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Complex liposomal forms of photosentitizers for experimental photodynamic therapy of tumors (NR7778)
on quantifying mRNA for telomerase and MCM proteins - rich regions will be considered...
FD - Onkologie a hematologie
- 2004 - 2009 •
- 8 383 tis. Kč •
- 4 651 tis. Kč •
- MZ
Řešení projektu: 1. 1. 2004 - 31. 12. 2009
Uznané náklady
Podpora ze státního rozpočtu (55%)
Poskytovatel: Ministerstvo zdravotnictví
Involvement of telomerase in the cell interactome (GA18-07027S)
recently proteins that may function as interaction partners of plant telomerase in vivo. We aim to elucidate their functional relationship with Arabidopsis telomerase and its telomeric and/or non-telomeric functions. These...
Plant sciences, botany
- 2018 - 2021 •
- 12 531 tis. Kč •
- 11 628 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2018 - 31. 12. 2021
Uznané náklady
Podpora ze státního rozpočtu (93%)
Poskytovatel: Grantová agentura České republiky
Interaction partners of plant telomeres and telomerases (LH13052)
with plant telomerase protein subunit will be investigated in vitro and in vivo by telomerase. Creation of functional model of plant telomerase interactome is neccessary nontelomericfunctions of telomerase
EB - Genetika a molekulární biologie
- 2013 - 2015 •
- 1 751 tis. Kč •
- 1 751 tis. Kč •
- MŠMT
Řešení projektu: 1. 3. 2013 - 31. 12. 2015
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo školství, mládeže a tělovýchovy
Structural and functional components of plant telomeres (GA13-06943S)
maintained by telomerase activity. Proposed project involves comprehensive studies of (i) protein structure and interactions of plant telomeres; (ii) telomerase complex regulation; and (iii) evolution of the telomerase...
EB - Genetika a molekulární biologie
- 2013 - 2017 •
- 19 576 tis. Kč •
- 19 576 tis. Kč •
- GA ČR
Řešení projektu: 1. 2. 2013 - 31. 12. 2017
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
The molecular mechanism of telomerase inhibition targeted defeat of cancer cell proliferation (GA16-20255S)
the dynamics and kinetics of critical interactions of human telomerase and its protein proliferate. Telomeric DNA extension by telomerase thus contributes to the immortalization the mechanism of telomerase action ...
BO - Biofyzika
- 2016 - 2018 •
- 7 569 tis. Kč •
- 6 840 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2016 - 31. 12. 2018
Uznané náklady
Podpora ze státního rozpočtu (90%)
Poskytovatel: Grantová agentura České republiky
Roles of ARM proteins in signalling pathways and regulation of gene expression (GA21-28265S)
Biological roles of ARM proteins in plants and of ARMC proteins in animals were not fully investigated. We have identified recently Arabidopsis ARM protein as a part of telomerase interaction network but most likel...
GM technology (crops and livestock), livestock cloning, marker assisted selection, diagnostics (DNA chips and biosensing devices for the early/accurate detection of diseases) biomass feedstock production technologies, biopharming
- 2021 - 2024 •
- 5 512 tis. Kč •
- 5 512 tis. Kč •
- GA ČR
Řešení projektu: 1. 7. 2021 - 31. 12. 2024
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Biogenesis and evolution of telomerase in plants (GX20-01331X)
and other associated proteins – to address a problem of telomerase biogenesis in plants other things, with the observations of: i) reversible regulation of telomerase. The answer is presumably hidden in the most important ...
GM technology (crops and livestock), livestock cloning, marker assisted selection, diagnostics (DNA chips and biosensing devices for the early/accurate detection of diseases) biomass feedstock production technologies, biopharming
- 2020 - 2024 •
- 48 597 tis. Kč •
- 48 597 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2020 - 31. 12. 2024
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Understanding of HMGB1 protein involvement in maintaining genome stability (GA204/08/1530)
identified HMGB1 as a telomerase-associated protein in vitro. As most, if not all, tumor status of tumor suppressor protein p53 on: (i) the activity of telomerase; (ii) theHMGB1 is a relatively abundant chromatin-...
CE - Biochemie
- 2008 - 2010 •
- 4 887 tis. Kč •
- 4 887 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2008 - 31. 12. 2010
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Dynamics of shelterin complex assembly (GAP205/12/0550)
at each DNA replication if the telomerase enzyme is not activated. Telomerase, telomerase activation in stem cells and cancer cells contributes to their unlimited proliferation potential. The telomerase access to ...
BO - Biofyzika
- 2012 - 2015 •
- 8 688 tis. Kč •
- 8 688 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2012 - 31. 12. 2015
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Molecular evolution and functional analysis of components of plant telomeres and telomerases (GA521/05/0055)
degradation and fusions. Many organisms use telomerase, comprising telomere reverse transcriptase (TERT) and telomerase RNA (TR), to replenish ends of chromosomal DNA lost and telomerase evolution and function of component...
EB - Genetika a molekulární biologie
- 2005 - 2007 •
- 3 792 tis. Kč •
- 3 792 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2005 - 31. 12. 2007
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
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