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407 (0,107s) •

Project

Changes in the microbiome composition as a risk factor in the development of psoriasis (NV15-30782A)

Affecting 2-3% of population, psoriasis is a chronic, autoimmune skin disease that involves dysregulated interplay between immune cells, keratinocytes and environmental triggers. We hypothesize that skin microbiome composit...

FO - Dermatovenerologie

  • 2015 - 2018
    • •
  • 6 426 tis. Kč
    • •
  • 6 426 tis. Kč
    • •
  • MZ
Project

The role of microbiome in the development of atopic dermatitis and food allergy in infants and toddlers (NU20-05-00038)

Atopic dermatitis (AD) is the most common chronic inflammatory skin disorder affecting up to 20% of children in industrialized countries during their first year dysbiosis not only on the skin but also in the gut of AD patients with ...

Immunology

  • 2020 - 2024
    • •
  • 12 364 tis. Kč
    • •
  • 12 364 tis. Kč
    • •
  • MZ
Project

Dynamics and possibilities of microbiome shaping in aquaculture (QL24010346)

The project studies and modulates the microbiome of fish and intensive aquaculture systems. Damage to natural microbiome causes stress, reduces welfare, slows spectrum, climatic conditions), microbiome has not been yet stud...

Fishery

  • 2024 - 2028
    • •
  • 16 967 tis. Kč
    • •
  • 14 401 tis. Kč
    • •
  • MZe
Project

Mapping interactions between essential metabolic pathways and intestinal microbiota (GJ17-24592Y)

at the level of key intermediates with respect to reduced or altered intestinal microbiome diversity. Biological materials (meconium, neonatal heel pricks and skin swabs and microbiome produced) will be profiled and quanti...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2017 - 2021
    • •
  • 4 514 tis. Kč
    • •
  • 4 514 tis. Kč
    • •
  • GA ČR
Project

Personalized medicine approach based on analysis of immunity and microbiota interactions as a tool to predict therapeutic response in patients with psoriasis (NW24-06-00509)

interactions. We hypothesise that skin and gut microbiome signatures can identify subtypes. Especially, the gut-skin axis, the interconnection between the two largest human organs......

Dermatology and venereal diseases

  • 2024 - 2027
    • •
  • 11 273 tis. Kč
    • •
  • 11 273 tis. Kč
    • •
  • MZ
Project

Microbiota as a biomarker for prediction of mucocutaneous adverse effects of biologics used in inflammatory bowel disease (NV18-09-00493)

paired with broad array of immunological methods to analyze gut and skin microbiota...

Microbiology

  • 2018 - 2022
    • •
  • 10 316 tis. Kč
    • •
  • 10 262 tis. Kč
    • •
  • MZ
Project

A new center for comprehensive determination of the microbiome in clinical practice (FX05030113_7888)

In recent years, the microbiome has become a focus of interest for a number of experts, as changes in the microbiome have already been identified in connection for microbiome analysis with consistent results and to establis...

Other clinical medicine subjects

  • 2024 - 2025
    • •
  • 23 664 tis. Kč
    • •
  • 11 812 tis. Kč
    • •
  • MPO
Project

Functional interaction between host gene regulation and the microbiome in the primate gut (LH15175)

The gut microbiome plays a vital role in the host physiological landscape (e.g. diet) are important drivers of gut microbiome composition in humans functional interactions between host gene regulation and the microbiome in ...

EE - Mikrobiologie, virologie

  • 2015 - 2017
    • •
  • 1 997 tis. Kč
    • •
  • 1 997 tis. Kč
    • •
  • MŠMT
Project

Vectors, symbionts and pathogens a complex story of Triatominae microbiomes (GM21-10185M)

on structure and development of their microbiomes, including interactions with transmitted into the principles of insect-bacteria symbiosis. We have proved that i) the microbiomes undergo ontogenetic diversity shift, ii) the domina...

Ecology

  • 2021 - 2025
    • •
  • 21 464 tis. Kč
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  • 21 464 tis. Kč
    • •
  • GA ČR
Project

Development of personalized microbiome nutrition (FW06010640)

The aim and scope of the submitted project is to develop a range of dietary supplements based on targeted microbiome nutrition for humans. The new products will allow for an effective impact on the gut microbiome together with tailo...

Nutrition, Dietetics

  • 2023 - 2026
    • •
  • 20 959 tis. Kč
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  • 13 226 tis. Kč
    • •
  • TA ČR
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