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99 (0,083s) •

Project

Study of structure-activity relationship of novel taxane derivatives for combating acquired resistance of cancer cells (LTAUSA19032)

The aim of proposed research is to elucidate modulatory effect of substituents to substituents at the C3´ and C3´N positions have capability to overcome acquired resistance modulatory effect of substituents at the C10 posit...

Oncology

  • 2019 - 2023
    • •
  • 5 710 tis. Kč
    • •
  • 5 710 tis. Kč
    • •
  • MŠMT
Project

New ligands for recognition of chiral anions (GP203/03/D134)

with the anions. The influence of substituents on the ability to interact with anions substituents and on the contrary electronically rich substituents. Substituents have......

CC - Organická chemie

  • 2003 - 2006
    • •
  • 1 086 tis. Kč
    • •
  • 750 tis. Kč
    • •
  • GA ČR
Project

Study of Substituent and Solvent Effects of Organic Compounds. (GA203/94/0122)

9J - 9

  • 1994 - 1996
    • •
  • 410 tis. Kč
    • •
  • 545 tis. Kč
    • •
  • GA ČR
Project

Transition metal complexes with cyclopentadienyl ligands for catalysis in fluorous biphase systems (GA203/99/0135)

The project concerns the synthesis and use in homogeneous catalysis of a novel type of ligands, cyclopentadienes substituted by polyfluorinated substituents effective ways of attachment of polyfluorinated substituents to cyclopentad...

CC - Organická chemie

  • 1999 - 2001
    • •
  • 1 799 tis. Kč
    • •
  • 1 318 tis. Kč
    • •
  • GA ČR
Project

Silicon-29 chemical shifts (GA203/99/0132)

documented (though not well understood) are the gross effects of substituents directly attached to the silicon atom in question. Effects of remote substituents, which of the silyl-substituent on the extent to which steric ...

CA - Anorganická chemie

  • 1999 - 2001
    • •
  • 1 404 tis. Kč
    • •
  • 1 112 tis. Kč
    • •
  • GA ČR
Project

Metallocene catalysts anchored on mesoporous support of the MCM-41 type (IBS4040017)

Titanocene and zirconocene complexes containig very bulky unsaturated substituents on cyclopentadienyl ligands and sereis of the metallocene complexes with pendat -alkenyl substituents of different lengths on cyclopentadienyl su...

CF - Fyzikální chemie a teoretická chemie

  • 2000 - 2002
    • •
  • 2 865 tis. Kč
    • •
  • 1 160 tis. Kč
    • •
  • AV ČR
Project

Chemical structure and biodegradability of complex - forming substances (GA203/97/0701)

probably depend on the number of ethylenediamine units and their substituents by different substituents (CH3, C2H5, CH2CH2OH, CH2COOH in various combination).......

DJ - Znečištění a kontrola vody

  • 1997 - 1999
    • •
  • 1 051 tis. Kč
    • •
  • 680 tis. Kč
    • •
  • GA ČR
Project

Synthesis and cytostatic activity studies of novel 2,6- and 6,8-disubstituted purine bases and nucleosides (IAB4055201)

introduce C-substituents into these position. Depending on the nature of dihalopurine. By this approach, a large series of title purine bases and nucleosides bearing C-substituent in position 2,6 or 8 in combination with another

CC - Organická chemie

  • 2002 - 2004
    • •
  • 1 333 tis. Kč
    • •
  • 665 tis. Kč
    • •
  • AV ČR
Project

Syntheses of the 4 - substituted nucleoside carba analogs with potentional antiviral effects (GA203/97/0375)

to preparederivatives with azido, carboxyl, cyano, hydroxymethyl and other substituents substituent. The prepared compounds will be screened against selected RNA and DNA viruses......

CC - Organická chemie

  • 1997 - 1999
    • •
  • 920 tis. Kč
    • •
  • 322 tis. Kč
    • •
  • GA ČR
Project

Evaluation of substituent effects in isolated molecules (GA203/96/1658)

Classical textbook terms of substituent effects, supported mainly by the reactivity in solution, will be systematically reinvestigated on the basis of the properties of isolated molecules, i.e. on the acid-base equilibrium constants in the g...

CC - Organická chemie

  • 1996 - 1998
    • •
  • 516 tis. Kč
    • •
  • 350 tis. Kč
    • •
  • GA ČR
  • 1 - 10 out of 99