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543 (0,109s) •

Project

Buprenorphine substitution on substance-using pregnant women, its influence on pregnancy, postpartum adaptation of neonate and social adapation. (NR8450)

Evaluation of neonatal abstinence syndrome degree during methadone or buprehorphine substitution during pregnancy. Evaluation of neonatal abstinence syndrome degree commensurate with dosage of substitution treatment. Evaluation of i...

FK - Gynekologie a porodnictví

  • 2005 - 2007
    • •
  • 2 190 tis. Kč
    • •
  • 2 108 tis. Kč
    • •
  • MZ
Project

Nucleoside carba analogues containing substituted cyclohexanes compounds with potential biological effects (GA203/02/0035)

In continuation of our previous studies aimed at the syntheses of the 4''-substituted deoxynucleosides with potential antiviral activity, this research project concerns syntheses of the novel 4'' substituted carbocyclic nucleoside a...

CC - Organická chemie

  • 2002 - 2003
    • •
  • 702 tis. Kč
    • •
  • 244 tis. Kč
    • •
  • GA ČR
Project

Development of new methodologies towards (pentafluorosulfanyl)benzenes. (GAP207/12/0072)

We propose to investigate the following reactions of nitro-(pentafluorosulfanyl)benzenes: (a) nucleophilic aromatic substitution for the nitro group, (b) oxidative nucleophilic aromatic substitution for the hydrogen and (c) vicariou...

CC - Organická chemie

  • 2012 - 2014
    • •
  • 1 958 tis. Kč
    • •
  • 1 958 tis. Kč
    • •
  • GA ČR
Project

Optimization of nanostructured dermal substitutes in animal model (NV17-29874A)

The artificial skin substitutes are applied in the treatment of chronic skin nanostructured bio-substitute is consisted of antibacterial collagen/chitosan porous sponge (dermal substitute) doped with hyperstable fibroblast ...

FJ - Chirurgie včetně transplantologie

  • 2017 - 2020
    • •
  • 11 634 tis. Kč
    • •
  • 11 634 tis. Kč
    • •
  • MZ
Project

Syntheses of the 4 - substituted nucleoside carba analogs with potentional antiviral effects (GA203/97/0375)

In continuation of the previous studies aimed at the syntheses of 4'-C-substituted deoxynucleosides with a potential antiviral activity, this research project concerns syntheses of novel 4'-substituted 2'-deoxynucleoside carba analo...

CC - Organická chemie

  • 1997 - 1999
    • •
  • 920 tis. Kč
    • •
  • 322 tis. Kč
    • •
  • GA ČR
Project

Molecular biology and structure funcition studies of multiple substitution mutants of mitochondrial uncoupling protein (GA301/98/0568)

studies of the reconstituted multi-substituted UcP mutants expressed in yeast, since the single substitutions (e. g. Cys) did not bring a unifying view. On the contraryexchange up to four Cys did not alter UcP function, but the

EB - Genetika a molekulární biologie

  • 1998 - 2000
    • •
  • 3 255 tis. Kč
    • •
  • 2 042 tis. Kč
    • •
  • GA ČR
Project

Exopolyhedral substitutions at metallacarborane cages and their stereochemistry (GA21-14409S)

Proposal covers new types of substitution reactions at isomeric cobalt bis of direct substitution at carbon and boron atoms with the aim to synthesize derivatives on substitution with two different substituents and/or bridg...

Inorganic and nuclear chemistry

  • 2021 - 2023
    • •
  • 5 833 tis. Kč
    • •
  • 5 833 tis. Kč
    • •
  • GA ČR
Project

Modified oligonucleotides derived from 5´-substituted nucleoside 5´-C-phosphonates synthesis and hybridization properties (GP203/04/P273)

linkages derived from 5´-substituted nucleoside 5´-C-phosphonates in the project, and their physico-chemical properties will be studied and the influence of 5´-substitution´- and 5´-substituted 5´-C-phosphonate analogues w...

CC - Organická chemie

  • 2004 - 2006
    • •
  • 806 tis. Kč
    • •
  • 806 tis. Kč
    • •
  • GA ČR
Project

Enzymatic hydrolysis of acrylonitriles substituted on the alpha-carbon by a (poly)hydroxylated side chain (ME 579)

Microbial cells and enzymes catalyzing the hydration and/or hydrolysis of nitriles are applied in the biotransformations of acrylonitriles substituted on the alpha-carbon with a side chain bearing hydroxyl(s). These compounds are important s...

CC - Organická chemie

  • 2002 - 2002
    • •
  • 233 tis. Kč
    • •
  • 105 tis. Kč
    • •
  • MŠMT
Project

Urological and endocrinological factors of hormonal substitution therapy in patients with Kallmann syndrome (NS9983)

The project is focused on the determination of the relationship of the urological and endocrinological factors of hormonal substitution therapy in patients approach and specification of risk hormonal substitution therapy in patients...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2008 - 2011
    • •
  • 1 649 tis. Kč
    • •
  • 1 649 tis. Kč
    • •
  • MZ
  • 1 - 10 out of 543