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MIcro and MAcro Connectomics of the Subthalamic nucleus in humans impact of neuromodulation and dopamine depletion (GA16-13323S)
The subthalamic nucleus (STN) is an important subcortical structure of the brain and a common target for deep brain stimulation (DBS) in the treatment of Parkinson’s disease. Despite its excellent effects on movement, STN DBS is accompanied ...
FH - Neurologie, neurochirurgie, neurovědy
- 2016 - 2020 •
- 9 921 tis. Kč •
- 9 612 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2016 - 22. 7. 2020
Uznané náklady
Podpora ze státního rozpočtu (97%)
Poskytovatel: Grantová agentura České republiky
Mechanisms of deep brain stimulation Role of the subthalamus in motor, visual and affective processing (GA309/09/1145)
Deep Brain Stimulation (DBS) of the subthalamic nucleus (STN) is an important method of treatment for Parkinson?s disease. Though there is little doubt about the beneficial effects of STN DBS on motor functions, our knowledge of the neurosti...
FH - Neurologie, neurochirurgie, neurovědy
- 2009 - 2012 •
- 5 242 tis. Kč •
- 5 224 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2009 - 31. 12. 2012
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Modulation of functional connectivity of the large scale cortical networks by STN DBS (NV16-33798A)
Deep brain stimulation (DBS) is an effective long-term treatment for motor symptoms in advanced Parkinson's disease (PD). The most frequently used target is the subthalamic nucleus (STN). For some patients, the beneficial motor effects may b...
FH - Neurologie, neurochirurgie, neurovědy
- 2016 - 2019 •
- 8 881 tis. Kč •
- 8 881 tis. Kč •
- MZ
Řešení projektu: 1. 4. 2016 - 31. 12. 2019
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Reducing speech-related side-effects of deep brain stimulation in Parkinson's Disease via automated speech analysis (GF21-14216L)
Deep brain stimulation of the subthalamic nucleus (STN-DBS) is an effective treatment of motor symptoms of Parkinson’s disease (PD), but its effects on speech are equivocal. Although some aspects of speech might improve with STN-DBS, stimula...
Medical engineering
- 2021 - 2023 •
- 7 182 tis. Kč •
- 7 182 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2021 - 31. 12. 2023
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Clinical, Imaging and Biological predictors of effects associated with deep brain stimulation in Parkinson’s disease (NV19-04-00233)
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is a common treatment for intermediate and late stages of Parkinson’s disease (PD). The development of PD is associated with the progression of several non-motor symptoms that may...
Clinical neurology
- 2019 - 2023 •
- 14 978 tis. Kč •
- 14 894 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2019 - 31. 12. 2023
Uznané náklady
Podpora ze státního rozpočtu (99%)
Poskytovatel: Ministerstvo zdravotnictví
Subcortical nuclei and cortical functions – insight from the deep brain stimulation perspective (GA21-25953S)
Exact knowledge of the role of the subcortical nuclei and their cortical relations in physiological and pathophysiological conditions still remains insufficiently explained. Deep brain stimulation (DBS) is an established treatment for late motor symp...
Clinical neurology
- 2021 - 2023 •
- 8 656 tis. Kč •
- 8 381 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2021 - 31. 12. 2023
Uznané náklady
Podpora ze státního rozpočtu (97%)
Poskytovatel: Grantová agentura České republiky
STN-DBS outcomes in Parkinson´s disease the influence of vascular, cardiovascular, metabolic, and inflammatory co-morbidities (NU21-04-00445)
Deep brain stimulation (DBS) is an established treatment for late motor symptoms in Parkinson’s disease (PD). Although DBS is generally a successful therapy, it has limitations including insufficient clinical effects and adverse side effects. The eff...
Clinical neurology
- 2021 - 2024 •
- 11 803 tis. Kč •
- 11 803 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2021 - 31. 12. 2024
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
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