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12 (0,123s)

Project

NMR study of structure and stereochemistry of pentacyclic triterpenoids (GP203/05/P025)

This project is focused on structure and stereochemistry elucidation of pentacyclic triterpenoids using NMR spectroscopy. It is mainly concerns on artificially modified lupane or oleanane triterpenoids with interesting biological activity (e...

CC - Organická chemie

  • 2005 - 2007
  • 654 tis. Kč
  • 654 tis. Kč
  • GA ČR
Project

Exopolyhedral substitutions at metallacarborane cages and their stereochemistry (GA21-14409S)

is new knowledge about substitution and its stereochemistry with deeper focus...

Inorganic and nuclear chemistry

  • 2021 - 2023
  • 5 833 tis. Kč
  • 5 833 tis. Kč
  • GA ČR
Project

Microwave initiated syntheses (OC08052)

In the continuation of the already obtained results on intramolecular 1,3-dipolar cycloadditions, the aim of the project is to conclude explanation of the observed stereoselectivity. New structural models in the reaction will be examined.......

CC - Organická chemie

  • 2008 - 2008
  • 500 tis. Kč
  • 500 tis. Kč
  • MŠMT
Project

Reactivity of asymmetrically substituted epimino pyranoses (IAA400720703)

The aim of this project is to explore nucleophilic aziridine ring cleavage of 4-deoxy- and 4-fluoro-2,3-epimino derivatives of 1,6-anhydro-beta-D-hexopyranoses. A ionic SN1-like mechanism in competition with SN2 mechanism is expected to control the <...

CC - Organická chemie

  • 2007 - 2009
  • 603 tis. Kč
  • 603 tis. Kč
  • AV ČR
Project

NMR Toolbox for Probing Stereochemistry in Phosphorus-Containing Bioactive Molecules (GA21-23014S)

We aim to develop a new robust NMR methodology for stereochemical studies of phosphorus-containing molecules, which is still considered to be challenging. The core idea of the project lies in using 31P as a magnetically active isotope providing the k...

Analytical chemistry

  • 2021 - 2023
  • 5 851 tis. Kč
  • 5 688 tis. Kč
  • GA ČR
Project

Chirality-selective electron transport in single molecular devices (GA24-11064S)

The chirality-induced spin selectivity (CISS) effect describes the interaction between electron spin and the handedness of chiral molecules. Despite the significant attention CISS received recently there is still a lack of a comprehensive understandi...

Physical chemistry

  • 2024 - 2026
  • 8 489 tis. Kč
  • 8 485 tis. Kč
  • GA ČR
Project

From Amino Acids to Nature-Inspired Molecular Scaffolds (GA16-06446S)

compounds with 3D architecture and full control of stereochemistry that structurally...

CC - Organická chemie

  • 2016 - 2018
  • 5 922 tis. Kč
  • 5 922 tis. Kč
  • GA ČR
Project

Chemical synthesis of human pathogens proteases inhibitors (GP203/02/P095)

in the terms of synthesis of hydroxyethylamine group in dependence on stereochemistry...

CC - Organická chemie

  • 2002 - 2004
  • 750 tis. Kč
  • 625 tis. Kč
  • GA ČR
Project

Solid-phase synthesis of diversely constrained peptidomimetics. (GAP207/12/0473)

The aim of this proposal is to develop a general methodology for efficient and expeditious solid-phase synthesis of diversely constrained peptidomimetics with complete control of their stereochemistry. The proposed approach encompasses the f...

CC - Organická chemie

  • 2012 - 2014
  • 9 375 tis. Kč
  • 9 175 tis. Kč
  • GA ČR
Project

Overlooked phenomenon with significant impact - the chirality in cluster (metalla)carboranes. (GA25-16216S)

This project present a systematic focus on planar and axial chirality in inorganic boron cluster compounds, which surprisingly remains largely neglected. Representative series of selected new types of asymmetrically substituted neutral and ionic icos...

Inorganic and nuclear chemistry

  • 2025 - 2027
  • 9 966 tis. Kč
  • 9 966 tis. Kč
  • GA ČR
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