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1 719 (0,085s) •

Project

Startle reaction and prepulse inhibition in human with latent toxoplasmosis (GAP303/11/1398)

and schizophrenia using commonly utilized method of prepulse inhibition of the startle reaction...

FH - Neurologie, neurochirurgie, neurovědy

  • 2011 - 2015
    • •
  • 6 718 tis. Kč
    • •
  • 6 718 tis. Kč
    • •
  • GA ČR
Project

The role of retroviral proteins in brain dysfunction animal model of the schizophrenia (NR8797)

Effect of main HIV-1 proteins (glycoprotein 120-Gp120, Capsid protein-CA, Gag protein and nucleocapsid protein-NC) on brain development and possible interaction with neonatal brain will be studied. Prepulse inhibition of the acoustic startle...

FH - Neurologie, neurochirurgie, neurovědy

  • 2006 - 2009
    • •
  • 11 258 tis. Kč
    • •
  • 11 121 tis. Kč
    • •
  • MZ
Project

Levels of brain glutamate and subunit composition of glutamate receptor of NMDA type in schiziphrenia experimantal and clinical study. (NF7626)

with a defined dysfunction of glutamatergic. prepulse inhibition of the acoustic startle reaction will be evaluated in relation to the composition of NMDA receptor......

FH - Neurologie, neurochirurgie, neurovědy

  • 2003 - 2005
    • •
  • 11 456 tis. Kč
    • •
  • 11 252 tis. Kč
    • •
  • MZ
Project

Animal study based on studying mechanism of action of new synthetic drug 2C-B and comparaison with common psychotropic substances (LSD, MDMA, psilocin and mescaline) potential risks, implications for prevention and treatment of intoxications (NR8785)

Examination of behavioral changes and changes in prepulse inhibition of acoustic startle reaction induced by new synthetic drug 2C-B. Identification of serotonin and dopamine receptor subtypes involved in mechanism of drug´s action....

FP - Ostatní lékařské obory

  • 2006 - 2008
    • •
  • 8 780 tis. Kč
    • •
  • 7 507 tis. Kč
    • •
  • MZ
Project

Pathophysiological mechanisms of neuromodulation therapy in dystonia (NT12282)

The project is aimed at the study of the pathophysiological mechanisms of deep brain stimulation of the globus pallidus interna (GPi DBS) in dystonic patients. Using functional imaging (resting-state fMRI) and electrophysiological testing (single-pul...

FH - Neurologie, neurochirurgie, neurovědy

  • 2011 - 2015
    • •
  • 6 385 tis. Kč
    • •
  • 6 385 tis. Kč
    • •
  • MZ
Project

Acute behavioral changes and acute and chronic toxicity of synthetic psychedelic drugs and their combinations in rats (NJ7636)

Examination of the effect of co-administration of MDMA with LSD or psilocin to rats on behaviour (open field, elevated plus maze, startle test) and concurent measuring the neurotransmitter levels in the brain of freely moving rats using micr...

FL - Psychiatrie, sexuologie

  • 2003 - 2005
    • •
  • 6 510 tis. Kč
    • •
  • 5 996 tis. Kč
    • •
  • MZ
Project

Study of infectious diseases and their causative agents (GD310/05/H533)

In the last decade there has been a startling growth of the occurrence of infectious diseases (ID's) in developed countries. The risk of spread of pathogenic organisms to a new territory and the risk of onset and spread of a new infectious d...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2005 - 2008
    • •
  • 12 347 tis. Kč
    • •
  • 12 347 tis. Kč
    • •
  • GA ČR
Project

Glutamatergic theory of schizophrenia in animal and human models of disconnection tested by comparison with a population of schizophrenic patients (NR8792)

and sensomotor gating by prepulse inhibition of startle reflex (PPI), and on the expression...

FL - Psychiatrie, sexuologie

  • 2006 - 2008
    • •
  • 5 112 tis. Kč
    • •
  • 4 734 tis. Kč
    • •
  • MZ
Project

The role of serotonin and noradrenaline reuptake inhibitors as potential antidotes for intoxications with dangerous synthetic drugs 2C-B and DOB ? pharmacokinetics, behavioral and QEEG effects (NS10374)

behavioral changes (locomotion and prepulse inhibition of acoustic startle). Ad 4...

FP - Ostatní lékařské obory

  • 2009 - 2011
    • •
  • 5 344 tis. Kč
    • •
  • 5 344 tis. Kč
    • •
  • MZ
Project

Functional changes of the auditory system associated with auditory experience and aging (GA18-09692S)

The auditory system is undergoing significant changes during the life of an individual. These changes are particularly associated with the development, auditory experience and aging. The proposed project aims on three specific scenarios: (i) affectin...

Neurosciences (including psychophysiology)

  • 2018 - 2021
    • •
  • 6 539 tis. Kč
    • •
  • 6 506 tis. Kč
    • •
  • GA ČR
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