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5 073 (0,081s) •

Project

Metrology for emerging targeted alpha therapies (9B23008)

The overall objective of the project is to address the unique and unmet metrological challenges of targeted alpha therapies....

Nuclear physics

  • 2023 - 2026
    • •
  • 11 873 tis. Kč
    • •
  • 5 937 tis. Kč
    • •
  • MŠMT
Project

Targeted experimental therapy of leukemia by the specific action of antireceptor monoclonal antibodies (NR8233)

Selection and development of new therapeutically useful antibodies for targeted therapy of acute and chronic myeloid leukemia....

FD - Onkologie a hematologie

  • 2004 - 2006
    • •
  • 6 514 tis. Kč
    • •
  • 5 948 tis. Kč
    • •
  • MZ
Project

*Targeted supercancerostatics of new generation for leucemia therapy. (FT-TA2/081)

*Technology of specific ligands production development targeted for complexation of radionuclides. Ligands will be content reactive functional groups for conjugation with monoclonal antibody antiCD66. The conjugate will be applied in leucemi...

CC - Organická chemie

  • 2005 - 2008
    • •
  • 70 398 tis. Kč
    • •
  • 48 451 tis. Kč
    • •
  • MPO
Project

Recognition and Validation of Druggable Targets from the Response to Cognitive Behaviour Therapy in Myotonic Dystrophy type 1 patients from Integrated -Omics Networks (8F19001)

IRDiRC targets. "1000 new therapies for rare diseases - molecular biomarkers for CBT, CBT life-style interventions"....

Health-related biotechnology

  • 2019 - 2021
    • •
  • 5 099 tis. Kč
    • •
  • 5 099 tis. Kč
    • •
  • MŠMT
Project

Labelling of monoclonal antibodies with At-211 for targeted cancer therapy (KJB4048302)

Radionuclide AT-211 is one of a few promising alpha emitters for targeted therapy of tumours, which cannot be treated by other methods. Cyclotron U-120M separation from a target and development of analytical methods for qua...

CH - Jaderná a kvantová chemie, fotochemie

  • 2003 - 2005
    • •
  • 1 656 tis. Kč
    • •
  • 1 336 tis. Kč
    • •
  • AV ČR
Project

Use of molecular predictors for optimum selection of targeted therapy of non-small cell lung cancer (NR9087)

of therapy schemes and relationships between genetic predictors and the overall response to therapy.150 patients with confirmed NSCLC stage III.A., III.B and IV. will be indicated to chemotherapy according to the status of genetic ...

FD - Onkologie a hematologie

  • 2006 - 2008
    • •
  • 4 158 tis. Kč
    • •
  • 4 158 tis. Kč
    • •
  • MZ
Project

Efficient Low-energy Electron Cancer Therapy with Terbium-161 (TO01000074)

The main aim of the project is the R&D of novel radiopharmaceuticals based on terbium-161 and novel vectors for targeted therapy of tumors. The advantage of Tb-161 tomographic imaging and therapy follow-up. This will allow ...

Inorganic and nuclear chemistry

  • 2021 - 2024
    • •
  • 40 548 tis. Kč
    • •
  • 29 418 tis. Kč
    • •
  • TA ČR
Project

Metabolic adaptations of cancer cells The role of amino acid metabolism in cancer resistance and treatment (GA25-18052S)

to mitochondrially targeted iron chelators, leading to new approaches to therapy and identification of unexpected synergies. Identification of new targets that might be employed for cancer therapy and patient stra...

Biochemistry and molecular biology

  • 2025 - 2027
    • •
  • 9 804 tis. Kč
    • •
  • 9 804 tis. Kč
    • •
  • GA ČR
Project

Smart Photosenzitizers Highly-Effective, Activatable and Aptamer-Targeted (LL2318)

for the therapy of cancer and viral diseases by targeted photodynamic therapy. The sub to study the interaction of conjugates with target proteins using QCM-D technology of anticancer and antiviral therapy

Organic chemistry

  • 2023 - 2025
    • •
  • 14 158 tis. Kč
    • •
  • 14 158 tis. Kč
    • •
  • MŠMT
Project

Anticancer Therapy by Antibody Targeted Cytostatics (GA307/93/0057)

9F - 9

  • 1993 - 1995
    • •
  • 541 tis. Kč
    • •
  • 1 082 tis. Kč
    • •
  • GA ČR
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