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3 750 (0,101s) •

Project

Molecular mechanism of spliceosomal snRNP formation (GA21-04132S)

Small nuclear ribonucleoprotein (snRNP) particles are key components to test the hypothesis that Gemin3 is necessary to open a compact snRNA structure to allow loading of Sm proteins onto snRNA. This is the first s...

Biochemistry and molecular biology

  • 2021 - 2023
    • •
  • 9 023 tis. Kč
    • •
  • 9 023 tis. Kč
    • •
  • GA ČR
Project

Quality control of spliceosomal snRNP assembly (GA15-00790S)

Biogenesis of small nuclear ribonucleoprotein particles (snRNPs) is a complex process that involves several sequential steps occurring both in the cytoplasm and the nucleus. In this project we propose to study cellular mechanisms th...

EA - Morfologické obory a cytologie

  • 2015 - 2017
    • •
  • 5 230 tis. Kč
    • •
  • 5 230 tis. Kč
    • •
  • GA ČR
Project

Topography of nuclear architecture associated with the RNA synthesis,processing and transport. (GV304/96/K002)

with the spatial distribution of RNAs. The explicite aim of this project is to show with the concomitant antibody mapping ofvarious factors directly involved in various steps of RNA metabolism, with ISH probes to snRNAs an...

EB - Genetika a molekulární biologie

  • 1996 - 1998
    • •
  • 4 209 tis. Kč
    • •
  • 4 209 tis. Kč
    • •
  • GA ČR
Project

Structural basis for transcription termination of nonpolyadenylated transcripts (IAA401630903)

RNA transcript. RNA Polymerase II transcribes not only mRNA but also a subset of small nuclear and small nucleoar RNAs, and a class of intergenic and anti-sense RNAsRNA polymera...

CE - Biochemie

  • 2009 - 2011
    • •
  • 4 875 tis. Kč
    • •
  • 4 875 tis. Kč
    • •
  • AV ČR
Project

Biogenesis of small nucleolar RNAs in the frame of nuclear architecture (GA304/00/P025)

Cell nucleus contains many small nucleolar RNAs (snoRNA) which are necessary-ribosomal RNA and in modification of ribosomal RNA (rRNA). All snorRNA are present. In this project we will focus on mapping of snoRNA bi...

EA - Morfologické obory a cytologie

  • 2000 - 2002
    • •
  • 201 tis. Kč
    • •
  • 201 tis. Kč
    • •
  • GA ČR
Project

Principles of snRNP sequestration into cellular structures (GA18-10035S)

Small nuclear ribonucleoprotein particles (snRNPs) are the key components of the spliceosome that catalyze pre-mRNA splicing. Assembly of snRNPs is a multistep process and mistakes in snRNP formation cause several hereditary disease...

Cell biology

  • 2018 - 2020
    • •
  • 7 865 tis. Kč
    • •
  • 7 376 tis. Kč
    • •
  • GA ČR
Project

Fertility limiting diseases of pelvic organs and their influence on receptivity of endometrial cavity prospective clinical trial (REAdME) (NU23-06-00327)

sequencing (HTS) of endometrial RNA at the tissue level as well as at the cell level. We...

Obstetrics and gynaecology

  • 2023 - 2026
    • •
  • 11 351 tis. Kč
    • •
  • 11 351 tis. Kč
    • •
  • MZ
Project

Metabolism of RNA and the nuclear architecture (IAA539401)

9F - 9

  • 1994 - 1996
    • •
  • 335 tis. Kč
    • •
  • 512 tis. Kč
    • •
  • AV ČR
Project

RNA Silencing and Transposable Elements in a Slug Laboratory Model (LL2411)

RNA silencing is a group of important evolutionarily related mechanisms that employ small-RNA guides for sequence-specific gene control, genome protection against transposable elements (TEs), and double-stranded RNA

Biochemistry and molecular biology

  • 2024 - 2026
    • •
  • 23 886 tis. Kč
    • •
  • 23 886 tis. Kč
    • •
  • MŠMT
Project

Topography of nuclear architecture associated with the RNA synthesis, processing and transport (GA304/96/0879)

9H - 9

  • 1996 - 1996
    • •
  • 0 tis. Kč
    • •
  • 4 962 tis. Kč
    • •
  • GA ČR
  • 1 - 10 out of 3 750