • 126 420 tis. Kč
    • •
  • MŠMT
Project

Luminiscence and vibrations of molecular circuits (GA20-18741S)

Functional blocks made of single molecules are the ultimate frontier of the molecule. The project aims on fundamental laws governing such model single-molecular interesting classes of single-molecular devi...

Atomic, molecular and chemical physics (physics of atoms and molecules including collision, interaction with radiation, magnetic resonances, Mössbauer effect)

  • 2020 - 2022
    • •
  • 11 189 tis. Kč
    • •
  • 11 189 tis. Kč
    • •
  • GA ČR
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