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920 (0,09s) •

Project

Study of Calcium-Mediated Modulation of Glutamate Receptors and Excitatory Synaptic Transmission (GA309/93/0587)

CE - Biochemie

  • 1993 - 1995
    • •
  • 259 tis. Kč
    • •
  • 518 tis. Kč
    • •
  • GA ČR
Project

Molecular, cellular, and behavioral effects of NMDA receptor-modulating steroids (GA17-02300S)

effect at NMDARs, how they affect synaptic transmission, and what effect they have of cholesterol on synaptic transmission. for the induction of various forms of synaptic plasticity. A combined biophysica...

FH - Neurologie, neurochirurgie, neurovědy

  • 2017 - 2021
    • •
  • 7 914 tis. Kč
    • •
  • 7 161 tis. Kč
    • •
  • GA ČR
Project

Properties of glutamate receptors involved in synaptic transmission in spinal cord motoneurones and interneurones. Lecture on the ENA Conference (PG98058)

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ED - Fyziologie

  • 1998 - 1998
    • •
  • 49 tis. Kč
    • •
  • 33 tis. Kč
    • •
  • MŠMT
Project

Synaptic transmission in suprachiasmatic nucleus (GA309/99/0215)

predominantly by glutamate but also by neuropeptide Y and GABA. Synaptic transmission within to record spontaneous synaptic currents from SCN neurones in culture or in different......

ED - Fyziologie

  • 1999 - 2001
    • •
  • 1 556 tis. Kč
    • •
  • 1 115 tis. Kč
    • •
  • GA ČR
Project

Role of proteins associated with Cannabinoid receptor CB1 in trafficking (IAA500390701)

The fine-tuning of synaptic transmission and synaptic plasticity is necessary for harmonious neuronal network activity. Our project is precisely aimed at understanding emerged as an important mechanism of synaptic ...

FH - Neurologie, neurochirurgie, neurovědy

  • 2007 - 2011
    • •
  • 7 899 tis. Kč
    • •
  • 7 899 tis. Kč
    • •
  • AV ČR
Project

Synaptic Effects and Neuroprotective Properties of NMDA Receptor-Modulating Neurosteroids (GJ16-03913Y)

, but glutamate excess leads to excitotoxic neurodegeneration. Synaptic activation of NMDA receptors plays a key role in synaptic plasticity and can be neuroprotective. These properties predict that PA-S may selectively inhibit to...

ED - Fyziologie

  • 2016 - 2020
    • •
  • 4 509 tis. Kč
    • •
  • 4 509 tis. Kč
    • •
  • GA ČR
Project

Role of membrane domains of NR1 and NR2 subunits in the assembly and trafficking of the NMDA receptor to the cell surface (GAP303/11/0075)

N-methyl-D-aspartate (NMDA) receptors mediate fast excitatory synaptic transmission in the mammalian central nervous system. Activation of NMDA receptors can trigger several forms of synaptic plasticity and their abnormal r...

FH - Neurologie, neurochirurgie, neurovědy

  • 2011 - 2013
    • •
  • 4 160 tis. Kč
    • •
  • 4 160 tis. Kč
    • •
  • GA ČR
Project

The role of GABA-B receptors in the mammalian MNTB (GA309/06/1304)

GABAB receptors (GABABRs) modulate synaptic transmission by controlling neurotransmitter release and by inducing postsynaptic hyperpolarization. At many central of pre- and postsynaptic GABABRs to modulation of synaptic

FH - Neurologie, neurochirurgie, neurovědy

  • 2006 - 2008
    • •
  • 2 610 tis. Kč
    • •
  • 2 610 tis. Kč
    • •
  • GA ČR
Project

The role of cytokines and chemokines in the nociceptive signaling (GPP303/12/P510)

regulate synaptic transmission, but the mechanisms are not understood. In this proposal to further identify the mechanisms of nociceptive synaptic modulation by cytokines......

ED - Fyziologie

  • 2012 - 2014
    • •
  • 2 619 tis. Kč
    • •
  • 2 619 tis. Kč
    • •
  • GA ČR
Project

Mechanisms of Neuropathic Pain States (LH12058)

The aim of this project proposal is to study the influence of synaptic transmission modulation of nociceptive signalling at the spinal cord level in neuropathic pain states. Neuropathic conditions will be studied using models of per...

FH - Neurologie, neurochirurgie, neurovědy

  • 2012 - 2015
    • •
  • 3 546 tis. Kč
    • •
  • 3 382 tis. Kč
    • •
  • MŠMT
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