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6 571 (0,151s) •

Project

Preparation of immunoglobulins with defined specificities from milk, colostrum or eggs of immunized donors (EP0960006625)

Antibodies reacting specifically with the respective antigens are of essential importance in the development of biologicals intended for the diagnosis, passive therapy on the development and testing of methods of careful separation of im...

GJ - Choroby a škůdci zvířat, veterinární medicina

  • 1996 - 2000
    • •
  • 5 546 tis. Kč
    • •
  • 4 946 tis. Kč
    • •
  • MZe
Project

Investigation of regulatory components of the immunoglobulin translation machinery in multiple myeloma as novel therapeutic targets (GA22-26981S)

myeloma. The tremendous production of immunoglobulin is a typical myeloma hallmark of the ubiquitin system, particularly deubiquitinase OTUD1, in the immunoglobulin translation promotes immunoglobulin synthesis, 2) ubiquit...

Cell biology

  • 2022 - 2024
    • •
  • 9 065 tis. Kč
    • •
  • 9 065 tis. Kč
    • •
  • GA ČR
Project

Clonal analysis of antigen specific B lymphocytes from patients with rheumatoid arthritis using single-cell RT-PCR (NK7273)

Analysis of immunoglobulin genes on the mRNA level in individual citrulline specific B lymphocytes. Investigation of clonality of B cells and possible restricted usage and pairing of expressed VH and VL Ig genes. Conlusions deduced ...

FP - Ostatní lékařské obory

  • 2002 - 2004
    • •
  • 6 205 tis. Kč
    • •
  • 5 828 tis. Kč
    • •
  • MZ
Project

Innovative method of immunoglobulins administration (TJ04000443)

immunoglobulins. We assume w/o/w double emulsion enables the protection of immunogobulins gastrointestinal tract simulation. Furthermore, the release of immunoglobulins from the w/o/w immunoglobulins are required. Immu...

Chemical process engineering

  • 2020 - 2022
    • •
  • 3 799 tis. Kč
    • •
  • 3 209 tis. Kč
    • •
  • TA ČR
Project

Detection of carp immunoglobulins and their use in diagnosis of spring viraemia of carp (1B44022)

immunoglobulin which will be used as basic components for diagnosis of specific antibodies. Detection of specific antibodies seems to be perspective for analysis of the spring......

GJ - Choroby a škůdci zvířat, veterinární medicina

  • 2004 - 2007
    • •
  • 5 193 tis. Kč
    • •
  • 5 193 tis. Kč
    • •
  • MZe
Project

Identification of immunoglobulin and T-cell receptor genes rearrangements for detection of clonality and residual disease in lymphoid malignancies. (IZ3425)

The analysis of clonospecific rearrangements of T-cell receptor and immunoglobulin genes will improve the diagnosis of non Hodkin s lymphomas and monitoring of minimal residual disease in acute lymphoblastic leukemias in children.......

FG - Pediatrie

  • 1996 - 1999
    • •
  • 3 745 tis. Kč
    • •
  • 3 745 tis. Kč
    • •
  • MZ
Project

The study of the relation between Epstein-Barr virus infection and development of IgA nephropathy (NV15-33686A)

Immunoglobulin A nephropathy (IgAN) is autoimmune disease without known triggers contributing to clinical manifestation. In this application we propose antibodies specific galactose-deficient molecule. To examine this we propose for...

EC - Imunologie

  • 2015 - 2018
    • •
  • 6 427 tis. Kč
    • •
  • 6 427 tis. Kč
    • •
  • MZ
Project

Cytokines in relationship to immunoglobulin production in multiple sclerosis. (IZ2777)

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 1995 - 1997
    • •
  • 1 155 tis. Kč
    • •
  • 1 155 tis. Kč
    • •
  • MZ
Project

Mechanism of tissue inflammation in patients with polymyositis and dermatomyositis (NI5369)

lymphocyte subpopulations. Deposited immunoglobulins and their specificity with respect...

FE - Ostatní obory vnitřního lékařství

  • 1999 - 2001
    • •
  • 2 624 tis. Kč
    • •
  • 2 624 tis. Kč
    • •
  • MZ
Project

Antibodies to HLA antigens and their relevance for the develpoment of chronic rejection after kidney transplantation (NR7859)

to their HLA (or non-HLA) specificity, immunoglobulin class and dynamics of development....

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2004 - 2006
    • •
  • 2 869 tis. Kč
    • •
  • 2 709 tis. Kč
    • •
  • MZ
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